The best evidence you will have is your personal experience. Unfortunately, most pharma and supplement studies concentrate on daily dose regimens. Through observation of the deep root of this paradigm, I offer that it's even the presumed wisdom in places like this.
But the logic of hormesis and upregulatory effects dictates that space between doses be tested, in my opinion.
With sulforaphane, I realized a bad blood sugar drop on the second consecutive day of dosing.
My perception of it is that there is a definite lag in therapeutic effect response that warrants skipping days.
Using a 2-3 day intermittent dose frequency, I notice a different and better response on day two. When I haven't taken it.
On the day on which I take it, I feel more fragile (ie: migraine prone) and run down. By the second half of the second day, I feel good. That nights sleep can be great.
I'm still experimenting with it, but the message is to test.
But no, I don't think that it is logical to dose once per week with 7x of the daily dose. Take a normal daily dose. It isn't vitamin D.
Edited by Ames, 22 January 2022 - 04:00 AM.