16 replies to this topic

[jans]

Just heard this on CNN, so searched and found this link below, what do you think iis G5?? -- a regenerative drug, since its principle function is to re-enable the body’s own regenerative functions. The drug that was discovered by the scientists almost by accident boosts the body’s production of stem cells, which enable the regeneration of the body’s organs and tissue.

http://indrus.in/eco...lves_23507.html

The people in the writing seem fake as does the writer, may be you people know more how to varify

[jans]

So it is on Euronews, http://www.euronews....out-youth-pill/ but what is it?
Why reproduce the fake news?? http://www.setyoufre...-on-themselves/
Lies are fastest to spread, specially when there is clout for that, in few days there is probably 10 x more bloger links then now: https://www.google.e...lient=firefox-a

Aquincidence or not? Secrecy and code names?
The Journalist is a Pussy Riots Janotor, at least there is noone in RIA novosty by this name Yelena Zhukova
the expert in the article is a Banker - Andrei Bekarev his address listed at http://eng.fipa.khab...debook/contact/ and the only person with this name in the World and in the siberian town http://investing.bus...nt Express Bank
Scientific Future Management - does not exist, http://www.russmed.ru/eng/ramn.htm at least on paper.

[renfr]

This is Scientific Future Management : http://translate.goo...w.scpb.ru/about

Company "SPS" operates on management of the holding.

In June 2008, between the Company "SPS" and the Mayor's Office of Novosibirsk signed an agreement on joint implementation in the city of Novosibirsk innovative project to create a scientific and industrial biotechnology cluster "Farmgorod." The ultimate goal of the formation of the cluster is to create in the city of Novosibirsk leading global center for the development, implementation and production of new drugs and forms. The initial phase of the project is to start in the industrial production of drugs, created by enterprises belonging to the group of companies "Saentifik Future Management", based on the technology of electron-beam synthesis, with the participation of institutes of the Siberian Branch of the Russian Academy of Sciences.

As part of this agreement Company "SPS" made ​​a commitment to the creation of over 5 years of scientific, industrial and educational center with a production potential in terms of money of 30 billion rubles a year, with a view to market about 10 original pharmaceutical products, as well as to 2020 turn from scientific and industrial and educational center in one of the key points of growth in the strategy Mayor of Novosibirsk to create and develop a competitive pharmaceutical and biotechnology industry.

[Flying Hermit]

Could G5 contain milk thistle as it is also used for liver detox and is also telomerase activator?

[Logic]

I am not sure this is a hoax?

http://www.marchmont.../News/2918.html

http://www.scpb.ru/about

http://www.patentbud...NAGEMENT/608573

http://www.linkedin..../Kseniya/Erdman

http://www.patentbud...B5B608/fullview

[Logic]

http://www.scpb.ru/n...8-news-22-11-12

[jans]

creation of the Clinical Center of medical genetic correction and systemic enzyme; http://translate.goo...w.scpb.ru/about Interesting what are they developing.

[Turnbuckle]

It doesn't seem to be a hoax. The company exists, and there are a few patent applications in the world patent office with a number of Russian inventors listed on each. None of the applications have anything to do with longevity, but they are all in the medical field. Here's one such application in the US system--
http://appft1.uspto....OV&RS=ARTAMONOV

[Gerald W. Gaston]

Please pardon the format. It is as was posted. From the notes of Vincent Ocasla (https://www.facebook.com/lordventura):

Siberian scientists test anti-ageing pills on themselves
http://indrus.in/eco...lves_23507.html

Responses

• Timothy John Tiedemann Now the bad news. It's SKQ1. Stick with Ubiquinol. It's already available and cheaper and possibly more effective. It's basically just a mitochondrially targeted form of ubiquinone. Just take enough ubiquinol/ubiquinone which you would do with 200 to 300 mg perhaps and you'll get the same effect. Never trust anyone selling a miracle anti-aging pill.
  17 hours ago · Unlike · 1
• Timothy John Tiedemann A PUFA rich diet is not the greatest diet. Emile Bliznakov also extended the maximum lifespan of middle-aged rats 56% which has never been replicated to that degree but CoQ10 has worked in half the studies on mice, has extended the LS of Drosophila and nematodes. CoQ10 does seem useful in treating some diseases and works better with a reductant like vitamin E. http://www.ncbi.nlm....pubmed/15036411
  
  Coenzyme Q supplementation protects from age-re... [Exp Gerontol. 2004] - PubMed - NCBI www.ncbi.nlm.nih.gov
  
  PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
  17 hours ago · Edited · Like
• Timothy John Tiedemann Animals supplemented on coenzyme Q reached a significantly higher mean life span (11,7% higher, i.e. 2,5 months) and a significantly higher maximum life span (24% higher, i.e. 6 months) than non-supplemented animals. These results suggest that a long-term supplementation with a small dosage of coenzyme Q(10) might represent a good anti-aging therapy in rats fed on a PUFA-based diet.
  17 hours ago · Like
• Mike Lustgarten In contrast,
  
  http://www.ncbi.nlm..../pubmed/9584986
  
  The effects of lifelong ubiquinone Q10 ... [Biochem Mol Biol Int. 1998] - PubMed - NCBI www.ncbi.nlm.nih.gov
  
  PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
  16 hours ago · Like
• Timothy John Tiedemann In comparison. http://www.ncbi.nlm....9456/figure/F3/
  
  Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents www.ncbi.nlm.nih.gov
  
  The effect of the mitochondria-targeted, plastoquinone-containing antioxidant SkQ1 on the lifespan of outbred mice and of three strains of inbred mice was studied. To this end, low pathogen (LP) or specific pathogen free (SPF) vivaria in St. Petersburg, Moscow, and Stockholm were used. For compariso...
  16 hours ago · Like
• Timothy John Tiedemann Here's a comment by Steve Harris on an experiment he ran on CoQ10 and longevity. He used to work with Roy Walford and last I heard was working on Cryonics. "There is a book on CoQ10 by Emile Bliznakov. The stuff is remarkably
  free of side effects. We fed CoQ10 to mice at doses of 1 part in 1000
  in the dry diet (about like 750 mg per day in humans on a percent of
  food basis, and more on a mg/Kg/day basis), and got no toxic effects.
  If anything, the animals on CoQ10 looked a lot better in old age.
  Average lifespan was also improved, but not max life span. This last
  was due to an interesting thing: lymphoma, which is generally a disease
  of young and middle aged mice, was moved out to older ages and killed
  the geriatric mice in the CoQ10 group, something we'd never seen before.
  
  Steve Harris, M.D.
  14 hours ago · Like · 1
• Timothy John Tiedemann Here's a link to a study done by Emile Bliznakov. He never published it in a journal and nobody has replicated it to the extent of an increase in Max LS. http://www.google.co...iw=1440&bih=818
  
  Google www.google.com
  
  Search the world's information, including webpages, images, videos and more. Google has many special features to help you find exactly what you're looking for.
  13 hours ago · Like
• Timothy John Tiedemann http://www.ncbi.nlm....pubmed/19647758
  
  Inhibition of liver fibrosis by solub... [Toxicol Appl Pharmacol. 2009] - PubMed - NCBI www.ncbi.nlm.nih.gov
  
  PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
  13 hours ago · Like
• Mike Lustgarten Here's another paper showing CoQ supplementation did not affect lifespan...
  
  http://www.ncbi.nlm....pubmed/15059645
  
  The impact of alpha-lipoic acid, coenzym... [Free Radic Biol Med. 2004] - PubMed - NCBI www.ncbi.nlm.nih.gov
  
  PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
  6 hours ago · Unlike · 1
• Timothy John Tiedemann Yeah SKQ1 isn't going to do anything that CoQ10 doesn't.
  6 hours ago · Unlike · 1
• Timothy John Tiedemann http://singularityhu...-a-fluke-video/
  
  Did A Russian Scientist Really ‘Cure Aging’ or Is It Just a Fluke? singularityhub.com
  
  Imagine a pill that you could take every day that would extend your by years and keep you healthy for longer. You’d probably pay a lot for such a pill. Vladimir Skulachev looks like he is getting close to selling it to you. The global media has been a flutter [...]
  5 hours ago · Like
• Timothy John Tiedemann (from the above artcle) "Skulachev’s work continues. His anti-oxidant compounds (not sure if this means a new formula or just SKQ1) are being tested in Russia on humans in clinical trials, but as a treatment for glaucoma. I’ve no idea how a mitochondrial penetrating anti-oxidant compound is supposed to cure glaucoma, but there you go. As it would be very hard to test for life extension, such trials are probably only going to confirm safety for the compound. And, of course, whether or not they can cure glaucoma.
  
  Hold on, I just want to take a reality check here. Anti-oxidants that cure glaucoma? That sounds really weird. Most treatments are based on relieving pressure, and some experiments are being done for drugs that affect bloodflow…but antioxidants? These sort of panacea claims don’t lend credence to Skulachev’s work as a whole."
  5 hours ago · Edited · Like
• Timothy John Tiedemann http://www.ncbi.nlm....pubmed/18929135
  
  Rational basis for the development of coenzym... [Prog Brain Res. 2008] - PubMed - NCBI www.ncbi.nlm.nih.gov
  
  PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
  5 hours ago · Like

Edited by gwgaston, 11 April 2013 - 02:55 AM.

