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What to take with B6?

undermethylation homocysteine fatigue

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#1 Kris111

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Posted 23 November 2021 - 12:21 AM


Hello guys! Could you please help me with below question?

 

What other supplements/vitamins should I take alongside B6, that would be important co-factors, or helpful in proper utilization of B6? And what should I avoid?

 

I am planning to start taking B6 as a first step towards reducing elevated homocysteine levels. 

 

FYI in case if it matters - In addition to high homocysteine levels, I have undermethylation, high histamine, slightly high cholesterol, pure OCD, and tinnitus. 

 

(P.S. To Moderators: I originally posted this in Brain Health accidentally. I realized this is the right place. Apologies for posting again)


Edited by Kris111, 23 November 2021 - 12:25 AM.


#2 ironfistx

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Posted 24 November 2021 - 08:57 PM

How do you know you have elevated homocysteine?

 

How did you get tinnitus?  I have tinnitius from acoustic trauma.  Would you like me to share a list of what has worked?



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#3 drgs

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Posted 24 November 2021 - 09:02 PM

"What other supplements/vitamins should I take alongside B6, that would be important co-factors, or helpful in proper utilization of B6?"

 

More like other way around, B6 is helpful in utilization of nutrients



#4 Kris111

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Posted 24 November 2021 - 09:15 PM

How do you know you have elevated homocysteine?

 

I had my doc order a homocysteine test.  In April, it showed 23.5 umol/L.  The normal range is 3.7 - 13.9 umol/L

 


Edited by Kris111, 24 November 2021 - 09:15 PM.


#5 Kris111

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Posted 24 November 2021 - 09:23 PM

How did you get tinnitus?  I have tinnitius from acoustic trauma.  Would you like me to share a list of what has worked?

 

I don't know the cause of my tinnitus.  Have had it for almost 6 years. My guess, after going to dozens of doctors, naturopaths, all kinds of tests, etc., is that it is probably because of my teeth/jaw clenching during night and from anxiety.  According to one of the functional docs I went to, that may be ONLY one of many reasons.

 

Nothing has worked 100% otherwise I wouldn't have had it still.  But yeah a few things worked in anxiety and volume reduction, and there are a couple of things I have yet to try. What worked - getting good sleep, going out in nature - hiking/walks, stress reduction.  These things reduced the volume level. In terms of supplements, I have had no luck so far. Tried gingko and flavonoids. Maybe I haven't tried the right ones yet? The next thing I am going to try is get a dental guard.  I know I know. That should have been one of the first things to try. For the first 3 years or so, I really didn't know what caused it and even now it is just a guess.  But that is a logical next step for me. I am also looking at tinnitus holistically. I believe that if I work on my other issues (like homocysteine for example), it would also help.

 

You mentioned you got your tinnitus from acoustic trauma. Sorry to hear that. Guessing high volume speakers/headphones? What has worked for you so far? Any suggestions?



#6 Kris111

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Posted 24 November 2021 - 09:40 PM

"What other supplements/vitamins should I take alongside B6, that would be important co-factors, or helpful in proper utilization of B6?"

 

More like other way around, B6 is helpful in utilization of nutrients

 

So are you suggesting that taking B6 alone would be good enough? That would kinda be nice.  Because most B combination supps (like methyl guard, b-complex, etc) have an eggregious quantity of B12.  I already measure high in B12 beyond the normal range, and would like to avoid it if possible.



#7 ironfistx

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Posted 25 November 2021 - 02:55 AM

I don't know the cause of my tinnitus.  Have had it for almost 6 years. My guess, after going to dozens of doctors, naturopaths, all kinds of tests, etc., is that it is probably because of my teeth/jaw clenching during night and from anxiety.  According to one of the functional docs I went to, that may be ONLY one of many reasons.

 

Nothing has worked 100% otherwise I wouldn't have had it still.  But yeah a few things worked in anxiety and volume reduction, and there are a couple of things I have yet to try. What worked - getting good sleep, going out in nature - hiking/walks, stress reduction.  These things reduced the volume level. In terms of supplements, I have had no luck so far. Tried gingko and flavonoids. Maybe I haven't tried the right ones yet? The next thing I am going to try is get a dental guard.  I know I know. That should have been one of the first things to try. For the first 3 years or so, I really didn't know what caused it and even now it is just a guess.  But that is a logical next step for me. I am also looking at tinnitus holistically. I believe that if I work on my other issues (like homocysteine for example), it would also help.

