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LPS Increases During Aging: Besides Calorie Restriction, What Else Can Reduce It?

Started by Michael Lustgarten , Feb 10 2021 12:07 PM
lipopolysaccharide lps aging alkaline phosphatase

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#1 Michael Lustgarten

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Posted 10 February 2021 - 12:07 PM


LPS increases during aging, which may explain the age-related increase for CD38 and decreased NAD+. LPS is decreased on a calorie restricted diet, but what else can reduce it? In this video, I present evidence for intestinal alkaline phosphatase's (IAP) role on LPS, and posit that interventions that increase IAP may be an important approach for increasing NAD+.

 

 


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