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5-HT1A - PSSD/ANHEDONIA From Ashwagandha

5-ht1a anhedonia ashwagandha st johns wort pssd

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#1 ErgogenicHealth

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Posted 02 February 2021 - 08:16 AM


What's up guys,

Lucas here.

I want to get a thread started on the 5-HT1A receptor.

Focusing in on the autoreceptor and the post synaptic receptor.

It appears that many of those suffering from PSSD are affected by any compound that targets this receptor.

Why does St. John's Wort REVERSE the negative effects of Ashwagandha? 

We know that St. John's Wort can upregulate 5-HT1A post synaptic receptor. 

What else can achieve this?

PSSD is destroying lives on the daily, the more we discuss this, the closer we will get to a cure. 


Please comment below if you can add any insights. 


  • unsure x 1

#2 Trazohell

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  • Location:Germany

Posted 07 March 2021 - 06:00 PM

We can't discussing something that nobody knows. People have done this for years without any breakthrough, and 5HT1A is just one from numerous old theories. 



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Also tagged with one or more of these keywords: 5-ht1a, anhedonia, ashwagandha, st johns wort, pssd

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