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Ideal Lithium Dose for Longevity?

lithium

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#1 sub7

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Posted 16 October 2024 - 12:34 PM


In this latest podcast Matt Kaberlien discusses the potential link between lithium and longevity and the connection seems to be based on fairly solid data (though not yet absolutely conclusive)
 

 

However, it is super frustrating to see that absolutely no mention is made of what might be a possible dose. Any idea at all what kinf of ballpark we are talking about? would you experiment with 3-5 mr or 100 mg of lithium per day? 

 

Thanks


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#2 Mind

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Posted 16 October 2024 - 03:48 PM

I have used the life extension lithium product for a few years now. I started because of all the positive data, like you mentioned. This particular brand has 1000 mcg lithium orotate (once daily).


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#3 sub7

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Posted Yesterday, 03:31 PM

I have used the life extension lithium product for a few years now. I started because of all the positive data, like you mentioned. This particular brand has 1000 mcg lithium orotate (once daily).

 

Thanks a lot MIND

 

I am wondering if that dose is kept very low to err on the side of (extreme) caution, since Lithium is sometimes associated with kidney damage (of course this is likely at much much higher doses that are hundreds of times higher than the 1 mg you mention)

 

anyone else at all?


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#4 pamojja

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Posted Yesterday, 04:14 PM

anyone else at all?

 

I've got about 2.5 mg/d of Lithium, mainly from the high Mg mineral water Rogaska Donat Mg, in average for the last 16 years.

 

If you want a summary of science, of also unusual nutrients, usually Joe Cohen has it: https://selfhacked.c...rt_by=relevance

 

Tested my whole blood a couple of times for lithium. Normal range is 0.01 - 0.05 mg/l.

 

2012 - 0.05

2016 - 0,06

2018 - 0.11

2020 - 0.04

 

Optimal range is unknown. What I do know is that my higher than 'normal' levels at least didn't hinder my major remissions in 2017 (walking disability from PAD) and 2019 (PEMs from ME/CFS).

 

 

By the way, my kidney classified for chronic kidney disease stage 1 at least up to 2012. This year, my kidney markers had been best all those 16 years.

 

 

 


Edited by pamojja, Yesterday, 04:17 PM.

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#5 sub7

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Posted Yesterday, 10:34 PM

 

 

 

By the way, my kidney classified for chronic kidney disease stage 1 at least up to 2012. This year, my kidney markers had been best all those 16 years.

 

If I understand correctly, you have been taking lithium from 2008. And you said that until 2012 your kidneys were diagnosed as having stage 1 kidney disease. 

 

now since 2012 to today, your kidney health improved (ether despite of or due lithium) 

but how about between 2008 and 2012? Had your kidney health changed during that particular 4 year span, which I believe is your fisrt 4 years on lithium....

 

thanks a ton for sharing  



#6 pamojja

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Posted Yesterday, 10:58 PM

No diagnosis of CKD1 by an MD, but according to an online calculator, since the diagnosis of my main condition of PAD with walking disability16 years ago, until 2012 only. I have no kidney lab results from before 2008. Started with the mineral water with lithium in 2012 only. So absolutely no correlation to CKD, except the lack of lithium intake. Went up to 4.7 mg/d intake of Lithium from the water in the year 2017.

 

I've recorded all my intake of nutrients and lab result in spreadsheets, in such a long time there are large variations. Therefore, I only mentioned the average of the whole 16 years, even though - as in the case of lithium for the first 3 years - I didn't supplement.

 
 

 

 



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#7 pamojja

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Posted Yesterday, 11:10 PM

The CKD probably originated from the pain-treatment of a spondilodiscitis 24 years ago, where only up to 4.5 g/d of Ibuprofen alleviated the excruciating pain somewhat. Actually a suicidal dose of ibuprofen. But had no access to western medicine at that time. The good in the bad: All who I got to know later in life who experienced a spondilodiscitis with access to western medicine, got the spine mechanically fused and life-long morphine treatment against remaining pains. While for me, it was an 8-month episode only, with no requirement of painkillers afterward. Fused and healed by itself. But the kidney temporarily damaged thereby.







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