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Vorinostat - Anyone have any experience/know a source?

hdac anxiety vorinostat hpa depression groupbuy

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#1 JosephPC

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  • Location:United States

Posted 25 November 2024 - 05:27 AM


Hi all,

 

I have heard amazing things about the HDAC inhibitor Vorinostat (yes, the cancer medication) for anxiety and fear reconditioning even at low doses. With long lasting, permanent changes to the fear response without having to continually dose.

 

I have long suffered severe anxiety and, HPA axis dysfunction. After some mild success with sodium butyrate (a weaker HDAC inhibtor), I would really like to give this a shot. Does anyone have experience with this? 

 

Does anyone have a source, or know of any group buys?

 

Thank you!

 

Joseph



#2 johnhemming

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  • Location:Birmingham, UK

Posted 25 November 2024 - 04:10 PM

Sodium butyrate operates in the millimolar range and Vorinostat in the nanomolar range there are loads in the micromolar range.  I haven't done a class analysis, but there are loads such as curcumin, quercetin, pterostilbene etc.



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