Parnate (tranylcypromine) its a very effective antidepressant, almost every drug rating site has it as a treatment for depression at the top... There are experiences at times like this...
"I have been treated for severe cyclic depressions (atypical), anxiety, and OCD since college and I am 47. Without effective medication, my illness is debilitating. In 1993, after trying many different antidepressants, I urged my psychiatrist to prescribe me the monoamine oxidase inhibitor, Nardil. WOW....somebody switched the lights on and the symptoms off. 90% of the time I was in remission with only brief minor periods of symptoms. Nardil was reformulated and stopped working, so I switched to Parnate. 160mg/day give 100% symptom relief (with 1200mg/day lithium). I mentally feel like I'm 20, bursting with mental energy. Many considered me brilliant prior to Parnate; but after years on it, my cognitive skills, retention, and creativity reached a new level."
Although tranylcypromine is not a new drug, is difficult to get a prescription for it, the reason is that you have to follow strict dietary restrictions in order to avoid side effects, the most serious being hypertension. The risk of hypertension depends on the deactivation of MAO (that breaks down tyramine) when the tranylcypromine reaches the stomach. Eating high tyramine foods that does not brake down in the stomach, brings tyramine to the brain that releases and takes the place of norepinephrine giving a sudden spike in blood pressure. If oral use of tranylcypromine did not have this side effect would probably be the most popular antidepressant. My idea is to buy the pure chemical and change route of administration in order to avoid the deactivation of MAO in the stomach. This can be done making a tranylcypromine nasal spray or just use it sublingually.
If there is interest for a very small group buy I found an American lab for the hemisulfate salt of tranylcypromine for a relatively good price of $405 / 5 grams without shipping. Although I got a prescription from a doctor that is a friend and trust me to follow the dietary restrictions, I ll prefer to get the pure chemical. I am interested for 1 gram (at least) we also going to need another long-term member placing the order having a VAT# other than that I got the impression that would not be difficult to acquire it from the link below.
http://www.scbt.com/...lcypromine.html