As an aside, I am very interested in the question how vaccination sometimes triggers ME/CFS. Whereas ME/CFS is nearly always triggered by certain viral infections (such as by coxsackievirus B or EBV), and ME/CFS patients are normally found to have chronically high IgG antibody levels to their triggering virus, in a small percentage of cases, ME/CFS can be triggered by a vaccination.
Most infectious disease doctors view chronically high IgG as just evidence of a past viral infection which is now dormant; but ME/CFS doctors view these persistent elevations in IgG as evidence for an ongoing intracellular viral infection in the tissues of ME/CFS patients. And many researchers believe that it is these ongoing intracellular tissue infections which may be the cause of ME/CFS.
Now intriguingly, even in cases of vaccination-triggered ME/CFS, these patients are still found to have persistently high IgG antibody levels to the usual ME/CFS viruses. Which suggests perhaps the vaccination has weakened some aspect of immunity, allowing a dormant virus to reactivate as an intracellular infection, thereby causing ME/CFS.
So this is one possible theory of why vaccination can sometimes trigger ME/CFS: because it weakens some aspect of immunity, that allows intracellular infections to appear.
But the question is, what aspect of immunity might that be?
This is what I would like to know, because it might explain a lot about ME/CFS. ME/CFS seems to appear when the body cannot control intracellular viral infections (which are different to regular viral infection which produce viral particles).
Edited by Hip, 10 January 2024 - 09:27 PM.