3083 replies to this topic

[aim1]

She should have kicked him the vagina.

[bladedmind]

EXPONENTIAL GROWTH (of ivermectin data.  100% positive)

 

 

"Dr." Chris Masterson is a Ph.D. in some unnamed discipline, an MBA, and sells courses on Peak Prosperity.   

[Dorian Grey]

Dr Martenson's PhD is in pathology, sub-specialty of Neurotoxicology.  He's been one of my favorite commenters on the pandemic.  Links to all his studies are in the "show more" below the video.  Do they check out OK?

[Heisok]

Thanks for general Ivermectin information.

 

Will need to research dosing and other ingredients in the various products. Medication contents for different mammals could be very different. Package inserts, and black box warnings will be read.

The liquid products with accurate dosing could be best.

 

A quick review for CYP450 effects and interactions needs to be done.. Interactions could be significant for medications like Rapamycin.

I would hate for somebody to inadvertently have problems.

Edited by Heisok, 04 December 2020 - 04:13 PM.

[Dorian Grey]

A good explanation on how IVM might be working.  You may have heard an in vitro study generated a lot of excitement early on, but on further investigation it was found the importin alpha and beta inhibition detailed would require toxic doses.  This video details possible alternate mechanisms based on theory or computer modeling (no actual in vitro / vivo studies).  

 

 

Can't help but think more than one of these effects must be in play, as ACE2 spike/docking binding & RdRP most helpful early, during viral replication phase & STAT3 & CD-147 would benefit later phases.  As IVM is showing benefit at all stages of disease, there must be multiple therapeutic mechanisms.  

Edited by Dorian Grey, 04 December 2020 - 04:39 PM.

[aim1]

Astonishing silence around IVM. Youtube isn't censoring, FDA isn't banning sales, nothing in the news.

With the holiday super-surge going on & a remarkable flow of positive data, I can't help but think this will bust wide open soon.

Will be interesting to see how it is handled. Perhaps now that Trump is on the ropes, any and all therapies will be embraced?

2020 is over, Trump is gone, and the crisis has passed. Praise the Lord, we're saved! Thanks Joe!

[aim1]

Apparently you know nothing about biden.
Let's talk h1n1 for starters. 60,000,000 infections when they decided to stop counting.
His top guy admits the did everything wrong.
And now the sharp mind of biden comes up with...wear a mask for 100 days.
Brilliant.

[Daniel Cooper]

Let's not get into the political weeds here.

[Gal220]

 

Astonishing silence around IVM. Youtube isn't censoring, FDA isn't banning sales, nothing in the news.

With the holiday super-surge going on & a remarkable flow of positive data, I can't help but think this will bust wide open soon.

Will be interesting to see how it is handled. Perhaps now that Trump is on the ropes, any and all therapies will be embraced?

2020 is over, Trump is gone, and the crisis has passed. Praise the Lord, we're saved! Thanks Joe!

 

 

Im a hard righty, but I think this is mostly ineptitude and corruption of the FDA and CDC.  Ivermectin should have been approved or dismissed one way or another back in May or June, it was being mentioned  in April and has a long history of use. 

 

Fauci all panicked about offering 1-2 grams of vitamin C advice (what warm blooded male wouldnt tell Jennifer Garner the truth), and we should have had dozens of little trials like that quercetin/bromelain combo from the Lancet preprint in regards to H2O2, hespirdin , honesuckle, rutin etc. We finally get some quercetin info 11 months in, its a total joke, the term medical science is clearly a misnomer.

 

How long has Chiropractic been around and still considered quackery yet every sports franchise has one on staff?

Lots of small studies by Dr.Budoff in regards to blood pressure with aged garlic and coq10, but completely ignored since no large study. 

 

If Dr.Zalenko is right about the 84% fewer hospitalizations with HCQ, zinc, and azm - it does appear we let people die over politics, not to mention the dozens of jobs and businesses lost if we had adopted this early on.  Certainly Remdesivir proves we will fast track a questionable medicine for money at the expense of peoples health.  Fauci should be locked up for that mess.

