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Fight Aging News
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Prevalence of Specific Gut Microbial Species Associated with Muscle Mass in Later Life
16S rRNA is a gene that varies in sequence distin...
Today, 06:19 PM Read Full Story -
Study Suggests Alzheimer’s Prevention by Anti-Amyloid Drug
According to an open-label study from Washington...
Today, 04:00 PM Read Full Story -
LAMP1 as a Cell Surface Marker of Senescent Cells
Cell surface proteins distinctive to senescent ce...
Today, 10:22 AM Read Full Story -
Elamipretide / SS-31 Improves Muscle Function But Doesn't Affect Epigenetic Age
Elamipretide was formerly known as SS-31, and is...
Today, 10:11 AM Read Full Story -
Circulating Citrulline Declines with Age, and Supplementation is Anti-Inflammatory in Mice
Reminiscent of recent work on supplementation of...
Yesterday, 06:22 PM Read Full Story -
Joshua “Scotch” McClure: “Infectious Disease Drives Aging”
Like many people, I’m both wary of and intrigued...
Yesterday, 04:00 PM Read Full Story

Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles

Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information ⇒ read the article in "Sven's Science Corner" blog
1 Comments
Here is an interesting study about using leucine with a reduced dose of metformin.
Ok it's a mouse study but I also saw a human study showing the same thing. I think
they were finding about 400mg of leucine and 125 mg metformin 3 times a day was
as effective as 500mg metformin 3 times a day for lowering blood sugar.
https://www.ncbi.nlm...pubmed/25858853