12 replies to this topic

[smithx]

https://onlinelibrar.../prca.202300048

[Dorian Grey]

I had to drive way out into the country, to a small town fire station to find the J&J jab in April 2021.  Got boosted, again with J&J in November.  Then, NEVERMORE!  

 

If for some reason I had to get another COVID jab, it certainly would be Novavax.  No mRNA lipid nano's for me!  

[smithx]

This is why I didn't post any description of the link in my message. To see if anyone reads anything here.

 

And yep, Dorian Grey failed the test. Lipid nanos are not even slightly related to the actual content.

[Mind]

I posted about this in the other vax thread too. It is serious.

 

Everyone who previously produced peer-reviewed studies about the MOA of the mRNA and how it was going into many organ systems, all of the serious side effects and deaths, were constantly labeled as unscientific conspiracy nuts (which is ironic considering the voluminous peer-reviewed evidence produced). Maybe now people will more seriously evaluate the mRNA injections instead of just doing what CNN and the CDC tells them to do.

[Dorian Grey]

This is why I didn't post any description of the link in my message. To see if anyone reads anything here.

 

And yep, Dorian Grey failed the test. Lipid nanos are not even slightly related to the actual content.

 

Read carefully mate.  

 

"If for some reason I had to get another COVID jab, it certainly would be Novavax.  No mRNA lipid nano's for me! "

 

It WOULD be Novavax, as I don't allow the mRNA lipid nanos in my bodkin.  Never had Pfizer or Moderna, and never will.  

Edited by Dorian Grey, 02 September 2023 - 03:13 PM.

[smithx]

Dorian Grey: the point of the paper is that the spike protein from the vaccines is still found in the body for up to 6 months. It has nothing to do with nanoparticles.

 

What I found interesting in the paper was the possible mechanisms.
 

1. It is possible that the mRNA may be integrated or re-transcribed in some cells.

2. It is possible that pseudo-uridines at a particular sequence position, as described in the article, induce the formation of a spike protein that is always constitutively active. But it seems very remote as a hypothesis.

3. It is possible that the mRNA-containing nanoparticle will be picked up by bacteria normally present at the basal level in the blood. In fact, the existence of blood microbiota in clinically healthy individuals was proven during the last 50 years. Indeed, indirect evidence
by radiometric analyses suggested the existence of living microbial forms in erythrocytes [25]. In addition, the observation of the PP- Spike marker in individuals vaccinated more than 30 days after the vaccine in about 50% of subjects could also be explained by the wide biodiversity of eukaryotic and prokaryotic microbiota identified in blood by next-generation sequencing technologies [25]

 

 

 

What I'm concerned about is potential integration of the mRNA with the DNA of some cells, utilizing reverse transcriptases from endogenous retroviruses, for which there is a little bit of evidence:
https://pubmed.ncbi....h.gov/35723296/
Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

 

[joesixpack]

Dorian Grey: the point of the paper is that the spike protein from the vaccines is still found in the body for up to 6 months. It has nothing to do with nanoparticles.

 

What I found interesting in the paper was the possible mechanisms.
 

 

 

What I'm concerned about is potential integration of the mRNA with the DNA of some cells, utilizing reverse transcriptases from endogenous retroviruses, for which there is a little bit of evidence:
https://pubmed.ncbi....h.gov/35723296/
Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

 

Thanks for this abstract. It says that "We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure."

 

Can anyone here explain what that means in terms of the health of a vaccinated person? It sounds bad for the liver.

[Dorian Grey]

Thanks for this abstract. It says that "We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure."

 

Can anyone here explain what that means in terms of the health of a vaccinated person? It sounds bad for the liver.

 

I read a deep dive into the mRNA vaccines back in March 2021, which turned me off them forever.  Liver damage from the cationic lipids is mentioned. 

 

https://www.longecit...-we-like/page-2

 

Submitted for your approval, around 3/4 way down the page.  PDF also attached, but it's a tall glass of water:

 

Interview with Dr. Vanessa Schmidt-Kruger / Hearing # 37 of German Corona Extra-Parliamentary Inquiry Committee 30 January, 2021

 

*VSK: I’m a cell biologist and my specialist field is the functional characterisation and elucidation of proteins, i.e., I understand how proteins are produced, how they are transported in the cell, how they are taken up by cells, how they are metabolised, how intra- and intercellular communication takes place, including within tissue, and how organs interact. This is all very important if one wishes to conduct a risk assessment: how the vaccine functions for example, and the dangers/risks of the lipid nanoparticles (LNPs). This technology is not really new: it’s novel as a vaccine, but we have been using these LNPs in research for over 20 years, and we have always been struggling with the problem of toxicity of the lipids and balancing this against their efficacy.

