8 replies to this topic

[joesixpack]

Trying this as a new topic, it is a substance like Ivermectin, HCQ, Quinine Etc.

 

In my continuing search for "things that work", in case there are restraints put on the public, and what they can obtain in the future, I came across a supplement/substance - Artemisinin, which has anti-malarial, anti-viral and anti- cancer properties.

 

Has anyone had any experience with it? It is available as a supplement on Amazon.

 

https://draxe.com/health/artemisinin/

 

https://www.scienced...095809918305423

 

[Dorian Grey]

Interesting stuff...  Was looking at the wiki page, & it looks like generation of oxidative stress through iron liberation from hemoglobin is its primary mode of action.  

 

https://en.wikipedia...iki/Artemisinin

 

Mechanism of action:  As of 2018, the exact mechanism of action of artemisinins has not been fully elucidated.^[30] Artemisinin itself is a prodrug of the biologically active dihydroartemisinin. This metabolite undergoes cleavage of its endoperoxide ring inside the erythrocytes. As the drug molecules come in contact with the haem (associated with the hemoglobin of the red blood cells), the iron(II) oxide breaks the endoperoxide ring.^[31] This process produces free radicals that in turn damage susceptible proteins, resulting in the death of the parasite.^[32][33] In 2016 artemisinin was shown to bind to a large number of targets suggesting that it acts in a promiscuous manner. Artemisinin's endoperoxide moiety is however less sensitive to free iron(II) oxide, and therefore more active in the intraerythrocytic stages of P. falciparum.^[34] In contrast, clinical practice shows that unlike other antimalarials, artemisinin is active during all life cycle stages of the parasite

 

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I'm trying to figure how this might manifest with antiviral, or immune modulating properties, though I see how this might affect some forms of cancer.  

 

At my age, I'm stickin' with what I've got a track record with.  Both my COVID adventures were a walk in the park with HCQ (1st go-'round) and quinine (second dance).  I was worried if I got caught buying HCQ, I might get sent to Guantanamo, but quinine is a little less spooky.  

Edited by Dorian Grey, 06 June 2024 - 02:39 AM.

[joesixpack]

Thanks for your thoughtful input. 

 

After reading your posts, I added quinine to my supplies.

 

How about this supplement. It has massive doses of everything but the kitchen sink. https://www.amazon.c...,aps,216&sr=8-7

[Dorian Grey]

WOW, that's quite a kitchen sink combo bomb you've found there.  I don't see any red flags, though there are a couple of components I don't recognize. 

 

I tend to avoid the all in one combo pills myself, though that's just me.  There's usually one or more ingredients I'm not particularly enthusiastic about, or don't understand, and I like to thoroughly research everything in a supp before I take it.  I've also read about mixing & ratio issues of ingredients of different weights and textures.  How do they manage to get all the proportions exactly right in every capsule?  

 

I've actually pruned my stack of supps down as I've grown older.  I grasp simple concepts well, but prefer to avoid complexities in life.  Flattered you liked my logic on quinine!  Sometimes less is more!  

[Dorian Grey]

A couple of reasons I'm pruning my supp stack jumped out at me recently.  I had heard Taurine was supposed to be a fairly well documented elixir of longevity, & started taking this last year...  Now, all of a sudden, they are thinking it may be the reason for increased colon cancer in younger populations!

 

https://www.dailymai...ancer-link.html

 

Revealed: The popular drinks that contain taurine - after ingredient was linked to colon cancer in young people

 

Doh!  BLAST!  Into the trash with the taurine.  Colon cancer isn't something I want to fool around with.  

 

I was also on high dose Niacin for my recent heart/angina scare.  After taking this for a year, this pops up...  

 

"According to a February 2024 study published in Nature Medicine, high levels of niacin, also known as vitamin B3, may increase the risk of heart disease. The study found that two breakdown products of excess niacin, 2PY and 4PY, were linked to an increased risk of heart attack, stroke, and other adverse cardiac events. The study also found that 4PY can directly trigger inflammation in blood vessels, which can lead to atherosclerosis and damage over time."

 

What?  Oh CRAP!  OK, dumping the niacin!  

 

I'm trimming my stack to a few golden oldies, in order to avoid any more unpleasant surprises down the road.  

[joesixpack]

WOW, that's quite a kitchen sink combo bomb you've found there.  I don't see any red flags, though there are a couple of components I don't recognize. 

 

I tend to avoid the all in one combo pills myself, though that's just me.  There's usually one or more ingredients I'm not particularly enthusiastic about, or don't understand, and I like to thoroughly research everything in a supp before I take it.  I've also read about mixing & ratio issues of ingredients of different weights and textures.  How do they manage to get all the proportions exactly right in every capsule?  

 

I've actually pruned my stack of supps down as I've grown older.  I grasp simple concepts well, but prefer to avoid complexities in life.  Flattered you liked my logic on quinine!  Sometimes less is more!  

I agree, I came across this in my search for information on Artemisinin. It seems like overkill and I won't be using it. I am not a fan of mega dosing on anything.

[joesixpack]

A couple of reasons I'm pruning my supp stack jumped out at me recently.  I had heard Taurine was supposed to be a fairly well documented elixir of longevity, & started taking this last year...  Now, all of a sudden, they are thinking it may be the reason for increased colon cancer in younger populations!

 

https://www.dailymai...ancer-link.html

 

Revealed: The popular drinks that contain taurine - after ingredient was linked to colon cancer in young people

 

Doh!  BLAST!  Into the trash with the taurine.  Colon cancer isn't something I want to fool around with.  

 

I was also on high dose Niacin for my recent heart/angina scare.  After taking this for a year, this pops up...  

 

"According to a February 2024 study published in Nature Medicine, high levels of niacin, also known as vitamin B3, may increase the risk of heart disease. The study found that two breakdown products of excess niacin, 2PY and 4PY, were linked to an increased risk of heart attack, stroke, and other adverse cardiac events. The study also found that 4PY can directly trigger inflammation in blood vessels, which can lead to atherosclerosis and damage over time."

 

What?  Oh CRAP!  OK, dumping the niacin!  

 

I'm trimming my stack to a few golden oldies, in order to avoid any more unpleasant surprises down the road.  

Interesting information on Taurine.

 

I am a little concerned about the Niacin. I take NR, which is a form of niacin, or vitamin B3. I am going to have to look into that a little further.

[pamojja]

I took Artiemisinin together with HCQ against a malaria 20 years ago. It simply worked for that. That was even the last of in total 7 malarias in the course of 5 years, all treated differently.

 

I don't trust any no-name supplements on amazon. Use trustworthy companies for that.
 

Revealed: The popular drinks that contain taurine - after ingredient was linked to colon cancer in young people

 
Intuitively, energy drinks of course - along with the highly processed junk food it's usually taken - is of course a factor in colon cancer. The taurine therein alone much less likely.
 
 

I was also on high dose Niacin for my recent heart/angina scare.  After taking this for a year, this pops up...

 
Who would take the effort and take high dose niacin? Maybe especially those with already CVD manifested? - Not surprising at all.
 

 

 

 

 

 

 

 

 

 

 

 

 

Edited by pamojja, 06 June 2024 - 07:54 PM.

[joesixpack]

Thanks for the input, and information. 

 

I have seen posts from a few people on Longecity that have taken high doses of Niacin because it costs less that NR and they think it provides similar benefits.

Edited by joesixpack, 07 June 2024 - 12:54 AM.