Yes but what you are missing is that after you do the sublingual thing you still swallow the NMN which is then absorbed by the intestines. So you get whatever amount is absorbed sublingually + whatever is absorbed in the stomach and intestines. Really there is no down side to doing sublingual.
I had encouraged everyone to research the scientific trial conducted by Joshua Rabinowitz, Phd who is a personal classmate and friend of Dr. Attia. No one did so. I am posting it here so everyone can digest it's implications. Also, read and listen to my previous post from Dr. Attia.
http://sci-hub.tw/ht...met.2018.03.018
What they did in the trial was label NAD precussors and NAD with isotopes so they could follow them in the body after ingesting them orally. They proved that none of the tested substances made it past the liver. You are not going to get much better evidence that this study of the futility of taking NAD or it's precursors orally and expect any increase in NAD in the mitochondria. There will be some who will try and attack solid evidence and facts such as these, but they are the same that preached that the world is flat, inoculations don't protect against viruses, and that antibiotics do not kill bacteria infections. As, I pointed out in my previous post that Dr. Attia had come to the conclusion after talking with his research colleagues that NAD and it's precursors when taken orally do not every make it to the cells where they really need to be. While sublingual and IV will get the NAD precussors where they need to be, taking NAD either orally or subliminally is a waste of money. According to the real experts, NAD cannot be taken up by the mitochondria, but has to be manufactured in the cell. So precursors are the way to go. I personally will continue to follow this advise until a more concrete study is published refuting these facts. And they are facts, not theory.
ABN wants to continue selling NAD and NMN, but if I was going to purchase one it would be the sublingual NR which ABN does not sell because of the taste. One can manufacture there own with N+R, with no bad taste. In the above cited trial under "Conclusions", " Surprisingly, i.v. NR was much more effective than NMN for labeling the NAD pool in the skeletal muscle. This is consistent with the proposal that at least some tissues are incapable of taking up NMN directly (Ratajczak et al., 2016; Nikiforov et al., 2011)." As far as the amount of the sublingual dose that makes it into the blood stream, all I know is if a person takes a nitroglycerin tablet under there tongue they get an almost immediate response. I'm sure there are studies on sublingual dosing, but will have to research.
Edited by PAMPAGUY, 11 March 2019 - 07:56 AM.