I have read a great deal on this site but found no explicit discussion of this topic that I think may be critical:
the need for interventions - in controlled, timed cycles.
It seems to me that the needed interventions in fending off or reversing aging involve things that may be contradictory.
There are things that trigger autophagy as cell repair
There are emerging treatments to kill off (not attempt repair) of senescent cells.
And there treatments to encourage stem cell replacement of cells removed or killed off.
If people are taking supplements for all three of these, I think it may be ineffective and self contradictory. Perhaps this accounts for why some interventions seem to work in some studies but not others. Perhaps it also
explains why reversing or stopping aging has been so difficult. The body follows many cycles or peak activities relative to circadian rhythm so this might only follow nature.
I greatly respect any regimen that reflects this sense of steps taken in cycles over time. Aside from Turnbuckle, I haven't found any but would appreciate hearing if there are.