Hello, folks. My scores for the Rotation test on Cambridge Brain Science has been up ~ 30-40% over the past couple of days. Yes, there are confounding elements, and maybe the community could chime in with observations or possibly attempt to reproduce such a significant increase given the changes described below.
More specifically, my range of scores over the past 4 months had steadily increased from month 1-3 and have topped out in the last month around 170. Based on whatever influence is at play I've been able to consistently get a score in the 220 range with a max of 244 over the past two days. I felt it important to test in the AM on day 2 without being under the influence of two new suspect supplements I recently received as a control. I didn't sleep well the night before and not having dosed my score fell back to 110.
Here's what has not changed.
Doxepin 5-10mg nightly for insomnia
Tylenol 650 mg extended release nightly
Melatonin 3 mg nightly
Methylene Blue 1 mg mornings
Here's what has changed.
Lion's Mane 1.5g nightly - Reinstatement after about a month with a new brand (Real Mushroom)
Afobazole 5 mg ~ 2 hours prior to testing on occasion of high scores
Galantamine 2 mg ~ 2 hours prior to testing on day 1 with the new high score
Ibuprofen 200 mg nightly
The Cambridge Science site has recently undergone a facelift and all baseline test results were gained prior to the revamp.
So, ...this gain on the rotation test doesn't quite make sense to me. I would have never expected either Afobazole or Galantamine would have such a significant impact - and I kind of doubt it. I'm starting to wonder if Cambridge Brain Science site has been updated with a new algorithm that controls the rotation test - and that the test is now easier. It's hard to tell just looking at the patterns if there has been any reduction in difficultly.
So, I started looking at brain centers responsible for mental rotation performance. This would be the right parietal lobe. I then began to try to dig up any research on the effects of dopamine, sigma activity (Afobazole) and ACh/E I activity as it relates to the parietal lobe. No clear reason why my rotation test scores would be up.
Obviously, I need to extend this testing out over a few more weeks to firm up the results being on/off the new supplements. Still, I haven't experienced this major (upward) variability with the tests before and thought it was worth throwing it up on here for comment.
Rotations_afobazole_and_galantamine_20180523.png 79.25KB
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Edited by lrdmelchett, 23 May 2018 - 07:41 PM.
