33 replies to this topic

[Michael Lustgarten]

I would caution anyone older increasing their rbc numbers. You run the risk of blood clots and all their horrible effects on health that we are all aware of.

That said, simply injecting a trt dose of 100mg testosterone will most definitely raise rbc levels so high you will need to donate at the red cross routinely.

Its your health and if want to risk the health risks which are very real, then its your body. Unless you have clinically low numbers and health effects of low rbc values, I would leave it alone. If you have a clinical issue then a doctor is in order.... But there seems to be a common thread on this forum of a mentality of avoiding doctors and treating ailments by eliminating sugar or taking megadoses of zinc and things like that.

 

I disagree. If you're older and RBCs have exhibited an age-related decline, and if you're using dietary means to increase them, which is lowest risk, it should improve health, not make it worse. I'd definitely caution against using drugs to increase them though, that's not what I'm suggesting. 

[albedo]

From last Bill Faloon's complete blood tests (as he posted in the Age Reversal Network mail list).

 

Again, I wonder about the intermittent fasting impact on the RBC and hemoglobin, both in the low of the reference range. I expected a bit this, as also in my case, though of course anecdotal and might also be due to existing pathology:

 

"...I also practice time-restricted eating so that I fast for 16-18 hours most days. I also practice time-restricted eating so that I fast for 16-18 hours most days. The pancytopenia that I’ve battled since before 2006 has normalized over the past year."

 

Faloon 3 2021.PNG

Faloon blood tests march 2021.pdf

 

Looks like despite all he is doing (and he is expert) RBC is not optimal for age. Am I wrong? His fasting? Mine is still declining 4.7 at 67, not obsessed but  ...
 

Edited by albedo, 13 January 2023 - 12:53 PM.

[Mind]

Looks like despite all he is doing (and he is expert) RBC is not optimal for age. Am I wrong? His fasting? Mine is still declining 4.7 at 67, not obsessed but  ...
 

 

Since intermittent fasting and calorie restriction are robustly proven to increase healthspan in almost every species, and to increase life extension in many model animals, there must be something we are missing with RBC levels and their correlation to aging.

[albedo]

Since intermittent fasting and calorie restriction are robustly proven to increase healthspan in almost every species, and to increase life extension in many model animals, there must be something we are missing with RBC levels and their correlation to aging.

 

I do not know Mind. Maybe. Could it be a sort of price to pay on one biomarker to have the overall beneficial effect you rightly point to e.g with fasting which I guess lowers your iron level and potentially vitamin B12 level if you tend to be vegetarian? Also, looking at the correlation with age in Michael's video, older people, both men and women, tend to eat less. It also turns out the geometrical size distribution of RBCs, as measured by the RDW (lower is better, as in Faloon's test) has the highest impact in Levine's Phenotypic Age algorithm (AFAICR there was a strong association of cardiovascular risk with higher RDW)

 RDW.jpg   61.39KB   0 downloads

doi: 10.18632/aging.101414