After two rounds of oral antibiotics and many health supplements I still having issues with chronic bacterial prostatitis.
I was surprised to see that the antibiotics helped a lot with my chronic fatique and brain fog. Searching on line I found a corellation with bacterial prostatitis and chronic fatique, more so than other chronic infections, anyone having the same experience? Its the third day off the antibiotics and relapsing hard...
Anyway, I am looking at EDTA for its biofilm busting properties:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1393226/
"Biofilms consist of groups of bacteria attached to surfaces and encased in a hydrated polymeric matrix. Bacteria in biofilms are more resistant to the immune system and to antibiotics than their free-living planktonic counterparts. Thus, biofilm-related infections are persistent and often show recurrent symptoms. The metal chelator EDTA is known to have activity against biofilms of gram-positive bacteria such as Staphylococcus aureus."
There is quite some research on the biofilm busting properties of EDTA and I am searching what is the best way to use it. Oral bioavailability is very low, IV its very expensive and has the extra hassle of many doctor visits, and suppositories are still expensive, especially if you need to take it for months, as is the case when you have a chronic infection.
Reading some reports from online forums specifically for chronic bacterial prostatitis, it seems that EDTA suppositories, worked together with antibiotics (synthetic and natural) when nothing else worked.
The penetration of EDTA in the prostate is good.
http://healthydoctor...ostate-disease/
What I am trying to figure out is how to best use EDTA, or maybe recreate this expensive suppository.
http://www.detoxamin...w&id=4&Itemid=7
It seems very expensive considering the main ingredient (Calcium Disodium EDTA) for the amount listed would be a few $ in ebay.
There are two issues I am puzzled. First, I received a 100gr of pharmaceutical grade EDTA from ebay yesterday, the time I ordered it, I did not know that this specific brand was using Calcium Disodium EDTA, and not the one I ordered it.
http://www.ebay.co.u...=item1e75897c4a
My chemistry knowledge is very limited, no idea what is the base in the one I ordered. In any case I measured 1 gr of it, dissolved it in 30ml of warm water, let it cool and use it as an enema. The problem is that this stuff is very irritating, I thought that my issue is with the specific chemical I order and the calcium base would be OK but I was reading that this its irritating also. I am quite puzzled now, how detoxamin uses 1gr Calcium Disodium EDTA in their suppositories with no irritation?
Second thing I am puzzled is that I am reading that EDTA is not oil soluble, but they use a cocoa butter base?
In any case I found that magnesium EDTA is not irritating and is listed on ebay for a few $ also, but I am wondering if the chelating and biofilm busting properties are the same.
Any ideas?