More anecdotal reports from the Epitalon thread:
Gramson:
...tremendous benefits with ghk cu. I also think this helps increase T4 cells in exposure to HIV. My friend is sexullay active and had exposure to HIV, seen in low t4 count. I gave4 her ghk cu, and the count is up. willl follow up...
http://www.longecity...ndpost&p=748652
dz93:
...Also, about GHK-Cu. I've learned that the effects of GHK-Cu are potentiated by ascorbic acid. I've also learned that GHK-Cu + Thymogen + Dalargin enhanced bone healing. Based on this, I will dose ascorbic acid when I dose GHK. I will also be purchasing Thymogen/thymalin and epitalon Amidate. Since studies have shown that thymalin and epitalon go well, I'd imagine GHK-Cu + Thymalin/Thymogen + Epitalon would go great together. Once I get all those, I'll report on whatever effects I notice from taking them together. What are your thoughts on this?...
http://dx.doi.org/10.1155/2015/648108
http://www.longecity...ndpost&p=748656
...Its not anecdotal. Its briefly mentioned in the source I posted. I'm unsure of how much Ascorbic Acid potentiates it and when I dosed the two together I did not notice an increase in effects but I only say that because anything I did notice wasn't significant enough for me to believe the ascorbic acid had any immediate effect. The only thing I can say about that is I tried it when I was intentionally using GHK to heal a bad wound and I did notice a slight increase in healing speed and it healed much better than it normally would have. I drank some orange juice (made from 8+ fresh oranges) and injected 25mg of GHK. I also used a concentrated (~50mg) amount applied directly on the wound itself.
So, I want to say that my experience with GHK and ascorbic acid is extremely anecdotal and I can't rule out the placebo effect yet. Unfortunately, I wasn't able to tell if direct application better helped with healing when compared to injection. Basically, I can't offer anything of use right now haha. All I can say is that, based on the few days I tried it, GHK seems to work slightly better when taken with ascorbic acid. I'd go for natural sources instead of supplementing...
http://www.longecity...ndpost&p=750843
...I want to share as much of my experiences as possible so I can help draw attention to GHK but at the same time I really don't want to be too detailed due to confirmation bias. However, since GHK has such broad effects, I'd imagine the experiences will greatly differ. For example, I must have had poor gut health which is why I had experienced diarrhea initially. As I continued to take it, that side effect had greatly diminished and my guts felt much better than before. I have yet to hear of anyone else reporting diarrhea as a side effect. So it is my assumption that the effects will greatly vary among people...
http://www.longecity...ndpost&p=750853
Rocket:
Here is my log of GHK:
Day 5 of 25mg/day every morning. No results.
http://www.longecity...ndpost&p=750858
"The effects of GHK-Cu are potentiated by ascorbic acid" wrung a bell:
Me:
L-threonate represses the glycoprotein dickkopf-1 (Dkk-1) via alkaline phosphatase activity; releasing ascorbic acid into the cell.
This enhances neurogenesis in the hippocampus, and stops papilla cells from dying and the hair-producing outer root sheath cells from stopping to work.
So perhaps we get the same amount of Magnesium from the L-Threonate form as any other, but its the vitamin C inside the cell, causing neurogenisis, that adds the extra brainy effect.
Ukko:
1. Problem: Vitamin C in the ascorbic acid form does not cross the BBB to brain. Traditionally, it was thought that it was the dehydroascorbic acid form how vitamin C got to the brain. Using glucose transports given the similarity between glucose and Vit c chemically. http://www.ncbi.nlm....cles/PMC508490/
2. Vitamin C is hugely important for brain function. We should all know that low brain vitamin C leads to low dopamine. Uncool, don't want that. What is also known is that vitamin C is needed for healthy BDNF production. Lots of studies on that...start from here: http://www.ncbi.nlm....pubmed/15627972
3. How does Mg threonate fit into the picture? Well, its other part is threonic acid a molecule closely related to ascorbic acid. In fact, its breakdown product. Put there is increasingly data on threonic acid being able to do whatever ascorbic acid does, even preventing scurvy the classic syptom of vitamin C deficieny. Irrelevant whether threonic acid can actually be converted back to ascorbic acid or whether when we speak of scurcy and vitamin C deficiency, we are actually talking about threonic acid deficiency. Guess what? Threonic acid is up to 4 times better as vitamin C than ascorbic acid itself in that it prevents scurvy four times better than ascorbic acid. Wow. http://www.immunesup...ws/94spr002.htm It also hugely boosts cell uptake of ascorbic acid, maybe this is the mechanism. But it does not matter. Threonic acid makes the vitamin C metabolism work vastly better and it crosses over to brain through the BBB, at least when bound to a mineral like magnesium.
http://www.longecity...osteoarthritis/
Edited by Logic, 11 November 2015 - 01:36 PM.