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Fight Aging News
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Nuclear Lipid Droplets as a Hallmark of Aging
Abnormal localized excesses of lipids in tissues,...
Today, 11:22 AM Read Full Story -
Inflammation as an Important Mechanism in the Role of Growth Hormone in Aging
Interfering in growth hormone signaling has been...
Today, 11:11 AM Read Full Story -
BioAge Labs Announces Multi-Year Collaboration with Novartis
BioAge Labs, Inc. (“BioAge”), a clini...
Yesterday, 09:38 PM Read Full Story -
Transcriptional Trajectories of Aging in Nematode Worms
What can we learn about aging from mutations that...
Yesterday, 07:29 PM Read Full Story -
Lower Rates of Epigenetic Aging in Olympic Champions
A recent investigation into Hungarian Olympic cha...
Yesterday, 05:03 PM Read Full Story -
Delivery of Platelet Factor 4 Rejuvenates Hematopoietic Stem Cell Function
Platelet factor 4 (PF4) has been the subject of i...
Yesterday, 11:22 AM Read Full Story
Articles Archives
8 Reasons to reach out to 'the public'
While the idea that drastic life extension may be an option for humankind in the future has been encountered by many through the media and fiction, the vast majority of the public do not grasp whether and how this could realistically apply to them or t...
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Pioneers: Marquis de Condorcet (1743-1794)
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Eternus by Neurohacker Collective
A 36 Ingredient Formula for Comprehensive Cell Energy & Aging Support
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Why do some turtles outlive humans?
by Vit Zemanek
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'Nugenics' - breakthrough rejuvenation?
Discussion of a recent preprint by Horvath/Katcher et al. reporting rejuvenation in mice with an undisclosed blood component.
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Cryonics
The following is a quick overview on Cryonics. NB: The information below is periodically reviewed for accuracy, but LongeCity makes no representations or gives any warranties whatsoever that the following information is accurate and complete at an...
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Aging Theories: is an 'aging program' a...
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Antioxidants- relevant for life extension?
by Vit Zemanek
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Metformin - a geroprotector?
Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information...
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Geroprotector Review: Rapamycin and other mTOR...
Sven Bulterijs continues his discussion of prominent compounds with potential life extension efficacy by looking not just at rapamycin but also at its target, the mTOR pathway, which has likely a key role in mediating lifespan. ⇒ read the article i...
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Nootropics in human trials (Intro)
by Lukas
Due to further advances in the field of neuropharmacology new possibilities of cognitive self-enhancement emerge.
Some are marketed as ‘smart drugs’, cognitive enhancers or nootropics.
This article aims to provide a brief overview.
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Aging theories: Is there a unifying factor in a...
by: Vit Zemanek
- evolutionary approach to the process of senescence
- programmed theories of aging
- error theories of aging
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Assessing the effects of c60 on human cancer pr...
View attachment: c60re02.png "Assessing the effects of c60 on human cancer proliferation in vivo"is led by life-extension trailblazer Kelsey Moody. It is interesting that he turns the attention of his new venture Ichor Therapeutics to...
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Supplement Review: Nicotinamide Riboside
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Aschwin de Wolf: Cryonics
(interview Feb. 2017)
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Article: Gut microbiome in health and aging
As part of his new column "Sven's Science Corner" Sven Bulterijs discusses novel insights into the crucial role gut bacteria seem to play in health, disease and aging. ⇒ read the article in "Sven's Science Corner" blog
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Honorary Member: Fred Chamberlain (boundlesslife)
View attachment: fred.jpgIn the early 1970's Fred Chamberlain, together with his wife Linda founded the cryonics corporations Manrise and the Alcor Society for Solid State Hypothermia, The latter continues until today as the Alcor Life Extension Foun...
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LongeCity Science Initiatives - Autumn 2011 review
“To conquer the blight of involuntary death” is a complex task: political, economic, logistic, and social factors all play a role in making this dream a reality. Ultimately though, the challenge remains a scientific and technological one. We need to kn...
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"Healthy Aging" is not enough
A Response to the "Compression of Morbidity" Mindset "...there is no basis for the ardent hopes and positive statements made as to [its] safety and success[..], and [..] therefore, it would be a wrong, whet...
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crowdsourced multivitamin
Extending maximum human lifespan will likely require a wide range of new biotechnology. Powerful interventions such as pharmaceuticals, stem cell technology, and gene therapy are in development but could be years or decades away from widespread impleme...
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Carbon nanospheres almost double rat lifespan:...
by AgeVivo and Sven Bulterijs more discussion of the paper in question in this thread in the C60 Health sub-forum this article is a work in progress, it may change over time based on discussions and new information / Introduction In June of 2012...
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Metformin a life extension drug?
by Sven Bulterijs For hundreds of years it has been known that a plant extract from the French lilac (Galega officinalis) improved the intense urination seen in diabetes patients. From this plant guanidine was extracted but it was too toxic for human u...
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Folding@Home Team
Use your computer's spare processing power to help cure disease!TheLongevity Meme has teamed up with Longecity to contribute to the Stanford Folding@Home distributing computing project – aimed at curing disease through understanding the basics of prot...
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Calorie Restriction Primer
by Sven Bulterijs & Paul McGlothin, Often described as the only proven intervention that extends mean and maximal life-span in mammalian species, it is also a lifestyle choice for the committed immortalist. But why and how does it work? How to begin...
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Crosslinks
by Johan Sjöberg The diseases and complications of aging are infamous –cardiovascular disease, cataracts, Alzheimer's disease, amyloidosis, cancer, and so on. Their effects are often debilitating, and one of them will always end up causing your death...
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