My experience with Tyrosine is that it is very unpredictable, and there seems to be long-lasting tolerance, a million times more so than tolerance to say dexamphetamine or methylphenidate. I've gotten some very strong stimulating effects on rare occasions from just half a gram of tyrosine, and I could repeat it to an extent, if I took weeks off from it. As far as chronic use I don't know, I gave up on that pretty quickly.
It seems like not the best idea to try and just squeeze in dopamine everywhere. Even if you manage to you are altering so many different things without aim. Ofc tyrosine might be pretty harmless, I assume. If I were on the look for something to improve motivation without too much tension etc, then I'd probably look at the stuff that's already been used for that, all kinds of herbs and whatnot that probably have more specific mechanisms of action than to "increase dopamine levels in the brain". Or try and find some substance that has a more specific mechanism...
I read through a lot of that stuff long ago but I think he tries to cover too many things. I find it quite unlikely most of the stuff he mentions does all that much, as opposed to has some interesting pubmed articles related to some mechanism or other.
I don't use tyrosine chronically. My experience with it is that I can manage a continuous effect from it up to 3 days in a row, followed by a break of at least 4 or 5 days before taking it again. I combine it with cdp-choline for reasons I mention in this old post. And I usually only use during a few periods in a year, not on a continual basis.
Stimulation , which you mention, is actually not at all what Iike it for. In fact stimulation is something I tend to avoid as I have high anxiety levels. When it works, and when it's not being converted into a lot of norepinephrine/adrenaline, it usually gives me a nice calm focus and facilitates decision-making despite my high GAD, especially when associated with one of my various anti-anxiety arsenal tools. It's the best thing I found so far for this ( also my options are limited by the fact that methylphenidate and similar things are nearly impossible to get prescribed where I live, and highly illegal to import ).
It is only when it seems to be converting too much to norepiniehrine that it's effects become highly anxiety-triggering.
Anyway, so far the DBH inhibitors mentionned in the blog , SJW isn't a good idea for a variety of reasons ( it's effects on skin, retina, etc..), and california poppy ( eschscholzia ) has only one study mentioning potential for DBH inhibition, and in a pretty weak manner. Nevertheless I bought it since it is one of very few anxiolytic things I haven't tried so far, so even if doesn't help much with the tyrosine issue, maybe it may help a bit with my sleep/anxiety issues .
Edited by BlueCloud, 10 February 2020 - 06:39 PM.
