AFAIK it's quite safe, they even give it to little baby's to induce sleep. People on amphetamines use it long-term for sleep and it works without any adverse effects.
The first Indian Clonidine batch I had was the real deal, just like where it was meant to be made for it lowered my blood-pressure that I felt ill/weak a bit (my blood pressure was indeed too low when measuring) but it also gave me good night time rest once on 0.4-0.7mg, I still woke up frequently but fell right back to sleep and the effects of lowered blood-pressure went away after a week or so when my body adjusted and because of the short half-life and because I was taking it only when going to sleep. People that take it for high blood-pressure need to take it 3-4 times a day. Though I've read somewhere tolerance can occur.
The second and third Indian batch from the same pharmacy was a whole different brand and it didn't do anything at all. I'm not planning to order there anymore even though they can send me the brand I want because every time I order with them they try to use my VISA card for fraud purchases. (Stupid fucks, I've told them several time my VISA card is prepaid so they don't even have to bother trying to leak it for fraud but they probably are too retarded to comprehend what prepaid means).
I'm fine with whatever it is unless it's addictive or has a long half-life (those drugs normally would make a person drowsy during the day thus the body adjusts to them in a short period of time) or has a risk of permanent side effects, a bit hesitant to take those. I gave Trazadone a go, unfortunately it makes my nose congested each time I take it, but yet to try Mitrazapine which is in my notes. Other potentially useful AD's: Amitriptyline, Mianserine (helpful, keep it as a backup), Trimipramine, Dothiepin, Agomelatine.
I've got the same problem, I hate it when a "sleep" drug has a long half-life and if it especially not meant to be made for sleep then you might get stuck up with effects and side-effects you can't tolerate.
Mirtazapine is a very good and clean drug imho. Apart from the severe drowsiness and weight gain at the beginning, which in theory, should level out once your body is adjusted to it (if it's like for example like Olanzapine where you keep gaining and gaining weight over a long period of time I won't recommend staying on it).
It's not available on the market but in clinics/psychwards in the Netherlands they use a liquid form that has as low as 3ml/6ml (if I remember correctly it's equivalent to 3mg/6mg according to my psychiatrist) of Mirtazapine to help people sleep.
My sister had a sort of a burn-out 5-6 years ago and 7.5mg Mirtazapine knocked her out until her sleep pattern normalizes. Even though she is not sick at all anymore and works fulltime she still takes the half of a 7.5mg as a maintenance dosage for sleep without having any negative effects or side-effects (apart from the weight gain she had at the beginning when she was put on it).
I however needed 15/30mg in order to have the sleep effect, on 45mg it rather worked stimulating. The dosage is something you should keep in mind, with most people the lower the dosage Mirtazapine, the better it'll help with insomnia and the smaller chance of having effects you do not want (apart from the big possibility of weight gain at the beginning, even at a low dosage).
Good that you mention Mianserine, I didn't even think of that one. It's like the sister drug of Mirtazapine, maybe, if I'm lucky, Mianserine won't interact with my Lurasidone and induce sleep. (noted)
Amitriptyline was one the dozens of drugs that seemed to work on me, however within a week I started having symptoms of tardive dyskinesia with my tongue. My tongue felt really really heavy and I barely couldn't speak normally, as days passed it became worse and it scared the shit out of me and I dropped it immediately. Though I don't think Ami was responsible for it but rather the combination of Lurasidone plus Amitriptyline.
Trimipramine, Dothiepin hmm never heard of those. (noted for research)
Agomelatine I've taken twice in my life, once it came on the EU market and once in this past period with sleeping issues. I have no idea what to think of it tbh. The first time I was on it for quite a while and when I look back at that period the antidepressant effects were neglectable weak. The second time (2 years ago or so) I asked for it as a potential sleep aid and it didn't do anything.
On a side-note when I take Melantonin as a sleep aid, it doesn't make me sleepy and/or drowsy, I just sleep shit like always and the next day I wake up rather stimulated/talkative but at the same time my head feels weird (annoying buzz kinda feeling) and my eyelids feel really heavy and it lasts all day.
She should've asked for some specific brands, like 'Клофелин' (active ingr - Clonidine). Talking about Russian drugs, one person posted their anecdote that Afobazole is synergic with Temazepam. But, it's not well researched, not to mention interactions with other meds, so might be dangerous.
Thanks for typing it in Russian. I've send it to her.
It's been many many years ago that I searched info about Afobazole (back in the days when I had severe anxiety). I remember that I liked the reviews but I didn't have the money/balls to purchase it.
Not that I'm rich now, I'm still poor haha.. So I rather first look into options that are also available in the Netherlands and/or like Clonidine are also very cheap on the internet.