11 replies to this topic

[smithx]

https://www.ncbi.nlm...es/PMC10974902/

 

 

 

Inactivated Poliovirus Vaccine Booster Reduces the Likelihood of COVID-19 Outcomes in Individuals Primed with Oral Poliovirus Vaccination

 

 

Introduction: Prior research explores whether seasonal and childhood vaccines mitigate the risk of SARS-CoV-2 infection. Although there are trials investigating COVID-19 infection in response to the effects of the oral poliovirus vaccine (OPV), there has been no prior research assessing COVID-19 outcomes in recently immunized adults with the inactivated poliovirus vaccine (IPV). Methods: SARS-CoV-2 infection and COVID-19 symptoms were analyzed across a cohort of 282 adults who received an IPV booster. Bivariate and multivariate regression models explored associations among variables related to vaccination histories and COVID-19 outcomes. Results: One year post-IPV inoculation, participants who had never received OPV were more likely to test positive for SARS-CoV-2 and experience COVID-19 symptoms, compared to those who had previously received OPV (OR = 3.92, 95%CI 2.22–7.03, p < 0.001; OR = 4.45, 95%CI 2.48–8.17, p < 0.001, respectively). Those who had never received OPV experienced COVID-19 symptoms for 6.17 days longer than participants who had previously received OPV (95%CI 3.68–8.67, p < 0.001). Multivariate regression modeling indicated COVID-19 vaccination did not impact SARS-CoV-2 infection or COVID-19 symptoms in this sample of adults who had recently received IPV. Discussion: Findings suggest IPV may boost mucosal immunity among OPV-primed individuals, and COVID-19 vaccination may not provide additional protection among those who had received IPV. Future, larger-scale studies should measure the extent of protective effects against COVID-19 to inform public health policies in resource-deficient settings.

 

 

Edited by smithx, 06 August 2024 - 02:35 AM.

[smithx]

Over the course of the year, Covid vaccine was 25% protective against infection, but IPV booster was 75% effective at preventing it.

[joesixpack]

Over the course of the year, Covid vaccine was 25% protective against infection, but IPV booster was 75% effective at preventing it.

Well, I did not see that coming.

[joesixpack]

Well, I did not see that coming.

Who remembers which vaccine they had when they were 5 or 6 years old? I am over 70. I think I might had both in different years. I remember getting it 3 or 4 times in grade school. They stopped giving the oral version in 2000, don't know why.

[smithx]

Who remembers which vaccine they had when they were 5 or 6 years old? I am over 70. I think I might had both in different years. I remember getting it 3 or 4 times in grade school. They stopped giving the oral version in 2000, don't know why.

 

It's no mystery. Before 2000 there was only OPV. So if you were born before 1995 or so, you definitely got the oral vaccine.

[Daniel Cooper]

I definitely remember getting the sugar cube with a pink liquid in it in the first grade. Apparently this would have been my third dose. I don't remember the other two.

[smithx]

I got the IPV vaccine yesterday at Walgreens. Just scheduled it online through their website, no questions asked, cost was $0 because insurance just covered it with no questions.

 

[smithx]

How many people here got the Polio vaccine based on the study I shared?

And if you decided not to, why not?

[joesixpack]

I will go first. After my experience with the Covid 19 vaccine and the circumstances surrounding it, I am very hesitant to take any vaccine, other than a tetanus shot. I will continue to watch this one to see if there are follow up studies.

[pamojja]

How many people here got the Polio vaccine based on the study I shared?

 

Last time had Polio vaccine, together with other necessary for overland travel though Africa, was in 1993 from a high rank medical officer. After swallowing the life-vaccine, he looked at me in disbelieve: Why the disgust? Well, it tasted very bitter, not sweet. "Sorry, accidentally gave you 10 times the dose!", after checking its label again. I was already on the bathroom to induce vomiting, while he still was on the phone with an international poison control center, and receiving instructions to do exactly just that.
 

 

And if you decided not to, why not?

 

10 times the dose at once was more than enough for me. No need to repeat such experiences with any other vaccine. It was my last in 1993. I didn't get Covid even once. My last sickness leave was 3 days in 2006. But before that, on my travels numerous tropical infections, for which there are no vaccines available.

 

 

 

 

 

 

 

 

 

 

[smithx]

pamojja you took the now-discontinued live oral polio vaccine. This is the current injection of inactivated virus.

[pamojja]

pamojja you took the now-discontinued live oral polio vaccine. This is the current injection of inactivated virus.

 

How many people here got the Polio vaccine based on the study I shared?

And if you decided not to, why not?

 

I knew it was the inactivated, which I didn't take. And one reason why I didn't.

 

Other reasons would be that I don't even remember the last serious respiratory viral infection. The last was 2006 with a 3 days only sickness leave.

 

Despite having all co-morbidities, except age at life expectancy. Against remissions of symptoms from co-morbidities, I successfully supplemented extensively for many years. Therefore, only rare supplements mentioned somewhat effective against covid, I not already took.

 

Edited by pamojja, 10 November 2024 - 10:15 AM.