 

Just imagine if this was a real virus killing 1 in 3 people regardless of age. Who has any confidence in these agencies to get something done other than wash our hands.

Edited by Gal220, 04 December 2020 - 11:37 PM.

[bladedmind]

Dr Martenson's PhD is in pathology, sub-specialty of Neurotoxicology.  He's been one of my favorite commenters on the pandemic.  Links to all his studies are in the "show more" below the video.  Do they check out OK?

 

He does report findable studies.  Maybe he's OK.  Profile struck me wrong on superficial examination.   

[bladedmind]

Thanks for general Ivermectin information.

 

Will need to research dosing and other ingredients in the various products. Medication contents for different mammals could be very different. Package inserts, and black box warnings will be read.

The liquid products with accurate dosing could be best.

 

A quick review for CYP450 effects and interactions needs to be done.. Interactions could be significant for medications like Rapamycin.

I would hate for somebody to inadvertently have problems.

 

IVERMECTIN & CV-19 SAFETY REVIEW 

Biggest worry is compromised blood-brain barrier.  If taking Ivermectin, consider reading the link.  

 

Ivermectin also used for scabies, rosacea, and demodex blepharitis.  The latter causes dry eyes, ivermectin may have helped me, not sure. 

[bladedmind]

Chiapas is the only state in Mexico that distributes Ivermectin, and it started in July, 2020.  

 Chiapas1.jpeg   34.5KB   0 downloads

 

More about Chiapas.

In Mexico they are the state with the best result in:

- Cases per inhabitant (low)

- Deaths per inhabitant (low)

- Hospital occupancy (low)

- UCI availability (high)

- Positivity in tests (low)

- Excess deaths (low)

 Chiapas2.jpeg   53.97KB   0 downloads

 

https://twitter.com/...865012624650241

Edited by bladedmind, 05 December 2020 - 03:04 AM.

[Dorian Grey]

If you haven't had enough news on ivermectin lately...  Here's The FLCCC Alliance press conference from Houston, Texas

 

 

These are all front line doctors, actually treating COVID patients in the field.

Edited by Dorian Grey, 05 December 2020 - 03:39 AM.

[shp5]

https://www.medrxiv....1.16.20232397v1

RCT shows no significant effect of 200 000iu Vitamin D upon hospitalization on outcomes

Edited by shp5, 08 December 2020 - 06:33 AM.

[bladedmind]

NYT’s only mentions of Ivermectin for CV-19 in 2020:

1. A Russian influence operation
2. Incorrect claim that “health experts” condemn its use in Latin America
3. Elevating Fringe Theories, Ron Johnson Questions Virus Science

The Wisconsin Republican has transformed his Senate panel into a forum for amplifying dubious theories and questionable treatments pushed by President Trump….

 

The selections underscore the extent to which Mr. Johnson, a former plastics baron who has made little secret of his disdain for the Washington establishment, has eagerly echoed the most conspiracy-minded and anti-science impulses of Mr. Trump and waded headfirst into battles even the president’s usually reliable phalanx of congressional defenders have been unwilling to fight….

 

Two others promote the use of ivermectin, a drug often used to fight lice and pinworms, to treat coronavirus patients, despite the National Institutes of Health’s recommendation against its use outside clinical trials.

 

 

The tone of the supposed news article is venomous.  One of the saddest things in the last five years has been the New York Times’ news coverage becoming quite unreliable.  I was a petty journalist covering politics many years ago and slanted articles towards my own political opinions.  I later realized that was wrong.  I don’t have special access to the truth.  As a reporter, one should fairly present he said, she said, and let the reader decide. 

 

Same event, different source

https://trialsitenew...ental-affairs/ 

 

You don't have to be a grand conspiracy theorist to recognize that propagandists and lobbyists can put heavy thumbs on the scale in the formation of public opinion and policy.   

