3083 replies to this topic

[adamh]

(Mind)

"Some people have postedabout this earlier in the thread."

 

That article was dated today so maybe it was something else you were thinking of?

 

I'm taking 200 mg of bht per day plus have a shipment of duovir on the way which is supposed to be effective against covid19. Here is a link about bht

 

https://www.ncbi.nlm.../pubmed/3021025

 

BHT, a common food additive and preservative, has been shown to be effective against many viruses. It attacks the lipid coating rendering the virus particle inactive. Lucky for us covid is a lipid virus. I have heard that its better to take it prophylacticly than to wait for symptoms. You don't want it to get a good grip on you so take a little every day then bump up to maybe a gram a day or more if definite symptoms come. It also helps prevent the common flu and some other illnesses.

 

My backup drug is this:

 

Duovir N (150+200+300)mg Tablet

Active Ingredients : Lamivudine, Nevirapine and Zidovudine

 

Those are all supposed to have some benefit against the virus. Hopefully I will not have to use it and will remain unscathed protected by bht. BHT has a long history of use, is gras according to the fda while those drugs most likely have side effects. But if the hospitals are full to overflowing and I get sick, I want something at hand. 

[lancebr]

Just saw an infectious disease control doctor on tv talking about this virus and he said that

based upon the information from patient cases that one of the biggest issues is even before

the patient knows that they have the virus the virus is doing damage to the lungs.

 

Depending on how much damage the virus has done to the lungs, before realizing symptoms

to know that you have the virus, is what can determine if it may be fatal or a situation where someone

is in the icu before recovery.

 

So what herbs or supplements have shown to possibly protect the lungs so once symptoms show

there has not been that much damage to the lungs?

[elc202]

can you put something in the humidifier or ultrasonic diffuser to clear or disinfect the air in your home?

some websites claim some essential oils have antiviral activity and they are good for flu season.

but if essential oils are useless, would it kill you if you put dettol in your humidifier?

[Adaptogen]

So what herbs or supplements have shown to possibly protect the lungs so once symptoms show
there has not been that much damage to the lungs?

Cordyceps is cheap, very safe, and has a large body of research supporting its efficacy for improving lung function, preventing airway remodeling and pulmonary fibrosis. Dosage in TCM is around 3 to 9 grams per day. Cordyceps militaris can be purchased on eBay for like $25/lb, and only needs hot water extracting (tea or using in cooking).

[niteinnyc]

Thoughts on a steroid inhaler to protect the lungs?

[Dorian Grey]

Just saw an infectious disease control doctor on tv talking about this virus and he said that

based upon the information from patient cases that one of the biggest issues is even before

the patient knows that they have the virus the virus is doing damage to the lungs.

 

Depending on how much damage the virus has done to the lungs, before realizing symptoms

to know that you have the virus, is what can determine if it may be fatal or a situation where someone

is in the icu before recovery.

 

So what herbs or supplements have shown to possibly protect the lungs so once symptoms show

there has not been that much damage to the lungs?

 

Premature infants are given "surfactant" to protect their lungs, which is comprised largely of phospholipids.  

 

https://breathe.ersj...content/9/6/476

 

"Phosphatidylcholine (PC) is the major phospholipid component of mammalian surfactant and is the primary constituent responsible for lowering surface tension in the alveoli."

 

Phosphatidylcholine?  That's simple Lecithin!  Quite safe and side effects next to nil. 

 

I take a highly refined polyunsaturated form of lecithin called PPC (polyenylphosphatidylcholine), brand name "PhosChol".  It appears (to me) to have many of the anti-inflammatory properties of fish oil, without the rancidity/oxidation issues associated with fish oil.  I've been taking low doses of this daily for over a decade now.  

 

http://www.phoschol.com/

 

Sold through Nutrasal: https://www.nutrasal...phos900-100.htm

 

This has been one of my top tier supps for many years.  Forever Young (like Dorian Gray)!  

Edited by Dorian Grey, 18 March 2020 - 05:57 AM.

[Dorian Grey]

Thoughts on a steroid inhaler to protect the lungs?

 

The French have been sounding the alarm about NSAID's & possible adverse events in COVID patients:  

 

https://www.yahoo.co...-160800002.html

 

Some are worried that steroidal anti-inflammatories might have a similar adverse effect.  Inflammatory response and immune response are closely related.  It may be steroidal meds have a place in halting a cytokine storm type situation, but timing would be essential with administering steroids to control this.  Early steroidal intervention might hamper immune response.  

