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Boron (Boric Acid): Anti AGE, Gut Ribose production, etc?

boron age nad

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#1 Logic

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Posted 31 December 2024 - 03:38 PM


I'm way out of practice in this field of study so this is just some interesting points on Boron (and Boric Acids) that may be worth further research.

 
Boric acid: A simple molecule of physiologic, therapeutic and prebiotic significance
 
boric acid and borax supplementation on lipid peroxidation (LPO), antioxidant activity
and DNA damage in rats have been investigated. Boron supplementation (100 mg/kg) in diet was found to
decrease LPO, and enhance the antioxidant defense mechanism and vitamin status

A wide array of sugars, including ribose, can be formed from formaldehyde (formose reaction) under pos-
sible prebiotic conditions, however, ribose has no selectivity and is rather unstable [51] . Boric acid and borate
minerals have been suggested to play a crucial role in transforming the prebiotic organic molecules to give
ribose in a stable form
by acting as a complexing agent. It is well known that boric acid and borate complexes
with 1,2-diol and 2,3-diol compounds and the cyclic form of ribose presents two hydroxyl groups in a cis
configuration for complexation with boron. Benner and co-workers demonstrated that ribose formation from
formaldehyde and glycolaldehyde is stabilized in the presence of borate [52] . da Silva and co-workers showed
possible clues on the roles of borate ions, alkaline and earth alkaline ions in the synthesis and stabilization
of ribose during the pre-RNA period [53] .

https://www.research...ic_significance
 

Effects of boron-containing compounds on cardiovascular disease risk factors
 
BCCs may inhibit Maillard reactions, by forming stable borate esters with cis-diol on furanose rings, thus making possible the chemical evolution in aqueous media of sugar and aminoacids, simultaneously, at temperatures of 80–100 degrees C [127]. As a result, borate/borate ester anions in living systems may inhibit glycation.
 

BCCs (as borate) have been demonstrated to increase NAD+/NADH ratio in animals

https://www.scienced...946672X18301561
 


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#2 Galaxyshock

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Posted 22 January 2025 - 11:04 AM

Cool, I've had only the impression of Boron for testosterone boosting properties, but it seems to be effective of various things.

 

I get 3 mg of Boron from my multivitamin, but I think the optimal dosage may around 10 mg range.


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#3 ironfistx

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Posted 26 January 2025 - 09:48 PM

I'm curious about boron after reading the study that said places with <1mg boron per day have 20-70% arthritis and 3-10mg per day have 0-10%.

 

https://pubmed.ncbi....ih.gov/7889887/

 

I was taking Swanon boron (6mg) and felt fine.  When it ran out, I purchased NOW boron (3mg) and started having chest pain.  I discontinued and within a few weeks it went away.  The peculiar part is they were the same boron, bororganic glycine from Albion.



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#4 Logic

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Posted 01 February 2025 - 08:48 AM

I'm curious about boron after reading the study that said places with <1mg boron per day have 20-70% arthritis and 3-10mg per day have 0-10%.

 

https://pubmed.ncbi....ih.gov/7889887/

 

I was taking Swanon boron (6mg) and felt fine.  When it ran out, I purchased NOW boron (3mg) and started having chest pain.  I discontinued and within a few weeks it went away.  The peculiar part is they were the same boron, bororganic glycine from Albion.

 

If you look up:
Dr Ali Erdemir Argonne National Labs Boric Acid lubricant
There is a lot of info on BA doing wonders for friction and wear in mechanical bearings due to the lamellar crystalline shape of the molecules/crystals.  (I tested; it works amazingly)

As Boron + Water inevitably ends in BA; I think some of that research may well apply to biological 'bearings' too..?

I'd also say; as it very likely ends up as BA anyway?; BA is the cheapest way of taking Boron.


Edited by Logic, 01 February 2025 - 09:25 AM.






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