If you're looking for perfection in science, I would suggest limiting your studies for consideration to those authored by Christ himself. The reason I like large metas is, any substantially biased author will have his bias diluted by the sheer size of the totality of data. To each his own.
I'm looking for a reasonable standard of accountability, not perfection. And based on a few hours research, I found multiple problems with the website.
I would not call this a "large meta" as much as a private curation. It upholds an overwhelmingly disproportionate number of positive result studies. It does not pool studies based on related methodology, protocol or time from infection. It lacks consistency and is at odds with other meta-analyses. It fails to differentiate (or even attempt to negatively weight) studies involving other therapeutics (vitamin D, zinc, azithromycin, etc). Overall it does not meet any of the requirements of a peer-reviewed meta-analysis and should not be used to draw conclusions.
Their website claims "It is invalid to use partial evidence from a small subset of studies and then claim there is not enough evidence", but ironically they appear guilty of the very charlatanism they seek to squelch.
What's unforgivable in my judgement is what Fauci did in 2020/21, when he essentially banned any doctor from trying anything to help the frightened seniors falling ill with the plague. I still remember jumping through the hoops to get HCQ & IVM from overseas pharmacies. I didn't know if they would work or not, but I wanted something to TRY. Anything at all would be better than sitting alone doing nothing as symptoms got worse. My idea of hell on earth! Give me a frickin' placebo for Christ's sake; but don't slam the door in my face.
Fauci just smiled, & said NOPE... No treatment for you till ya start turning blue... For TWO YEARS! Unacceptable!
Well then responsible science is unforgivable in your eyes. Experimental treatments do not become widely approved until safety and efficiency are demonstrated beyond a reasonable doubt, even if they are drugs which have a long history of use for other conditions.
Regrettably, the medical institution and governmental framework as we know it does not condone the experimental use of prescription only or controlled substances.
As far as "banning any doctor" from prescribing HCQ. It is simply not true. The FDA cautioned against the use of HCQ for COVID, and revoked its status under emergency use authorization. Doctors can, and have, chosen to prescribe it off-label. Some may have had their license suspended, but this likely represents the tip of the iceberg. Sometimes that's the price you pay for going against the grain and ethical standards of mainstream science. According to the Nuremberg code and the Helsinki declaration, human experimentation is not petmitted even during times of war, famine, or distress.
There technically were alternative methods of treatment available, you chose one which was regulated.
Edited by gamesguru, 17 June 2023 - 02:54 AM.