 

First do no harm!  

[Dorian Grey]

can you put something in the humidifier or ultrasonic diffuser to clear or disinfect the air in your home?

some websites claim some essential oils have antiviral activity and they are good for flu season.

but if essential oils are useless, would it kill you if you put dettol in your humidifier?

 

If someone in your household has COVID, you're bound to get it too.  If the airborne virus doesn't infect you, the virus on surfaces will.  Running around disinfecting surfaces and adding chemicals to the air while living with an infected person would most likely be futile in my humble opinion.  

 

Best not to go overboard with disinfectants as they can irritate the airway and could predispose infection.  AVOIDING INFECTED PEOPLE is by far the best strategy.  Keep infected people out of your house and keep yourself inside.  If you must go out, this is where you're most likely to encounter the virus.  

 

Avoid pharmacies/chemist's as this is where infected people will go before they become acutely ill.  I'm going out for food, & little else.  I shop when stores are uncrowded (early morning or late at night).  

[niteinnyc]

Regeneron Pharmaceuticals on Tuesday morning announced a breakthrough in the search for a Covid-19 treatment. It has identified hundreds of virus-neutralizing antibodies that could potentially be used in a cocktail drug.

“Similar to the approach the company pursued for Mers and Ebola virus, we believe Regeneron’s Covid-19 antibody cocktail may offer efficacy in preventing and treating the virus,” SVB Leerink analyst Geoffrey Porges wrote in a note to investors.


A day earlier, Regeneron (ticker: REGN) said it had started trials with its existing arthritis drug, Kevzara, which might prove useful in treating lung inflammation in Covid-19 patients, keeping them off ventilators and out of intensive care units.


https://www.barrons....ent-51584468863

[kurdishfella]

Are kids immune to coronavirus? Scientists say children show surprising resistance to COVID-19--but could still be spreading it

https://thehill.com/...ve-largely-been

[lancebr]

I mentioned to a friend that I was going to purchase some BHT to take as a preventive measure

but they forwarded me the following study.

 

https://www.scienced...904208?via=ihub

 

So now if I am reading this right they say that BHT can damage the lungs.

 

.

[lancebr]

Premature infants are given "surfactant" to protect their lungs, which is comprised largely of phospholipids.  

 

https://breathe.ersj...content/9/6/476

 

"Phosphatidylcholine (PC) is the major phospholipid component of mammalian surfactant and is the primary constituent responsible for lowering surface tension in the alveoli."

 

Phosphatidylcholine?  That's simple Lecithin!  Quite safe and side effects next to nil. 

 

I take a highly refined polyunsaturated form of lecithin called PPC (polyenylphosphatidylcholine), brand name "PhosChol".  It appears (to me) to have many of the anti-inflammatory properties of fish oil, without the rancidity/oxidation issues associated with fish oil.  I've been taking low doses of this daily for over a decade now.  

 

http://www.phoschol.com/

 

Sold through Nutrasal: https://www.nutrasal...phos900-100.htm

 

This has been one of my top tier supps for many years.  Forever Young (like Dorian Gray)!  

 

So would the regular Phosphatidylcholine (PC) work just as good as the PCC? 

 

I actually have a bottle of the PC because I have a family member that had started showing

signs of dementia and bought a few bottles since that was recommended to try for memory issues.

 

When you say a daily low dose what amount is that?

 

Also, what is your take on this melatonin information that was posted earlier?  Would it be something you

would take and do you think it would be of use against this virus?

 

https://www.evolutam...7YhbQBwfLYhdykw

 

 

Thanks

 

 

Edited by lancebr, 18 March 2020 - 07:21 AM.

[kurdishfella]

so if you develop immunity to the first ''weak'' strain of coronavirus you still won't be 100% protected by the mutated versions of the coronavirus which are more aggressive but you will more easily be able to fight it off? so how many mutated versions have been found of this new  Sars-CoV2? like three so far?  S and L type and including the first one? the L type is 4% more stronger than S?

Edited by kurdishfella, 18 March 2020 - 09:13 AM.

[Izan]

 

Are kids immune to coronavirus? Scientists say children show surprising resistance to COVID-19--but could still be spreading it

https://thehill.com/...ve-largely-been

 

pretty breaking news from The Netherlands this morning.

