Dr. Stephen Spindler (University of California Riverside) presents preliminary information on compounds that mimic calorie restriction and result in increases in Lifespan in Mice. OAA (oxaloacetic acid, benaGene TM) was one of the leading compounds to increase lifespan. We shall continue to follow Dr. Spindler's work to see if his initial results continue. See his presentation on calorie restriction mimetics at the Manhattan Beach Project Longevity Conference in Miami in November 2009:
There are some other great videos you may want to watch as part of the conference also.
Good video. He mentions BenaGene early on but doesn't want to plug it again by company name at the end. :-) He states no one knows how it works but I see you have attempted to explain it to some degree here.
His warning about 'combinations' that starts @~6min in is just more confirmation of the complexity of using multiple drugs and supplements.