6 replies to this topic

[Michael Lustgarten]

https://www.youtube....h?v=dd_TXkHsKVI

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Edited by Mind, 05 July 2022 - 05:35 PM.

[Mind]

....in mice.

 

The edit was to fix the youtube link.

[Michael Lustgarten]

....in mice.

 

The edit was to fix the youtube link.

 

Ah, more specifically, it extends lifespan in yeast in flies, and is associated with increased lifespan in 2 mouse models of longevity (GHRH KO and CR). 

Whether it extends lifespan in mice is unknown, but I'm submitting a grant next week that will evaluate that!

[Daniel Cooper]

Seems like it has some good anti-cancer properties aside from whether it extends life in humans.

 

How would one increase the amount of Lithocholic Acid produced in the gut? Is there a bacteria particularly good at this? Can it be supplemented and is there a source?

[Michael Lustgarten]

Great questions. On the video-to do list is figuring out the answers...

[Harkijn]

See also this older thread:

 

https://www.longecit...ule-identified/

[Michael Lustgarten]

That data has been known since 2010, but yet there's so little press on lithocholate since then. In terms of how much is optimal, there's likely a U-shaped association, with too little and too much being bad for health and/or longevity.