 

Dutch scientists are now claiming that small amounts of the BCG vaccine (anti TB) transforms coronavirus from being aggressive to very mild. It triggers such an impressive immune respons that the coronavirus has a hard time attach itself to host cells, multiply and cause trouble there.

 

They are now injecting 1000 Dutch doctors and nurses working with coronavirus patients to see if they really are only getting mild symptoms.

 

Kids all over the world have been vaccinated with BCG vaccine plus their thymus glands are full intact?

 

 

https://nos.nl/nieuw...oronavirus.html

[lancebr]

pretty breaking news from The Netherlands this morning.

 

Dutch scientists are now claiming that small amounts of the BCG vaccine (anti TB) transforms coronavirus from being aggressive to very mild. It triggers such an impressive immune respons that the coronavirus has a hard time attach itself to host cells, multiply and cause trouble there.

 

They are now injecting 1000 Dutch doctors and nurses working with coronavirus patients to see if they really are only getting mild symptoms.

 

Kids all over the world have been vaccinated with BCG vaccine plus their thymus glands are full intact?

 

 

https://nos.nl/nieuw...oronavirus.html

 

The BCG vaccine is not used over here in the US for children.

 

So our children would not have that vaccine, but our children still seem immune to the virus.

[Izan]

Whoa!!

 

Relationship between the ABO Blood Group and the COVID-19 Susceptibility

 

 

Abstract

OBJECTIVE To investigate the relationship between the ABO blood group and the COVID-19 susceptibility. DESIGN The study was conducted by comparing the blood group distribution in 2,173 patients with COVID-19 confirmed by SARS-CoV-2 test from three hospitals in Wuhan and Shenzhen, China with that in normal people from the corresponding regions. Data were analyzed using one-way ANOVA and 2-tailed χ2 and a meta-analysis was performed by random effects models. SETTING Three tertiary hospitals in Wuhan and Shenzhen, China. PARTICIPANTS A total of 1,775 patients with COVID-19, including 206 dead cases, from Wuhan Jinyintan Hospital, Wuhan, China were recruited. Another 113 and 285 patients with COVID-19 were respectively recruited from Renmin Hospital of Wuhan University, Wuhan and Shenzhen Third People's Hospital, Shenzhen, China. MAIN OUTCOME MEASURES Detection of ABO blood groups, infection occurrence of SARS-CoV-2, and patient death RESULTS The ABO group in 3694 normal people in Wuhan showed a distribution of 32.16%, 24.90%, 9.10% and 33.84% for A, B, AB and O, respectively, versus the distribution of 37.75%, 26.42%, 10.03% and 25.80% for A, B, AB and O, respectively, in 1775 COVID-19 patients from Wuhan Jinyintan Hospital. The proportion of blood group A and O in COVID-19 patients were significantly higher and lower, respectively, than that in normal people (both P < 0.001). Similar ABO distribution pattern was observed in 398 patients from another two hospitals in Wuhan and Shenzhen. Meta-analyses on the pooled data showed that blood group A had a significantly higher risk for COVID-19 (odds ratio-OR, 1.20; 95% confidence interval-CI 1.02~1.43, P = 0.02) compared with non-A blood groups, whereas blood group O had a significantly lower risk for the infectious disease (OR, 0.67; 95% CI 0.60~0.75, P < 0.001) compared with non-O blood groups.In addition, the influence of age and gender on the ABO blood group distribution in patients with COVID-19 from two Wuhan hospitals (1,888 patients) were analyzed and found that age and gender do not have much effect on the distribution. CONCLUSION People with blood group A have a significantly higher risk for acquiring COVID-19 compared with non-A blood groups, whereas blood group O has a significantly lower risk for the infection compared with non-O blood groups.

 

 

https://www.medrxiv....78ozgjpNmkKLO34

French researches have also concluded this back in 2008 with regard to SARS.