 

The first point is that the BioNTech vaccine that is currently already being used is not highly purified, it contains contaminants of certain components.  The problem that BioNTech had is that in the clinical phase the product, i.e. the RNA, was produced with completely different techniques to how it is being produced now. During the clinical phase they only needed small volumes of vaccine, they were able to use very expensive techniques that delivered highly purified end products. Now that they have entered mass production, that is no longer possible, they have had to switch to lower-cost processes.

 

t the RNA is transcribed from the DNA and then the DNA has to be eliminated, it is digested by enzymes: by DNAses. And if this DNA is not digested well enough, if residues are left, this harbours risks.  BioNTech has admitted that there are DNA contaminants.

 

It was found that the integrity of the RNA always varies in the batches that had been made.  So – the integrity of the RNA means of course the RNA quality. They have found that this is not very high: it was higher for the processes during the clinical phase.   they have found new batches with only 55% RNA integrity, i.e., half of it is basically unviable.  

 

VSK: To come back to Ms. Fischer’s question about the DNA. The problem is that when it contains DNA contaminants, then the situation is: well, with RNA it is relatively unlikely that it can integrate into the host’s cell nucleus. The situation is different with DNA, and especially in this case because you have contaminants of linearised DNA.  

 

the lipid nanoparticles get into all cells, not just the muscle cells – it is an error to believe the latter

 

So it is theoretically possible that this linearised DNA that is in there as a contaminant could integrate into the host’s cell nucleus in a dividing cell, linearised DNA is optimal for integration.

 

The vaccine itself, even if the DNA – that contamination – were not in it – is still a genetic intervention. 

 

there are further contaminants, there is double-stranded RNA for instance. The EMA Committee says it is slight, it is acceptable

 

There are also contaminants with regard to the lipids (30.32). There are two new lipids, they have focused on them. One is ALC-0315, that is the cationic lipid, and the other is ALC-0159, the PEGylated peptide, the PEG component. And they have found that the end product – that there are contaminants in the end product in some batches.

 

The technology of the nanoparticles. I don’t want to completely malign it. It’s a superb technology really. But the problem is that it is still much too early for use in human beings. The toxicity is still too high, that first needs to be eliminated, then it would really be a brilliant technology. There are many scientists working on getting rid of this toxicity, research has been conducted on that for years.

 

the LNPs consist of up to 50% of these cationic lipids: 50% is very high, they are toxic because they have this positive charge. This enables them to enter into interactions with other components of the cell really well, they can also basically interact with negatively charged amino acids. This destroys the proteins which lose their ability to function because they “unfold” as it is called. In principle they can interact with the DNA because the DNA is also negatively charged due to its phosphate groups, creating DNA strand breaks. They can also interact with other lipids because they are also negatively charged, especially the lipids of the cell membrane. E.g. the cell membrane of the mitochondria.  If however these cationic lipids gain entry, it is confirmed in many publications that they destroy this membrane, and this leads to the formation of a large number of oxygen radicals. These oxygen radicals create a lot of damage in the cell. They interact – they alter the amino acids, the cell pours out as many cytokines as it can, the oxygen radicals also attack membranes and create lipid peroxidation.  

 

The questions that arise before something like this comes onto the market are how long it remains in the body, divided up as follows: how long do the lipids remain, How long does the mRNA remain? How are they broken down? What is their distribution in the body?

 

So what is the distribution of the lipid nanoparticles (LNPs) in the animal trial?  They injected the whole muscle and watched how the lipids spread out throughout the body, and found that these lipids were in many organs after just 15 minutes.  They found evidence of the cationic lipid in the plasma for 12 days, and evidence of the PEG lipid for 6 days. So they remained for quite some time.  The cationic lipids are exclusively degraded in the cells, only 1% was found in the stool. This means the cells take the full hit of the toxicity.  One can still find 5% of the lipid in the liver after 4 - 6 weeks – that is incredibly long.  

 

cationic lipids have a half life of 20 to 30 days in human beings, and the elimination to 5%, so not really eliminated, takes 4 - 5 months.  That’s a long time.  

 

So why exactly is the liver being damaged? It’s because the liver is the organ that takes up the most lipoproteins. And why does it take up the most? Because one of its functions is to break down cholesterol; I’ve explained that the nanoparticles are bound to ApoE proteins. These make their way directly back to the liver where the cholesterol is broken down, and that’s why the liver comes into contact with a huge amount of this.  With the mice or rats, the damage disappears after 3 weeks: does some small damage remain in the liver, or does it regenerate completely? VSK: Yes, it regenerates completely. The liver is fairly robust.

Long-term studies and studies on possible autoimmune conditions were not conducted.

This mechanism crosses the blood-brain barrier due to the ApoE -mediated transport. So the LNPs can cause damage in the brain.  

