2 replies to this topic

[Michael Lustgarten]

NR and NMN are popular ways to try to boost levels of NAD+, but that approach hasn't worked every time in human studies. One reason for that may involve CD38, which degrades both NR and NMN. With the goal of boosting NAD+ levels during aging, why does CD38 increase with age, and what can be done about it?

[Mind]

Interesting connection with LPS and endotoxins. Thanks for sharing.

[Heisok]

There have been other threads discussing CD38 inhibition. Hopefully some more great information will also be shared in this thread.

 

Links to two of several:

 

https://www.longecit...ne/#entry847892

 

https://www.longecit...-consumer-cd38/

Edited by Heisok, 02 February 2021 - 10:01 PM.