Posted 15 July 2010 - 06:12 AM
Right now, I'm thinking that there's definitely potential for a connection here.
I've mentioned that reducing (eliminating, really) excessive sugar intake about a year ago may have led to me require an acetylcholine booster, whereas before I'd taken piracetam for a long time without one. ALCAR worked immediately and completely, and remained effective for about 7 months by itself.
Pasta has been my staple food for most of my life. Even though my diet was fairly "balanced" in a traditional sense, I was pretty easily getting the majority of calories from carbohydrates. Over the past month or so, I've phased out pasta almost completely. I'm not low carb by any stretch, but probably have the macronutrients more or less balanced.
In the past two weeks, piracetam usage has become problematic for me. I don't get the irritability that you and others describe, but have other negative effects. In short: lack of desire to do anything (having trouble enjoying activities), mental fatigue but inability to sleep, verbal confusion, and general decrease in executive quality.
My first sad thought was that piracetam had stopped working for me, as a few others have reported in the non-responders thread. But at least partially-successful experiments with lecithin and Alpha GPC (along with my ever-present ALCAR) have convinced me that I've become suddenly burdened with the kind of cholinergic problem many beginning piracetam users have.
One of the implications of this experience is that ALCAR worked for me as a choline source by itself because I was on a relatively high-carb diet. It's still doing something, as 7 months ago I couldn't stand taking piracetam for more than 3-4 days before the effects described became almost mentally debilitating.
Anyway, just wanted to add that to this thread, for the sake of compiling data about dietary influence.