 

And they even showed us the mechanism of action:

 

Inhibition of the interaction between the SARS-CoV Spike protein and its cellular receptor by anti-histo-blood group antibodies

 

Severe acute respiratory syndrome coronavirus (SARS-CoV) is a highly pathogenic emergent virus which replicates in cells that can express ABH histo-blood group antigens. The heavily glycosylated SARS-CoV spike (S) protein binds to angiotensin-converting enzyme 2 which serves as a cellular receptor. Epidemiological analysis of a hospital outbreak in Hong Kong revealed that blood group O was associated with a low risk of infection. In this study, we used a cellular model of adhesion to investigate whether natural antibodies of the ABO system could block the S protein and angiotensin-converting enzyme 2 interaction. To this aim, a C-terminally EGFP-tagged S protein was expressed in chinese hamster ovary cells cotransfected with an alpha1,2-fucosyltransferase and an A-transferase in order to coexpress the S glycoprotein ectodomain and the A antigen at the cell surface. We observed that the S protein/angiotensin-converting enzyme 2-dependent adhesion of these cells to an angiotensin-converting enzyme 2 expressing cell line was specifically inhibited by either a monoclonal or human natural anti-A antibodies, indicating that these antibodies may block the interaction between the virus and its receptor, thereby providing protection. In order to more fully appreciate the potential effect of the ABO polymorphism on the epidemiology of SARS, we built a mathematical model of the virus transmission dynamics that takes into account the protective effect of ABO natural antibodies. The model indicated that the ABO polymorphism could contribute to substantially reduce the virus transmission, affecting both the number of infected individuals and the kinetics of the epidemic.

 

 

 

https://www.research...roup_antibodies

[Izan]

The BCG vaccine is not used over here in the US for children.

 

So our children would not have that vaccine, but our children still seem immune to the virus.

I ended that sentence with a question mark, so I was just thinking out loud my friend.

 

But children DO have fully intact thymus glands and the thymus gland is quite a magical thing. It does not give 100 % protection against everything as you might already know, because children still get brain tumors, leukemia etc etc, but when it comes to recognizing, locating and annihilating pathogens, (bacteria, viruses etc) it's quite an effective weapon!

[Dorian Grey]

So would the regular Phosphatidylcholine (PC) work just as good as the PCC? 

 

I actually have a bottle of the PC because I have a family member that had started showing

signs of dementia and bought a few bottles since that was recommended to try for memory issues.

 

When you say a daily low dose what amount is that?

 

Also, what is your take on this melatonin information that was posted earlier?  Would it be something you

would take and do you think it would be of use against this virus?

 

https://www.evolutam...7YhbQBwfLYhdykw

 

 

Thanks

 

Haven't looked at the melatonin yet, but have a bottle around for my gal's insomnia. I'm willing to try anything that's safe if I get sick.  

 

The PC surfactant they give neonates is actually shot down directly into the lungs with a small catheter slid down their vent tube.  Don't know if PC taken orally might help, but choline is an essential nutrient and the body does use it to support cellular membranes.  If you're not eating well when ill, this might prevent deficiency at a critical time.  

 

The polyunsaturated fraction in PPC is supposed to have substantially more anti-inflammatory effect than simple PC.  It is sold as a "membrane therapeutic".  The alveolar membranes of the lung are inflamed with COVID, so theoretical potential with PPC in my book.  

[Izan]

French study, released today.

 

Treatment of hydrochloroquine PLUS azithromycin against Covid-19 gave a 100 % cure rate after only 6 days.

 

(N=20, though, but these are extraordinary times, people are dying by the hundreds each day)

 

https://drive.google..._IlWSHnGbj/view

 

 

 

 

 

 

 

 

 

 

 

[Dorian Grey]

Flu Vaccine Increases Coronavirus Risk 36% Says Military Study

 

https://www.disabled...knj7GMbJ3loYen0

 

https://www.ncbi.nlm...pubmed/31607599

 

Influenza vaccination and respiratory virus interference among Department of Defense personnel during the 2017-2018 influenza season

 

"Vaccine derived virus interference was significantly associated with coronavirus and human metapneumovirus"

 

This study coronavirus was NOT COVID, but apparently pre-COVID common cold coronavirus.  Still, something to think about.  

Edited by Dorian Grey, 18 March 2020 - 06:09 PM.

[thompson92]

Anyone have any decent in vivo data on 1) serum lactoferrin levels in adult humans given an oral supplement or 2) an IL-6 effect in any animal model with oral supplementation of lactoferrin with ideally some kind of flu-like viral infection.

