69 replies to this topic

[johnhemming]

 

It would be interesting to know the number of diseases of ageing that are caused by the failure of stem cells to differentiate properly.

 

At the moment the list I have

Osteoporosis

Sarcopenia

atherosclerotic vulnerable plaque

 

Further to this I have done a video about the issue

 

and the previous one is relevant

 

[bentl]

A 2012 paper on K2

 

The Emerging Role of Vitamin K2

Manouchehr Saljoughian, PharmD, PhD

Department of Pharmacy,

Alta Bates Summit Medical Center,

Berkeley, California

 

US Pharm. 2012;37(1):HS-12-HS-14.  

 

https://www.uspharma...e-of-vitamin-k2

 

[Mind]

For those who do not know Patrick Thuet's story. I did a recent podcast with him. He gives an update on his rationale for supplementation and lifestyle hacks. He again describes in detail how one can reverse heart disease

[ironfistx]

For those who do not know Patrick Thuet's story. I did a recent podcast with him. He gives an update on his rationale for supplementation and lifestyle hacks. He again describes in detail how one can reverse heart disease

 

Wasn't aware this podcast existed.  Thanks.

[ekaitz]

For those who do not know Patrick Thuet's story. I did a recent podcast with him. He gives an update on his rationale for supplementation and lifestyle hacks. He again describes in detail how one can reverse heart disease

 

The thyroid marker he mentions to watch out, is free t3?

 

Also, is Ciprofloxacin the antibiotic he recommends to reduce k2 wasting bacteria in the gut?
 

Edited by ekaitz, 29 December 2024 - 11:13 PM.

[Mind]

The thyroid marker he mentions to watch out, is free t3?

 

Also, is Ciprofloxacin the antibiotic he recommends to reduce k2 wasting bacteria in the gut?
 

 

He suggests avoiding Cipro. I don't think he supplements with any antibiotic.

[smithx]

He suggests avoiding Cipro. I don't think he supplements with any antibiotic.

 

Cipro and all quinolones are extremely bad. They have a black box warning because they basically destroy your connective tissue. If you take cipro a few times your chance of rupturing a tendon increases dramatically, probably permanently. They are also associated with neurological adverse effects. Avoid.
 

https://pmc.ncbi.nlm...les/PMC4080593/

https://www.nature.c...598-021-93763-y

https://onlinelibrar...1555817817.ch27
https://pmc.ncbi.nlm...les/PMC7174713/

https://pmc.ncbi.nlm...les/PMC6036697/

https://pmc.ncbi.nlm...es/PMC10957204/

[Rocket]

I have a tooth that was borderline crown or root canal. They determined the crown was necessary and could avoid a root canal but the tooth has felt funny for years... Then when I went on super high dose k2, my tooth felt great. I def think k2 in high doses isv good for the teeth from my n=1

[Mind]

I did a "Part 2" interview with Patrick Thuet. Some interesting additional information about supplementation.

[pamojja]

"Part 2" interview with Patrick Thuet.

 

Just an addendum to this interview, where he said don't go above 45 mg/d of zinc, 200 mcg/d of selenium, and balance each 15 mg/d zinc with 1 mg/of copper - better than just follow such guidelines is to regularly check your blood with lab testing.

 

It took me 300 m/d of selenium for 10 year, to optimize Selenium dependent Glutathione peroxidase. Beside eating 2 Brazil nuts a day.

Even in average 52 mg/d zinc for that long, didn't normalize my deficiency of zinc blood levels.

And for me, it was a big mistake to try to balance zinc with only 1.3 mcg/d of copper. Copper shoot up too high. And even trying to avoid any copper since, still couldn't correct it years later.

 

It's too different biochemical individualities, not to test the blood with higher dose supplementation regularly.
 

Surprisingly, I found CoQ10 helps me with Stress induced chest pains. Above 150 mg/d of Ubiquinone, or 75 mg/d of Ubiquinol. That might not hold true for any others. Also, a recent study found Ubiquinone correlated with longevity, more than Ubiquinol.

 

K1 blood level was 5 times higher than upper end of normal, with only 2 mg/d after 3 years. Lab mistakes are of course also possible, so better to repeat regularly.

Edited by pamojja, Yesterday, 08:17 PM.