[hav]

Might relate to this:

Pharmacological properties of granulocytic colony-stimulating factor pegylated using electron beam synthesis nanotechnologies.
by: Dygai AM, Zyuz'kov GN, Zhdanov VV, Madonov PG, Udut EV, Miroshnichenko LA, Khrichkova TY, Simanina EV, Stavrova LA, Artamonov AV, Bekarev AA, Kinsht DN, Chaikovskiy AV, Markova TS, Gurto RV.

Granulocytic CSF pegylated using electron-beam synthesis nanotechnology exhibits pronounced granulomonocytopoiesis-stimulating and SC-mobilizing activity. More potent stimulation of committed precursors against the background of less pronounced activation of polypotent hemopoietic cells is a peculiarity of hemostimulating action of pegylated using electron-beam synthesis nanotechnology granulocytic CSF in comparison with its non-modified analog. The mobilizing effect of pegylated using electron-beam synthesis nanotechnology granulocytic CSF on early progenitor elements surpasses that of non-conjugated cytokine.

Seem to be quite a few stem cell papers coming out of Russia that mention electron-beam synthesis nanotechnology.

Howard

[Andey]

Another article on Russian
http://translate.goo...e-dlya-pechati/

and another one
http://translate.goo.../#ixzz2BhcQKMO6

IMHO this diint look like Hoax, using LINACs for hoaxes is kind of overkill )

Edited by Andey, 12 April 2013 - 01:03 PM.

[Andey]

They already started sales of "DNA Karma" supplement based on G5 research
http://dnasl.ru/dna-karma.html
Information is incomplete but from one interview I found that declared effect is 30-40% increased production or profiliation of stem cells (they use expression 40% increased output - I dont know what does it mean in this context )) )
Cost is about $120 for 10 capsules what is supposed to take 1 in few days time.

I need to say that company business is in supplements production with strange sales strategy similar to MLM. I dont really trust them but...who knows ? )

Added: Found this DNA Karma video presentation on youtube
Dont usefull really unless you know russian )) but here is picture comparison of rats sclerosis liver - without and with treatment for 40 days
https://www.youtube....Cfko5yE#t=1990s
Quite impressive, but I have some doubts about metodology used - why dont they use simply comparison before and after treatment ?

Edited by Andey, 07 June 2013 - 02:56 PM.

[YOLF]

So is this stuff for real or is it just SKQ1? AFAIK SKQ1 is only available as an eyedrop, and only in the moscow area. Are supplements required to have their active ingredients etc. printed on them in Russia? I don't see the "nutrition facts" part of the lable that usually accompanies supplements sold in the US.

[Andey]

So is this stuff for real or is it just SKQ1? AFAIK SKQ1 is only available as an eyedrop, and only in the moscow area. Are supplements required to have their active ingredients etc. printed on them in Russia? I don't see the "nutrition facts" part of the lable that usually accompanies supplements sold in the US.

This stuff is nothing to do with SKQ1. There are not one laboratory in Russia and as far I understand Skulachev is no way connected to this ))

You are right, there is no proper ingredients list.
Instead of ingredients they wrote something like part 1: - some oligonucletiodes, part 2: some protein mix.
Even for Russia standarts it looks like BS.

Suprisingly enough I am seriosly consider to purchase this stuff. My father have a serious liver condition and even if there is a 10% chance it could help I will give it a try.

Edited by Andey, 15 June 2013 - 05:02 PM.

[YOLF]

You should give him C60 EVOO... Have you seen the level of protection it can give a rodent liver? I'd love to see a human case studies on C60 for liver conditions.

Maybe someone who has purchased it can post a picture of the ingredients list from the container and translate it for us (and provide text in Russian so we can translate it on our own to confirm). The Newspaper looks pretty legit, I always love the Russian perspective on things, the really juicy parts of the news get hijacked here by passionate "inherent righteousness" debates.

Edited by cryonicsculture, 16 June 2013 - 12:32 AM.

[Andey]

You should give him C60 EVOO... Have you seen the level of protection it can give a rodent liver? I'd love to see a human case studies on C60 for liver conditions.

Maybe someone who has purchased it can post a picture of the ingredients list from the container and translate it for us (and provide text in Russian so we can translate it on our own to confirm). The Newspaper looks pretty legit, I always love the Russian perspective on things, the really juicy parts of the news get hijacked here by passionate "inherent righteousness" debates.

Of course I gave him C60oo but, honestly, saw no difference. Some drugs works noticably for him but this is not a case with C60oo.
I will buy it but dont expect any additional labeling. Supplements is almostly unregulated in Russia and this is a good example of this. They pushed to supplement market substance that at the same time they claim is on studying and proving process on the way to became registred drug. I still dont know is it available in Ukraine though.

Edited by Andey, 16 June 2013 - 05:39 AM.

[drtom]

As someone who has spent 10 years in Russia I say this:
Be VERY careful with anything coming out of that country.
All rules go out window. All bets are off.
It is "Caveat Emptor" on a grand scale.