ImmInst Active Topics Last Updated: 21 November 2024 - 09:58 AM

https://www.youtube.com/watch?v=UF8UE6cJaWQ&t=1s

I explored why the habits that extend life—like walking and exercise—often fail to show up in blood test results. Here’s what I found:

• Big Impact, Small Biomarker Change: Walking 12,000 steps daily can add up to 10 years to your life, yet it barely impacts standard blood tests.

• Proven Habits: Combined, regular aerobic exercise, HIIT, and strength training add up to 24 years to your lifespan, despite minimal effect on biomarkers.

• Glucose Reality: Mortality risk stays flat between 75-100 mg/dL, making glucose optimization less meaningful than we think.

The takeaway? Focus on consistent, life-extending habits rather than chasing perfect bloodwork.

Read more about why habits matter most: https://www.unaging.com/beyond-biomarkers/

https://www.youtube.com/watch?v=rvLJGFQxbjc

Here are two photos of William Shatner. The one on the left is from 1978 when he was 47. The one on the right is from 2011 when he was 80. He looks much younger at 80 than at 47. He does seem to have reduced in age-appearance significantly. I have not been able to find out what his diet consists of or if he takes supplements.

Hi everyone, 

I'm looking to see if anyone has had experimenting with Mifepristone to re-sensitize their cortisol receptors to cortisol. I developed a series of health issues after a prolonged period of long term stress. I know mifepristone could help me, and actually saw a couple people on here that reported great success as well!

Does anyone have an experience with this, or know where I can get Mifepristone?

Thanks,

joseph

Hi all,

I thought I'd introduce myself. My name is Joseph and I'm most interested in studying the HPA axis. Because that's what I myself have problems with. 

I'm going to attempt to reset my HPA axis with Mifepristone, but I need to find a source first! If anyone is has one, please let me know!

Thank you,

Joseph

Ok I decided to give this medication a try for general anxiety. I was prescribed 10 mg of Buspirone twice a day and started taking it two days ago. To my understanding it takes 2-4 weeks for full effects. I feel some mild lightheadedness after taking it but no other side effects yet.

Something to watch out for with this medication? Successful anecdotes?

I did a quick search and it seems some take it up to 60 mg a day. I may ask for dose increase after few weeks if it doesn't seem to work?

Wondering how aerobic exercise truly impacts your lifespan? Here’s what the research clarifies:

• Front-Loaded Benefits: Running just 30 minutes once a week can cut all-cause mortality risk by 30%.

• Diminishing Returns: Jogging more than 6 hours a week doesn't further lower mortality rates, but faster paces may provide additional gains.

• Mitochondrial Efficiency: Regular aerobic exercise boosts mitochondrial density, improving oxygen conversion and energy output.

Learn how strategic, minimal exercise can maximize longevity without overexertion.

Read the full analysis: https://www.unaging.com/exercise-and-longevity/