Aging Biotech Info is a curated set of lists related to the aging-focused biotechnology field, maintained by one of the investors in the space and a coterie of helpful volunteers. The site started with companies and conferences, and has expanded from there. Maintaining lists in a rapidly moving field of research and commercial development is harder than it looks, and the effort is appreciated. The latest list to be added in a first pass form is an ambitious effort, as it aims to say something about the presently available therapies that are thought to slow or reverse aging, for some definition of "available", and some consensus on the evidence needed for a therapy to be thought to slow or reverse aging.
People tend to have opinions on this topic! If you want to start a debate among patient advocates for the treatment of aging, few approaches work as well as taking a position on which approaches to therapy are better or worse. At the same time, few people are hurrying to set up a roadmap for others to learn from. For other efforts to list and evaluate interventions, one might look at the Forever Healthy Foundation's Rejuvenation Now risk-benefit analyses, and the Lifespan.io Rejuvenation Roadmap. It takes a lot of work to assemble and keep up with this sort of mapping of the field, so if you appreciate what is being done here, consider volunteering a little of your time and knowledge to the organizers.
Announcing AgingBiotech.info/therapeutics, a table of available aging therapeutics
Here announcing agingbiotech.info/therapeutics (beta),a table of most available potential anti-aging therapeutics, including supplements, drugs, lifestyle interventions, etc. The goal isn't to judge or rank these therapies but to summarize other evaluations and link useful sources of information.
Important notes: I'm launching it not completely filled out on the assumption it's better to release the substantial info collected so far since many purported therapeutics are commonly discussed and used, but sometimes by people who haven't looked at much info. Many people experiment with the personal use of therapies despite the scientific understanding and evaluation of many being patchy. What data or analysis exists isn't easy to collect. There is no central place to find links to much of the relevant papers and data. This is meant to be one such collection.
The overall philosophy of Aging Biotech Info is that great things are on the way from aging biotech but not yet available. Some people naturally don't want to wait, but one should be cautious of over-interpreting available data for anti-aging therapies. This new table can aid deep dives. It is a jumping off point that is hopefully slightly better than just starting with a web search.
This is absolutely not a recommended "stack", nor a direct endorsement. My sense is that most molecules here don't yet come with enough evidence for most people to use them, especially at super-physiological levels, and the most important column is the who-needs-it column called "best diagnostics/biomarkers to determine individual need and to titrate dose", for which there are woefully inadequate answers for most things. I think that a lot of people overestimate how much good many supplement or drug molecules will do. Simultaneously my sense is that the lifestyle intervenations are woefully underestimated and underutilized, as well as being mostly safer.
I hope that this is useful to some people. Those who want to help fill in the missing details should reach out directly.
View the full article at FightAging
