10 replies to this topic

[Jesuisfort]

Hello, do you know any supplement or something like that , that can  improve  emotion for music ?  and for movie , video games ...

 

I heard about piracetam, what do you think ?

[Galaxyshock]

Usually it's only the more recreational substances that induce enjoyment. So you're most likely looking at stimulants. I find Kava to make make me enjoy music more though.

[Keizo]

Cerebrolysin the first 1-2 days of starting a cycle, at 5ml/day or so. I think racetams are trash, but they probably do something with music. PLR-853 is another suggestion, although I think that's basically a mild stimulant.

Anyway these things (improved mood that is very significant and obvious) I would think are almost always temporary and not sustainable. Regular prescription stimulants probably work quite well, but that's more in an analytical sort of way IME, things become more bearable and interesting.

Edited by Keizo, 04 April 2018 - 08:47 PM.

[Ruth]

Palmitoylethanolamide+Phenylalanine with curcumin.
https://www.frontier...2015.00006/full Endocannabinoidergic and opioidergic enhancement without direct reward activation.

https://www.scienced...043661816303917 Social play behaviour is a vigorous form of social interaction, abundant during the juvenile and adolescent phases of life in many mammalian species, including humans. Social play is highly rewarding and it is important for social and cognitive development. Being a rewarding activity, social play can be dissociated in its pleasurable and motivational components. We have previously shown that endocannabinoids modulate the expression of social play behaviour in rats. In the present study, we investigated whether endocannabinoids modulate the motivational and pleasurable properties of social play behaviour, using operant and place conditioning paradigms, respectively. Treatment with the anandamide hydrolysis inhibitor URB597 did not affect operant responding or social play-induced conditioned place preference (CPP) when administered at a dose (0.1 mg/kg) known to increase the expression of social play behaviour, while it modestly reduced operant responding at a higher dose (0.2 mg/kg). The cannabinoid-1 (CB1) receptor antagonist rimonabant reduced operant responding when administered at a dose (1 mg/kg) known to decrease the expression of social play behaviour, although this effect may be secondary to concurrent drug-induced stereotypic behaviours (i.e., grooming and scratching). These data demonstrate that enhancing endocannabinoid levels does not differentially affect the motivational and pleasurable aspects of social play behaviour, whereas CB1 receptor blockade reduces the motivational aspects of social play behaviour, possibly due to response competition. Thus, endocannabinoids likely drive the expression of social play behaviour as a whole, without differentially affecting its motivational or pleasurable properties.
Neuropsychobiology. 2016;73(2):123-9. doi: 10.1159/000443890. Epub 2016 Mar 25.

Prohedonic Effect of Cannabidiol in a Rat Model of Depression.

Shoval G1, Shbiro L, Hershkovitz L, Hazut N, Zalsman G, Mechoulam R, Weller A.



Author information


Abstract

BACKGROUND:

Accumulating evidence suggests that cannabidiol (CBD) may be an effective and safe anxiolytic agent and potentially also an antidepressant.

AIM:

The objective of this study was to further examine these properties of CBD using the 'depressive-like' Wistar-Kyoto (WKY) rat, focusing on the drug's effect on anhedonia-like behaviors.

METHODS:

Forty-eight WKY and 48 control Wistar adult male rats were pretreated orally with CBD (15, 30 and 45 mg/kg) or vehicle. The saccharin preference test (SPT), the elevated plus maze (EPM) test and the novel object exploration (NOE) test were used.

RESULTS:

CBD showed a prohedonic effect on the WKY rats at 30 mg/kg in the SPT. In the NOE, CBD increased exploration of the novel object and locomotion at 45 mg/kg and increased locomotion at 15 mg/kg, indicating an improvement in the characteristically low motivation of WKY rats to explore. There was no similar effect at any dose in the EPM or in open-field behavior in the habituation to the NOE.

CONCLUSIONS:

These findings extend the limited knowledge on the antidepressant effect of CBD, now shown for the first time in a genetic animal model of depression. These results suggest that CBD may be beneficial for the treatment of clinical depression and other states with prominent anhedonia.

© 2016 S. Karger AG, Basel

Edited by Ruth, 04 April 2018 - 10:27 PM.

[BlueCloud]

Sitting comfortably in the dark with good sounding headphones on your head , and playing music you really enjoy , is still the best way to augment the emotional experience of music.. A tiny bit of alcohol may help, but I think that too much of anything that alters you will make you think Rick Astley's "Never Gonna Give You Up" is a musical masterpiece. 

 

Listening to music, and I mean really listening, not doing something else at the same time and multitasking, is becoming a lost art.

 

Edited by BlueCloud, 06 April 2018 - 08:03 PM.

[baccheion]

Oxiracetam (+ aniracetam). Aniracetam + coluracetam.

[dojob]

cerebrolysin, NSI 189 and of course--> a tiny dose of weed, shrooms or lsd

[dopaminerush]

Sulbutiamine

 

30-120mg pseudoephedrine + 1 hour later strong coffee

 

if you are responding very well, SSRIs  can make you enjoy music even the kind you never listened before and hate. This is because its anti-anhedonic, neuroplasticity and other effects. thye are freeing your mind. but their effects will kick in after weeks.

 

 

[AOIministrator]

Yeah, NSI-189 is basically like mild shrooms without any hallucinogenic effect and improved instead of impaired cognitive ability.

[Hyperflux]

Phenylpiracetam + alpha GPC, bromantane, tianeptine sodium, NSI-189, ETH-LAD, 4-HO-MiPT, caffeine, dextroamphetamine, pramipexole, phenibut.

[bellaalice]

The music is amazing and brings people together. You can download melodies as tonos de llamada gratis for your phone more interesting.