RF: How long does one need to hold one’s breath when one has been vaccinated. A lifetime, or does there come a time when you can relax again? VSK: It depends on which damage you are observing. The lipids are there for 4 - 5 months. Damage can arise for as long as the lipids are there.  

Attached Files

•  RNAdangers.pdf   178.48KB   2 downloads

[Daniel Cooper]

 

What I'm concerned about is potential integration of the mRNA with the DNA of some cells, utilizing reverse transcriptases from endogenous retroviruses, for which there is a little bit of evidence:

https://pubmed.ncbi....h.gov/35723296/
Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

 

 

This is why the first deployment of an mRNA vaccine in the world should not have been giving it to a billion people after a very shortened investigational process.

 

We could never be sure that there were not any long term issues with the mRNA technology itself during such a short trial period and the downsides of finding a problem after you've given to over a billion people are rather serious.

 

I jumped into taking as well it so I'm in the group that did not think this through before acting.

[smithx]

Another reason:

The new Novavax vaccine (not sure if this was true of the previous one) has a full-length spike protein. The may provide a more diverse immunological response. '

 

[joesixpack]

I am not sure that more spike protein is a good thing. The spike protein seems to be causing all the problems.

[Heisok]

This is not to judge the appropriateness of getting any of the various vaccines; Simply information from Novavax's FAQ. They clearly state the occurrence of some of the side effects which some have been challenging.

 

"What are the risks of the vaccine?
There is a remote chance that the Novavax COVID-19 Vaccine, Adjuvanted could cause a severe allergic reaction. A severe allergic reaction would usually occur within a few minutes to one hour after getting a dose of the Novavax COVID-19 Vaccine, Adjuvanted. For this reason, your vaccination provider may ask you to stay at the place where you received your vaccine for monitoring after vaccination. Signs of a severe allergic reaction can include: 

• Difficulty breathing
• Swelling of your face and throat
• A fast heartbeat
• A bad rash all over your body
• Dizziness and weakness

Myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the lining outside the heart) have occurred in some people who have received the vaccine. In most of these people, symptoms began within 10 days following vaccination. The chance of having this occur is very low. You should seek medical attention right away if you have any of the following symptoms after receiving the vaccine:  

• Chest pain
• Shortness of breath
• Feeling of having a fast-beating, fluttering, or pounding heart

Side effects that have been reported in clinical trials with the Novavax COVID-19 Vaccine include:

• Myocarditis (inflammation of the heart muscle)
• Pericarditis (inflammation of the lining outside the heart)
• Injection site reactions: pain/tenderness, swelling, redness and itching
• General side effects: fatigue or generally feeling unwell, muscle pain, headache, joint pain, nausea, vomiting, fever, chills, decreased appetite
• Allergic reactions such as hives and swelling of the face
• Swollen lymph nodes

Side effects that have been reported in post-authorization use with the Novavax COVID-19 Vaccine include:

• Severe allergic reactions
• Myocarditis (inflammation of the heart muscle)
• Pericarditis (inflammation of the lining outside the heart)
• Paresthesia (unusual feeling in the skin, such as tingling or a crawling feeling)
• Hypoesthesia (decreased feeling or sensitivity, especially in the skin)

These may not be all the possible side effects of the Novavax COVID-19 Vaccine, Adjuvanted. Serious and unexpected side effects may occur. The Novavax COVID-19 Vaccine, Adjuvanted is still being studied in clinical trials."

 

Novavax also makes it very clear that this is not approved. It is only from an EUA

 

"Use of the Novavax COVID-19 Vaccine, Adjuvanted in the U.S.
The Novavax COVID-19 Vaccine, Adjuvanted vaccine has not been approved or licensed by the U.S. FDA, but has been authorized for emergency use by FDA, under an Emergency Use Authorization (EUA) to prevent Coronavirus Disease 2019 (COVID-19) as a primary series in individuals 12 years of age and older. The Novavax COVID-19 Vaccine, Adjuvanted vaccine is also authorized to provide a first booster dose at least 6 months after completion of primary vaccination with an authorized or approved COVID-19 vaccine to individuals 18 years of age and older for whom an FDA-authorized mRNA bivalent COVID-19 booster vaccine is not accessible or clinically appropriate, and to individuals 18 years of age and older who elect to receive the Novavax COVID-19 Vaccine, Adjuvanted because they would otherwise not receive a booster dose of a COVID-19 vaccine."

 

https://ir.novavax.c...-and-XBB-1-16-6

 

 

Edited by Heisok, 09 September 2023 - 06:49 PM.

[Empiricus]

If you do experience severe side effects from your pointless booster, good luck.  You will be on your own.

 

On the other hand, there are lots of treatment options for people who get COVID.