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Possible to counteract dangers of anticholinergics with cholinergics?

diphenhydramine anticholinergic

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#1 Nootropic Cat

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Posted 01 October 2021 - 09:48 PM


Hi all,

 

I've recently become reliant on a combination of mirtazapine and diphenhydramine to sleep at night. I have really bad insomnia (a common symptom of chronic fatigue syndrome which I unfortunately have) and taking 30mg mirt + 50mg diphen is the only thing that seems to work. If I cut either dosage at all then then the insomnia reasserts itself.

 

I'm obviously concerned about the long-term dementia risk from taking an anticholinergic* chronically. I am however taking ALCAR and citicoline during the day, so I wonder: am I counteracting the potential damage?

 

*Are they both anticholinergic? I'm reading conflicting things about mirtazapine.


Edited by Nootropic Cat, 01 October 2021 - 10:04 PM.


#2 Nootropic Cat

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Posted 01 October 2021 - 10:17 PM

I see there's been one similar thread with one respondent: https://www.longecit...nergic-effects/

 

Other opinions much appreciated! :)



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Also tagged with one or more of these keywords: diphenhydramine, anticholinergic

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