 

I'm somewhat concerned about the required dose and effectiveness of Lactoferrin administered through oral means in this paper where influenza was given to a group of mice.  Per Shin, et al 

 

One possible reason behind the lack of effect of
orally administered LF and LPO on the virus yield regardless
of having antiviral activities in vitro is that these proteins were
not effectively absorbed from the intestine into circulation
and therefore did not exhibit direct antiviral effects in vivo in
the respiratory system. The serum levels of bovine LF and
LPO by ELISA determination were very low in the groups of
mice given these respective proteins on day 6 (mice given LF,
7.2 6.0 ng ml1; mice given LPO, 2.4 2.4 ng ml1),
whereas neither LF nor LPO was detectable in the control
mice (details not shown)

 

In which they noted the viral particle load wasn't found to be lower.  However, IL-6 was lower after 6 days (though higher after 4).

 

Viral particle load after infection with mouse given 62.5 mg of lactoferrin or lactoperoxidase:

 

https://imgur.com/a/KbdKuy4

 

 

IL-6 with same groups:

https://imgur.com/a/jCHHiIR

 

 

 

Shin K, e. (2020). Effects of orally administered bovine lactoferrin and lactoperoxidase on influenza virus infection in mice. - PubMed - NCBI . Ncbi.nlm.nih.gov. Retrieved 18 March 2020, from https://www.ncbi.nlm...pubmed/16014423

 

 

I see this group followed up by using an aerosol administration of lactoferrin/lactoperoxidase, and others have even used something like a vaginal administration to try to get it to the site of action and avoid being destroyed in the gut.

 

Thoughts?

Edited by thompson92, 18 March 2020 - 06:31 PM.

[kurdishfella]

Since plants produce caffeine and Salicylic acid (aspirin) to fight  intruders can they be used in high doses to fight off this virus?

Edited by kurdishfella, 18 March 2020 - 07:48 PM.

[adamh]

I mentioned to a friend that I was going to purchase some BHT to take as a preventive measure

but they forwarded me the following study.

 

https://www.scienced...904208?via=ihub

 

So now if I am reading this right they say that BHT can damage the lungs.

 

.

Anything taken in excess can hurt you or kill you. Hundreds of people die every year from aspirin overdose, thousands die from alcohol etc. The dose is the poison. They were testing those mice with huge doses

 

https://www.ncbi.nlm...ubmed/12396675/

 

"At acute doses of 0.5 to 1.0 g/kg, some renal and hepatic damage was seen in male rats."

 

Huge doses do seem harmful but the prophylactic dose I take is 200mg per day or maybe 12mg/kg - orders of magnitude less. Plus it does have a strong anti viral effect. So take your chances without or try a proven remedy. BHT is considered safe by the fda and allowed in food in reasonable amounts

 

http://www.delano.com/blog/?p=190

 

"200 to 400 milligrams of BHT ingested daily should be adequate to protect most people from infection by herpes and other lipid-coated viruses."

 

covid is a lipid coated virus. Its important to take it every day and not wait until you are sick. Nip it in the bud and you may never get sick from it.

[Dorian Grey]

The US will NOT be included in the WHO's trial of experimental treatments for coronavirus because it has not committed to the project (yet)

 

https://www.dailymai...treatments.html

 

No Remdesivir, Avigan, chloroquine for you!

[thompson92]

https://www.ebay.com...LY/254458306205

 

This guy has been selling truckloads of Chloroquine.  How do you all feel about 98.8% purity, below pharmaceutical grade?

[lancebr]

The US will NOT be included in the WHO's trial of experimental treatments for coronavirus because it has not committed to the project (yet)

 

https://www.dailymai...treatments.html

 

No Remdesivir, Avigan, chloroquine for you!

 

I guess it was a good thing to get a prescription filled for chloroquine.

 

I know of some people who have bought it from aquarium stores since it is used for fish.

 

Now working on one for hydrochloroquine since it has less side effects.

Edited by lancebr, 19 March 2020 - 12:30 AM.

[lancebr]

Some of these medical people need to get their act together when providing information.

 

Below is the information being put out by a nurse.

 

On the second one they are saying that US experts are saying ibuprofen is safe and not

to believe what France is reporting.

 

Then under how to treat they say to use cough suppressants.  I thought that was a bad

idea since you want to cough up the phlegm and not suppress your cough.

 

 

 

Olga Kagan, an RN in New York, offers these tips for treating yourself at home:

What you need

• Acetaminophen (Tylenol) in 325 mg tablets
• Ibuprofen (Advil) in 200 mg tablets (From KHOU: There are reports from France that they can aggravate coronavirus; US experts say that's not true and they are safe)
• Mucinex, Robitussin or DayQuil/NyQuil, whatever your cough medicine of choice is
• Tissues
• Humidifier: If you don’t have a humidifier, you can also just turn the shower on hot and sit in the bathroom breathing in the steam.).
• If you have a history of asthma and you have a prescription inhaler, make sure the one you have isn’t expired and refill it/get a new one if it is.

