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              Advocacy & Research for Unlimited Lifespans

Chris Linnell's Longevity Review Newsletter



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December 2022 Longevity Review

Posted by Chris Pollyanna , 04 January 2023 - - - - - - · 1,073 views
supplements, fasting, nad+, nmn and 1 more...
As we end another turbulent year, the longevity field thankfully continues to see more steady progress, highlighted by rejuvenated blood stem cells extending lifespan, a new improved epigenetic clock, mole removal via senolytics, and young plasma and microbiomes improving various health parameters.  Meanwhile, in the exercise section, if you’re lo...


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November 2022 Longevity Review

Posted by Chris Pollyanna , 08 December 2022 - - - - - - · 984 views
supplements, rapamycin, fasting and 5 more...
There seems to be an issue occurring when I try to post this entry. Almost all of it has been cut off. While I wait for admin to fix this issue, you can read it on my Patreon site: 
https://www.patreon....r-2022-75669692  
Apart from the first results of my n=1 rapamycin trial, this month you’ll find senolytics for skincare and ra...


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October 2022 Longevity Review

Posted by Chris Pollyanna , 10 November 2022 - - - - - - · 1,191 views
supplements, rapamycin, metformin and 6 more...
Another month, another set of advances in the field of longevity including the publication of perhaps the most important paper of the year - showing synergy between senolytics and partial epigenetic reprogramming. More advances involved the use of extracellular vesicles, probiotics, and in the supplemental section astaxanthin showed benefits as well as...


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September 2022 Longevity Review

Posted by Chris Pollyanna , 17 October 2022 - - - - - - · 1,060 views
supplements, rapamycin, metformin and 5 more...
After last month’s blockbuster, there was a slight slowdown in the longevity field as the summer wound down and the leaves contemplated their journey earthwards. As a counterpoint to August’s plasma dilution lead item, a study came out this month showing the reverse with the use of umbilical cord plasma concentrate giving a small reduction in GrimAge. Vy...


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August 2022 Longevity Review

Posted by Chris Pollyanna , 10 September 2022 - - - - - - · 1,762 views
supplements, rapamycin, nmn, nad+ and 6 more...
So much for the dog days of summer - after a fallow July, August was a blockbuster month in the longevity field with the first human results for plasma dilution therapy, a placebo controlled trial showing benefits for GlyNAC, and a potential breakthrough for epigenetic reprogramming. And that’s just scratching the surface!  In the supplemental sec...


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July 2022 Longevity Review

Posted by Chris Pollyanna , 04 August 2022 - - - - - - · 1,470 views
rapamycin, nmn, resveratrol, nad+ and 4 more...
As the dog days of summer are upon us, and productivity takes a nosedive in the sweltering heat (OK, maybe that’s just me!), it appears that there has been a spillover effect in the longevity field with not many exciting breakthroughs to choose from for the Round Up. However, having said that, there were of course still plenty of interesting results. Apar...


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June 2022 Longevity Review

Posted by Chris Pollyanna , 11 July 2022 - - - - - - · 1,630 views
nmn, nad, curcumin, reseveratrol and 4 more...
Welcome to a slightly truncated Longevity Review. As I started putting this together, I came down with COVID for the first time, which has set me back several days. I’ve recently been feeling that I’m falling behind where I want to be with the CLA and want to change that, so I will keep the written portions of this review brief and let the studies speak f...


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May 2022 Longevity Review

Posted by Chris Pollyanna , 09 June 2022 - - - - - - · 1,590 views
nmn, nad+, rapamycin, metformin and 6 more...
Another month, another step towards our longevity future, with plenty of advances to showcase. In the Round-Up you will find a human trial of a new supplement, a novel combination of drugs, gene therapy and more. There are also some more human results with Glucosamine, NMN, Metformin and others. Unfortunately, there was a disappointing human trial resu...


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April 2022 Longevity Review

Posted by Chris Pollyanna , 11 May 2022 - - - - - - · 1,708 views
supplements, rapamycin, nmn, nad+ and 4 more...
Although not as crazy as March, April nonetheless trumped March by producing the preprint paper I’ve been waiting a long time for - the combination of two major longevity modalities for the first time: senolytics and partial-reprogramming. I’ve said it a thousand times and I’ll say it several thousand times more: we will only make a large impact on ageing...


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March 2022 Longevity Review

Posted by Chris Pollyanna , 06 April 2022 - - - - - - · 1,715 views
supplements, fasting, nmn and 6 more...
March Madness! There was such an abundance of great studies out in March that my head is still spinning, and made for some nice tricky selection decisions for this month’s Round-Up. For example, there were several interesting senolytic studies including another human result and, just like buses, three exciting reprogramming papers, along with three new li...






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