2 replies to this topic

[ryukenden]

Hi

I like to buy Cysteamine which may reverse atherosclerosis as per some research.

 

I wonder if you know where to buy it.

 

Many thanks

[Daniel Cooper]

Could you link us to some of that research? I'd love to see it.

 

Thanks,

 

 

[FHC_guy]

Daniel, Here is a link that talks about cysteamine & it's positive effects on atherosclerosis:

 

https://studyfinds.o...-heart-attacks/

 

It is my understanding that cysteamine is a prescription drug that is not widely used. When I went to goodrx.com it states, "This is a limited distribution drug and is generally not available at a pharmacy.".

 

Wikipedia states that it's medical uses are as follows:

 

"Cysteamine is used to treat cystinosis. It is available by mouth (capsule and extended release capsule) and in eye drops.[14][7][8][5][9][6][10][15]

 

When applied topically it can scavenge free radicals[16] and lighten skin that's been darkened as a result of post-inflammatory hyperpigmentation, sun exposure and Melasma.[17][18][19][20] Tentative evidence suggests that it may be a more effective depigmentation agent than hydroquinone, retinoids and topical corticosteroids in individuals with chronic skin discoloration.[21][22][23] Topical application of cysteamine cream has also demonstrated similar efficacy to intradermal tranexamic acid injections for the treatment of Melasma but with much fewer adverse effects."

 

The good news is that there is an affordable nutraceutical that is probably metabolized into cysteamine. That nutraceutical is called pantethine. According the wikipedia: "In the second theory, pantethine is converted to two pantetheine molecules which are in turn metabolized to form two pantothenic acid and two cysteamine molecules. Cysteamine is theorized to bind to and thus inactivate sulfur-containing amino acids in liver enzymes involved in the production of cholesterol and triglycerides. What is known is that high doses of the related vitamin - pantothenic acid - has no effect on lipids.[2]"

 

Studies have shown that pantethine can improve lipids and reduce plaque. Perhaps it is the work of the cysteamine metabolite..

 

A does of 900 mg of pantethine supposedly can reduce ApoB by close to 30% after 4 months usage. When I first learned about this I took an ApoB test and then started taking 900 mg of Jarrow brand pantethine (450 mg x 2 daily). By adding pantethine to my stack and nothing else...my ApoB went from 107 to 81 (24.3% reduction) after 90 days. That was on top of the high dose statin I've been on for quite some time.

 

Below is a link to an invaluable article entitled, "The role of nutrition and nutritional supplements in the treatment of dyslipidemia" by Dr. Mark Houston. On page 11 of the .pdf it talks about Pantethine. Also note that on page 12 of .pdf that there is a typo: Box 12 should be entitled, " Increase reverse cholesterol transport.".

 

https://www.tandfonl....2217/clp.14.25

 

I hope this information can be of help to the both of you as well as anyone else interested in lipids & CAD prevention.

 

John