To add to this conversation, with some more recent info, this is the list of companies who use the sabinsa curcumin c3 complex in their products. Keep in mind that AFI is the sister company for Sabinsa, and only they can say what is exactly in their product, as the other companies purchase their curcumin from Sabinsa, but according to what I was told by AFI they can cut this product with another type of curcumin and add other ingredients that could affect it.
The following companies use Sabinsa's Curcumin C3 Complex
® in their products:
- Ageless Cures LLC
- America’s Finest
- BlueBonnet Nutrition
- Designs For Health
- Doctor’s Best
- Futurebiotics
- Progressive Laboratories, Inc.
- Pure Prescriptions
As we identify more customers who are users of Curcumin C3 Complex
®, we will report that here.
Life Extension Foundation, Florida does not use Sabinsa’s Curcumin C3 Complex
® in their products.
I also wrote Dr. Aggarwal, asking about the bioperine because stomach irritation is a concern for me, and he too advised 8G a day beginning at 1000mg and building up, although my doctor advises his patients to limit it to 3G a day, as he has had patients turn yellow, etc...But at the same time, his nurse said you could do what you want and see as it's not a prescrip medication. It's a shame that oncologists don't have more useful info and certainly about supplements they are suggesting.
Dr. Aggarwal, informed me by email, that "bioperine makes no discernable difference", and he said to mix it in yogurt or milk. He said nothing about full fat yogurt, etc. It's not so easy to mix it either, as one has to kind of crush it with a spoon or you get a chunk in your mouth, not pleasant at all.
So, this being the case, I began with the AFI Curcuminoids which is the C3 curcumin without bioperine and I am opening the 500mg capsules and mixing it with stonyfield 2% yogurt which has some fat. He also advises to take it on empty stomach 1 hr before meals so I'm doing it in the morning.
BUT. what I would like to know is what are the definitive comparisons to the following, and according to Margaret, it is really best to stay away from the BCM95 because at least for my purposes, the myeloma numbers went up for her and another person who was doing the experiment with her, and I've read some other negative things about it--so, I would stay away from BCM95 preparations. Note also, that in the Sabinsa list of companies that use C3, they make a statement that Life extension does NOT USE their C3, they are doing that for a reason, because it is not the same at all.
http://www.consumerl...view/2_16_2011/this link was also on margaret's site, so keep in mind curcumin is all not equal.
CURRENT CONSIDERATIONS:
Longvida, this link answers lots of questions, however, I want to know which type of curcumin they are using, and I don't seem to see this or understand it,..I am writing them an email to get clarification:
http://www.longvida....t-Curcumin.htmlhttp://shop.nutrasal...tegory_s/47.htm Optima C-PC was mentioned to me on Margaret's blog with good results and it appears at this link it is out of stock and it says, new 2 piece veggie caps coming...looks very interesting...http://shop.nutrasal.com/v/vspfiles/manual_downloads/Optima%20CPC_Information_Brochure_Rev1_100212.pdf
when one reads through this link it appears that this product is the longvida..so what is the difference between these 2? I will email and ask.
And both the products above do not contain Bioperine, which certainly if one is taking 8 grams a day of curcumin with a bioper product like Doctor's best they are getting at least 40mg of bioperine a day and that is increasing everything else they are taking also. I think this could be problematic, although there are many like Margaret, who has been doing this for years with no ill effect...but, I've got a gastro sensitivity so, I think it's best for me to deal without it, especially when Dr. Aggarwal, clearly stated to me, "bioperine makes no discernable difference"..I think it's a simlar situation as the emodin that is in the reservatrol which I'm also trying to navigate. And as far as the green tea thing, just drink a cup or 2 and be done with it, but my doctor reccomended Theaflavin by Life exten to take--so, try that instead.
And, so, I think the current thinking is the jury is out on these above products (perhaps I will use myself as guinea pig)--and the BCM95 is an avoid, and the C3 companies listed above, tread carefully since all of them have bioperine, except for AFI which has the curcuminoids, at 500mg which is the one I'm taking that does not have the bioperine and opening the casules. Here it is:
http://www.afisupple...9Jq7s6yZXgqHcLgand there is the MERIVA CURCUMIN....so, I'm very confused as to the difference between the meriva and above stuff...but this article quoting the head of sabinsa does give a pretty accurate description, indicating it enhances something else, but not the curcumoids which is most effective--he also says that over 20mg of bioperine is not a good thing--so, am I right? The curcuminoids plain is the way to go, and supplement with green tea, and other stuff..maybe some quercetin pills????
http://www.nutraingr...lability-debateHope this clears up some confusions, and I would LOVE to hear from anyone who's been using these above products and can offer some clear on technical explanations for those of us that aren't so scientifically saavy!. Thanks!
One more thing, great post from kennedydisease forum where all types are listed:HERE IT IS BELOW___________________________________
":subject of today's post is the proliferation of new versions of curcumin. Plain ordinary curcumin is not well absorbed by the body, so about 80% to 90% of what you ingest passes through unchanged. Researchers are trying to solve that problem, and they have invented many different forms of curcumin. Following is a partial list:"
1. Turmeric (the spice, ground-up).
2. Curcumin (a powdered extract of turmeric).
3. Curcumol (an oil-based liquid extract of turmeric).
4. Curcumin with piperine, a black pepper extract that is believed to block intestinal enzymes that break down the curcumin.
5. Longvida, which was invented at the University of California. It is a form of curcumin that is coated with lipids, which are fatty-oily particles that are claimed to protect the curcumin and facilitate its transport across membranes.
6. Meriva, which was invented by the Italian pharma company Indena SpA. It consists of curcumin coated with phosphatidylcholine, claiming benefits similar to #4.
7. BCM-95 or Biocurcumax, which comes from the Indian pharma company Arjuna. It consists of curcumin coated with essential oil of turmeric, claiming benefits similar to #4 and #5.
8. Nanocurcumin, which was invented by a cooperative project between Johns Hopkins University and the University of Delhi. This one has curcumin encapsulated in nanoparticles that are claimed to protect it and increase solubility.
9. Dimethoxycurcumin or ASC-J9, which is being investigated by AndroScience Corp. It is a modified version of the curcumin molecule that is claimed to have better efficacy and better absorption into the body, but is not yet available to the public.
10. ASC-JM17, which is similar to ASC-J9 but designed to be taken by mouth rather than by injection.
Well, folks, I have read all the claims and I do not know which ones, if any, are true or false. The only thing certain is, taking #1 or #2 above (plain turmeric or curcumin) is not going to work, since very little is absorbed.
For my part, I am taking #5 (curcumin with phosphatidylcholine, 500 mg daily). I am not noticing any apparent negative effects, and I might be having a small improvement in certain symptoms such as fasciculations and cramps, but I am not sure.
LongeCity