 

Hypothesis:  Watch for heavy influence being brought to bear on trialsitenews' more neutral coverage. 

[bladedmind]

P.S.  "Science" is not a set of decided truths.  Science is the relentless questioning of claims to truth.

[Daniel Cooper]

There is an awful lot of editorializing in what is supposed to be a straight up news article and not an opinion piece on their editorial page.

 

 

[bladedmind]

EXPONENTIAL GROWTH (of ivermectin data.  100% positive)

 

 

Masterson video on Ivermectin deleted by Youtube.  

[Gal220]

Masterson video on Ivermectin deleted by Youtube.  

 

Yes, heaven forbid someone take an FDA approved medicine with a long history of use and solid data for a week or two.  Outrageous...

 

If you have been following Masterjohn's articles on CoVid, you quickly find out he is overtly cautious about making any claims.

 

Its just the socialist paradigm... they know how to think and spend your money better than you, period.

 

Medcram addressed this a while back in relation to vitamin D. Start in at about 6:30 for the the meat of it.

 

 

Edited by Gal220, 09 December 2020 - 03:09 AM.

[Dorian Grey]

A tale of two Senate Hearings. 

 

The second Senate Hearing about Outpatient Treatment for COVID-19: Highlights here:

 

https://covexit.com/...-19-highlights/

 

Mainstream media report on the hearing here: 

 

https://www.yahoo.co...-233349756.html

 

White House vaccine rollout marred by confusion, false claims

 

Oh well...  We tried (again).  Looks like Resistance is Futile...  We will be vaccinated!  

[Dorian Grey]

Masterson video on Ivermectin deleted by Youtube.  

 Martenson Responds!  

[jroseland]

A two notable Hydroxychloroquine alternatives: ARBIDOL® and RIBAVIRIN

 

 

Should you take pharmaceuticals to treat or prevent flu or the Coronavirus? What about vaccines?

An overview of ARBIDOL®, an Anti-influenza and anti-SARS drug along with RIBAVIRIN, a broad-spectrum anti-viral.

 

I have not taken these, I hope not to have to, as I’ve been implementing a bunch of natural nutraceutical herbal immunity biohacks, I haven’t gotten sick during the chilly Eastern European winter and neither has my wife who is doing all the same things as me. But, I like to have some pharmaceuticals like these on hand as a last resort in case me or someone close to me were really struggling with the flu or COVID-19.

 

Watch: Chloroquine Alternatives - Analysis of Pharmaceutical Anti-Virals vs Vaccines for Coronavirus

 

 

 

[Dorian Grey]

Ivermectin now back in stock at United Pharmacies 

 

https://www.unitedph...ivermectin.html

 

I used bitcoin, but don't know if there is alternate payment method.  

[Dorian Grey]

News Flash: Rudy Giuliani thanks Dr Zev Zelenko (and others) for his "miraculous" recovery.

 

https://twitter.com/...016426931101701

 

Wonder what Dr Z was prescribing?  

Edited by Dorian Grey, 11 December 2020 - 05:09 AM.

[bladedmind]

Literature review and hypothesis that photobiomodulation (e.g., LLLT) is a useful treatment for CV-19 lung inflammation. 

 

this review study was conducted to evaluate the direct effect of PBM on the acute lung inflammation or ARDS and also accelerating the regeneration of the damaged tissues. The indirect effects of PBM on modulation of the immune system, increasing the blood flow and oxygenation in other tissues were also considered….Results Seventeen related papers were included in this review. All of them were in animal models. They showed that the PBM could significantly decrease the pulmonary edema, neutrophil influx, and generation of pro-inflammatory cytokines (tumor necrosis factor-α (TNF-α), interleukin 1 beta (IL-1β), interleukin 6 (IL-6), intracellular adhesion molecule (ICAM), reactive oxygen species (ROS), isoform of nitric oxide synthase (iNOS), and macrophage inflammatory protein 2 (MIP-2)). Conclusion Our findings revealed that the PBM could be helpful in reducing the lung inflammation and promoting the regeneration of the damaged tissue. PBM can increase the oxygenation indirectly in order to rehabilitate the affected organs. Thus, the infra-red lasers or light-emitting diodes (LEDs) are recommended in this regard.

