4 replies to this topic

[Michael Lustgarten]

https://www.youtube....h?v=k6Jqn_y1DV0

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[albedo]

Thank you Michael, interesting as habit with your posts!

I guess the eGFR is based on the creatinine 2021 formula right? There were changes last year. You might also consider in future cystatin-c and cystatin-c/creatinine estimators:

https://www.kidney.o.../gfr_calculator

I guess this does not change the content pf your post.

 egfr formulas.jpg   41.85KB   0 downloads

[Michael Lustgarten]

Thank you Michael, interesting as habit with your posts!

I guess the eGFR is based on the creatinine 2021 formula right? There were changes last year. You might also consider in future cystatin-c and cystatin-c/creatinine estimators:

https://www.kidney.o.../gfr_calculator

I guess this does not change the content pf your post.

egfr formulas.jpg

 

Thanks albedo. Cystatin C has merit as a biomarker of kidney function, as creatinine-derived eGFR can suffer from muscle-mass losses during aging (creatinine is proportional to muscle mass).

[albedo]

Thanks albedo. Cystatin C has merit as a biomarker of kidney function, as creatinine-derived eGFR can suffer from muscle-mass losses during aging (creatinine is proportional to muscle mass).

 

Absolutely!

In my case, while I succeed to keep the creatinine trending down (eGFR-creatine going up), the cystatin-c is trending up (eGFR-cystatin-c trending down) with age.

These are what they are: estimations and I guess a real creatinine clearance test should maybe be done.

When I combine all eGFR estimators I know about (7 different formulas) there is a trend of the average eGFR upward which is good.

[Michael Lustgarten]

Absolutely!

In my case, while I succeed to keep the creatinine trending down (eGFR-creatine going up), the cystatin-c is trending up (eGFR-cystatin-c trending down) with age.

These are what they are: estimations and I guess a real creatinine clearance test should maybe be done.

When I combine all eGFR estimators I know about (7 different formulas) there is a trend of the average eGFR upward which is good.

Without the creatinine clearance measurement, when kidney function declines, BUN and uric acid increase, as they're cleared less from the blood. To account for that, I also track those biomarkers.