 

You mentioned you got your tinnitus from acoustic trauma. Sorry to hear that. Guessing high volume speakers/headphones? What has worked for you so far? Any suggestions?

 

 

Yes, I've tried tons. Ok check it out, out of ALL the supplements that people say are useful, this is what helped me if I remember correctly.

  1. NR (this was probably 10 months after the noise that caused tinnitis)

  2. prince of peace ginseng and royal jelly vials. I swear these help. I've used ginseng by itself before and it did nothing, so maybe it's the royal jelly. I have to take 2 vials to feel anything, but it seems to lower the tinnitis. Could be placebo, but I wasn't expecting that. Let me be clear, the reduction seems to last. I just mean "to feel" anything like while I'm on it.

  3. Notch therapy. Save the money and do it yourself. I did this for a while and I'm not sure if it helped, but I think it might have.

  4. sleeping with earplugs. Everyone says this doesn't help. I swear mine improved when I began doing this.

  5. Wobenzym. I was taking this and noticed my tinnitis was not as loud anymore.

Right after I got tinnitis (right ear, noise cause), I started taking Lipoflavonoid. It's marketed strongly for tinnitis but I don't know that it does anything; a doctor told me about it. I'm not sure I would recommend it because I recall you can get the active ingredient elsewhere moreover it contains titanium dioxide. They were cool and refunded my money, however.

I additionally started taking Alcar and N-Acetyl-Cysteine. I read a study saying these, when taken before and after loud noises, prevents hearing damage. I don't know that they helped. I probably took them for a few months.

Here's the stuff I tried.

Vinpocetine

Ginkgo Biloba

Grape seed extract

Ashwaghanda (ksm-55)

PQQ

Various magnesiums

I tried some weird online audio programs too which I don't think did anything, excluding notch therapy, which I didn't do online because I did it myself. Oh, creatine is reported to be amazing for tinnitis. Seriously. I tried it, I don't remember if it helped.

 

Oh, some people say that listening to white noise upon an exposure to loud noise can lessen the tinnitis. You have to remember, I read all this stuff years ago and am trying to remember it. So for me, if I'm exposed to loud noise, I'll get a tinnitis flare 3 days later. When that happens, I'll immediately start taking Alcar and NAC and listening to white noise if I have it. I'll use ginseng royal jelly if I have any and CBD. What I mean is, I'll do this as soon as possible to the noise insult, NOT wait until the flare.

 

 

More on notch therapy
Part 1 - find the pitch of your tinnitus

Part 2 - make a white noise track and remove one octave of sound with your pitch as the center, luckily there is a plugin to do this on audacity

Part 3 - listen to the track

The filter is called a "notch" filter, hence the name notch therapy.

I forgot the explanation behind why it (is supposed to) works.


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#8 Kris111

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Posted 27 November 2021 - 07:39 PM

 

  1. NR (this was probably 10 months after the noise that caused tinnitis)

  2. prince of peace ginseng and royal jelly vials. I swear these help. I've used ginseng by itself before and it did nothing, so maybe it's the royal jelly. I have to take 2 vials to feel anything, but it seems to lower the tinnitis. Could be placebo, but I wasn't expecting that. Let me be clear, the reduction seems to last. I just mean "to feel" anything like while I'm on it.

  3. Notch therapy. Save the money and do it yourself. I did this for a while and I'm not sure if it helped, but I think it might have.

  4. sleeping with earplugs. Everyone says this doesn't help. I swear mine improved when I began doing this.

  5. Wobenzym. I was taking this and noticed my tinnitis was not as loud anymore.

 

Thank you for sharing. Seems like NR and Wobenzym are both helpful when tinnitus results from loud noise impact. Since mine is not from there, I wonder how much would it help me. Out of the two, wobenzym could be more promising. So I will try that. What brand and version of Wobenzym did you take?

 

What is your current tinnitus level on a scale of 1 to 10?

 

Out of the above 5, if you could do only one, which would you recommend the most?

 

 

More on notch therapy
Part 1 - find the pitch of your tinnitus

Part 2 - make a white noise track and remove one octave of sound with your pitch as the center, luckily there is a plugin to do this on audacity

Part 3 - listen to the track

The filter is called a "notch" filter, hence the name notch therapy.

I forgot the explanation behind why it (is supposed to) works.

 

 

Thank you. Would you mind if I message you one on one further about this?







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