 

 

 

[bladedmind]

GREEN & BLACK TEA, ANDROGRAPHIS, CARRAGEENAN NASAL SPRAY

 

Green tea and better black tea wipe out coronavirus in vitro:

https://www.biorxiv.....12.04.412098v1

 

Significant inactivation of SARS-CoV-2 by a green tea catechin, a catechin-derivative and galloylated theaflavins in vitro

Potential effects of teas and their constituents on SARS-CoV-2 infection were studied in vitro. Infectivity of SARS-CoV-2 was significantly reduced by a treatment with green tea, roasted green tea or oolong tea. Most remarkably, exposure to black tea for 1 min decreased virus titer to an undetectable level (less than 1/1,000 of untreated control). An addition of (-) epigallocatechin gallate (EGCG) significantly inactivated SARS-CoV-2, while theasinensin A (TSA) and galloylated theaflavins including theaflavin 3, 3’-di-gallate (TFDG) had more remarkable anti-viral activities. Virus treated with TSA at 500 μM or TFDG at 100 μM showed less than 1/10,000 infectivity compared with untreated virus. TSA and TFDG significantly inhibited interaction between recombinant ACE2 and RGD of S protein. These results strongly suggest that EGCG, and more remarkably TSA and galloylated theaflavins, inactivate the novel coronavirus.

 

 

 

Andrographis in vitro

https://www.biorxiv.....12.08.415836v1

 

Anti-SARS-CoV-2 activity of Andrographis paniculata extract and its major component Andrographolide in human lung epithelial cells and cytotoxicity evaluation in major organ cell representatives

The coronavirus disease 2019 (COVID-19) caused by a novel coronavirus (SARS-CoV-2) has become a major health problem affecting more than fifty million cases with over one million deaths globally. The effective antivirals are still lacking. Here, we optimized a high-content imaging platform and the plaque assay for viral output study using the legitimate model of human lung epithelial cells, Calu-3, to determine anti-SARS-CoV-2 activity of Andrographis paniculata extract and its major component andrographolide. SARS-CoV-2 at 25TCID50 was able to reach the maximal infectivity of 95% in Calu-3 cells. Post-infection treatment of A. paniculata and andrographolide in SARS-CoV-2 infected Calu-3 cells significantly inhibited the production of infectious virions with the IC50 of 0.036 μg/mL and 0.034 μM, respectively, as determined by plaque assay. The cytotoxicity profile developed over the cell line representatives of major organs, including liver (HepG2 and imHC), kidney (HK-2), intestine (Caco-2), lung (Calu-3), and brain (SH-SY5Y), showed the CC50 of >100 μg/mL for A. paniculata extract and 13.2-81.5 μM for andrographolide, respectively, corresponding to the selectivity index over 380. In conclusion, this study provided experimental evidence in favor of A. paniculata and andrographolide for further development as a monotherapy or in combination with other effective drugs against SARS-CoV-2 infection.

 

 

 

 

New.  Carrageenan nasal spray may double the rate of recovery from coronavirus and influenza virus infections: re-analysis of randomized trial data

https://www.research...ticle/rs-108775

The cold coronavirus is not the same as the “novel coronavirus” we face today. 