How to treat symptoms

• For a fever over 101, alternate Tylenol and Advil so you’re taking a dose of one or the other every 3 hours. (Again, check with your doctor before taking Advil.) 
• Use both cough suppressants and expectorants (most cough meds have both). 
• Drink a ton, hydrate hydrate.
• Rest lots.

[lancebr]

French study, released today.

 

Treatment of hydrochloroquine PLUS azithromycin against Covid-19 gave a 100 % cure rate after only 6 days.

 

(N=20, though, but these are extraordinary times, people are dying by the hundreds each day)

 

https://drive.google..._IlWSHnGbj/view

 

I dont know if it is the same study, but they just reported on the news that a study was

released today that was of 40 patients and designed very well scientifically and of those

40 patients all had a 100% cure rate using hydrochloroquine.

 

The doctor said that the FDA should give immediate clearance to use the drug for this

type of treatment.  They also said in the news that Trump is holding a special news conference

tomorrow with the FDA for some "exciting" news.

 

I am guessing it might be just for that topic.

 

 

.
 

[lancebr]

https://www.ebay.com...LY/254458306205

 

This guy has been selling truckloads of Chloroquine.  How do you all feel about 98.8% purity, below pharmaceutical grade?

 

I am trying to find the study I read last week about this, but if I remember right they found that chloroquine that

was not 100% purity and was lower purity was not as effective as the more pure stuff.

 

I mean if all you have on hand is the 98.8% then it is probably better then nothing.  I am trying to find that study

but I have read so many it is hard to keep up with everything.
 

[lancebr]

If we have to self medicate and have access to hydroxychloroquine then would doxycyline be a

good substitute for the azithromycin used in the study?

 

Azithromycin has more side effects including cardiovascular risks. And, both hydroxychloroquine

and chloroquine also have risks with the heart. 

 

This chart for treatment guideleins shows doxycyline as an alternative to azithromycin:

 

https://www.grepmed....munity-acquired

 

A study also found that doxycyline and azithromycin found no statistical difference for the treatment of

community acquired pneumonia outcomes:

 

"3788 patients met inclusion criteria: 3711 in the azithromycin group and 77 in the doxycycline group.

These were well-matched according to CAP severity and comorbidities. There was no statistical difference

in the composite outcome between the azithromycin and doxycycline groups (44.3% vs 51.9%, P = 0.18).

Multivariate analysis identified positive blood culture (OR 5.81, 95% CI 2.69–12.55), CURB-65 [2 vs 0]

(OR 1.24, 95% CI 1.05–1.47), CURB-65 [≥3 vs 0] (OR 2.4, 95% CI 1.22–4.71) and CCI (OR 1.1, 95% CI 1.06–1.14)

as risk factors for the composite outcome. Receipt of doxycycline was not associated with components of the composite

outcome in secondary analyses. Doxycycline was not associated with a statistical difference in the composite outcome

for non-ICU Veterans hospitalized for CAP compared with azithromycin. These data offer support for the inclusion

of doxycycline as an alternative regimen in current IDSA recommendations."

 

Another paper stated the following for patients over 65:

 

"Patients treated with macrolides may be at higher risk of developing CDI (Clostridium difficile). In addition, a large cohort

study reported an increase in cardiovascular deaths (which were most pronounced among patients with a high baseline

risk of cardiovascular disease) during azithromycin therapy. Given these premises, the risk-benefit analysis for treating

CAP may favor doxycycline, especially in patients over 65 years who would be receiving outpatient treatment.

 

It has also been found that doxycycline can lower IL-6 levels:

 

"In a randomized controlled trial of patients with dengue hemorrhagic fever, compared to patients who

received standard-of-care supportive treatment, those who also received doxycycline had significantly lower

mortality [20.9% vs 11.2% (p < 0.05)] and lower TNF and IL6 levels on days 3, 5, and 7"

 

 

So could we use doxycyline instead of azithromycin and still get the same results they did in the Covid19 study?

 

.

 

.

Edited by lancebr, 19 March 2020 - 02:37 AM.