2 replies to this topic

[Forever21]

This two-pronged effect whereby excitatory signaling is enhanced and gabaeric signaling is suppressed raises questions about the potential neurotoxicity of modafinil in combination with other allosteric modulators of glutamate receptors, such as the racetams. http://www.focuswish...nism-of-action/

[John250]

I’ve heard people say that Modafinil can actually weaken the effects of amphetamines so not sure what it’s effect would be on racetam nootropics.

[modafinilneo]

Combining is a tricky matter... This one seems safe, though, as long as you stick with low doses of each.