 

Nasal carrageenan increased the recovery rate from all colds by 54% (95% CI 15% to 105%; P = 0.003). The increase in recovery rate was 140% in coronavirus infections, 119% in influenza A infections, and 70% in rhinovirus infections….Carrageenan had no meaningful effect on shorter colds. In the placebo group, 21 patients had colds that lasted over 20 days, compared with 6 patients in the carrageenan group. This corresponds to a 71% (P = 0.003) reduction in the risk of longer colds. Finally, in the placebo group, 37 patients had recurring cold symptoms after first being cured, compared with 16 in the carrageenan group. This corresponds to a 56% (P = 0.002) reduction in the risk of recurring symptoms. Given that carrageenan has an effect on diverse virus groups, and its demonstrated effects on two old coronaviruses, it seems plausible that nasal carrageenan may also have an effect on the new coronavirus SARS-CoV-2. Further research on nasal iota-carrageenan is warranted.

 

 

“Betadine” nasal carrageenan spray on Ebay or do it yourself:  https://biotheorist.....12-percent.pdf

 

 

Edited by bladedmind, 11 December 2020 - 06:32 AM.

[bladedmind]

EARLY OUTPATIENT TREATMENT UPDATE

 

The FDA has authorized for emergency use certain monoclonal antibodies for early outpatient treatment.  In case you missed it, it’s more in the investment and finance news than in the health news.   

https://www.cdc.gov/...re-illness.html

 

There “are insufficient data to recommend either for or against” their use.  They are only for people at high risk of disease progression.  A single intravenous dose of either Bamlanivimab (yes, Bam-ba-lam, everyone thinks of Black Betty) or casirivimab plus imdevimab.  Only permitted before hospitalization, not after. 

 

According to FDA, they’re doing a terrific job on approving treatments! 

https://www.fda.gov/...atment-covid-19

 

As illustrated by today’s action, the FDA remains committed to expediting the development and availability of potential COVID-19 treatments and providing sick patients timely access to new therapies where appropriate, while at the same time supporting research to further evaluate whether they are safe and effective,” said FDA Commissioner Stephen M. Hahn, M.D. “Through our Coronavirus Treatment Acceleration Program, the FDA continues to work around the clock and use every tool at our disposal toward these efforts.”

 

 

That’s it, no other therapeutics for CV-19, early or late, except for maybe late remdesivir, and dexamethasone but only for those on oxygen, and this official and bold FDA medical advice:  

Taking medications, like acetaminophen or ibuprofen, to reduce fever.

Drinking water or receiving intravenous fluids to stay hydrated.

Getting plenty of rest to help the body fight the virus.

 

Shoot, they won't even mention aspirin, which active clinicians and a few studies recommend as an early anticoagulant.  Must be too dangerous, or fringe science, or something.

 

I received on my IPhone today a mass text pushing an opt-in for Covid-19 exposure tracking.  I thought, why bother?  If I get symptoms I already know what to do:  take Tylenol, drink lots of water, and rest; if no longer able to breathe, write my will, and go to the hospital for supportive care.  

Edited by bladedmind, 11 December 2020 - 07:19 AM.

[albedo]

...

Wonder what Dr Z was prescribing?  

https://www.prnewswi...-301094237.html

[Mind]

GREEN & BLACK TEA, ANDROGRAPHIS, CARRAGEENAN NASAL SPRAY

 

Green tea and better black tea wipe out coronavirus in vitro:

https://www.biorxiv.....12.04.412098v1

 

 

Andrographis in vitro

https://www.biorxiv.....12.08.415836v1

 

 

 

New.  Carrageenan nasal spray may double the rate of recovery from coronavirus and influenza virus infections: re-analysis of randomized trial data

https://www.research...ticle/rs-108775

The cold coronavirus is not the same as the “novel coronavirus” we face today. 

 

 

“Betadine” nasal carrageenan spray on Ebay or do it yourself:  https://biotheorist.....12-percent.pdf

 

There was a trial of andrographis in humans in Thailand (I think, or maybe Vietnam) earlier this year. Does anyone know if that trial has concluded? Any data?

[Gal220]

https://www.prnewswi...-301094237.html

 

Tthe doctors link from the other page says he is also using Ivermectin