First, for my fellow laymen and women -- may I please present some introductory information regarding the primary source of evidence;
Archives of Dermatology -- a publication of the
American Medical Association?
Some information on the AMA from Answers.com, provided by US History Encyclopedia:
American Medical Association
American Medical Association (AMA) was founded on 7 May 1847 as a response to the growing demands for reforms in medical education and practice. Dr. Nathan S. Davis (1817–1904), a delegate from the New York State Medical Society who later came to be known as the "founding father of the AMA," convened a national conference of physicians to address reforms in medical education, medical ethics, and public health. On 7 May 1847 more than 250 physicians from more than forty medical societies and twenty-eight medical colleges assembled in the Great Hall of the Academy of Natural Sciences in Philadelphia and established the American Medical Association. A Committee on Medical Education was appointed, and minimum standards of medical education were established. The first national code of American medical ethics, the cornerstone of professional self-regulation, was adopted. Written by Dr. John Bell (1796–1872) and Dr. Isaac Hays (1796–1879) and published in 1847, the Code of Medical Ethics of the American Medical Association provided guidelines for the behavior of physicians with respect to patients, society, and other medical professionals.
Throughout the nineteenth century the AMA worked to expose fraudulent and unethical practitioners and to limit licensure to allopathic physicians. In 1883 the Journal of the American Medical Association (JAMA) was established with Nathan Davis as the first editor. By 1901, JAMA was reporting a circulation of 22,049 copies per week, the largest of all medical journals in the world.
Membership, however, remained small, including only 10,000 of the 100,000 orthodox physicians. In 1901 the AMA underwent a major reorganization to become a more effective national body by providing proportional representation among state medical societies. The House of Delegates was established as the legislative body of the AMA. Each state society was allowed a specific number of delegates with voting rights. By 1906, membership in the AMA exceeded 50,000 physicians, and educational and licensing reforms began to take hold.
The newly established Council on Medical Education inspected 160 medical schools (1906–1907), and in 1910 the Flexner Report, Medical Education in the United States and Canada, was published. Funded by the Carnegie Foundation and supported by the AMA, the report exposed the poor conditions of many schools and recommended implementing rigorous standards of medical training. By 1923 the AMA had adopted standards for medical specialty training, and in 1927 the association published a list of hospitals approved for residency training.
By World War I, the AMA had become a powerful political lobby. Wary of governmental control, it fought proposals for national health insurance. The 1935 Social Security Act passed without compulsory health insurance due to AMA influence. Physician membership grew steadily to over 100,000 physicians by 1936. The AMA continued to fight government involvement in health care with a campaign against President Truman's initiatives in 1948. In 1961 the American Medical Political Action Committee (AMPAC) was formed to represent physicians' and patients' interests in health care legislation.
The AMA continued to work on numerous public health initiatives, including declaring alcoholism to be an illness (1956), recommending nationwide polio vaccinations (1960), and adopting a report on the hazards of cigarette smoking (1964). AMA membership exceeded 200,000 physicians by 1965. From 1966 to 1973, the AMA coordinated the Volunteer Physicians in Vietnam program and in 1978 supported state legislation mandating use of seat belts for infants and children.
In 1983, membership included 250,000 physicians. As AIDS became an epidemic in the 1980s, the AMA passed a resolution opposing acts of discrimination against AIDS patients (1986) and established the office of HIV/AIDS (1988).
By 1990, health maintenance organizations (HMOs) and other third-party payers were involved extensively in health care delivery. Health care reform had become a political priority. In 1994 and 1995 the AMA drafted two Patient Protection Acts, and in 1998 the AMA supported the Patient's Bill of Rights.
In 2001, AMA membership included 300,000 physicians. As new threats to the nation's health, such as bioterrorism, began to emerge in the twenty-first century, the AMA continued to rely on the principles in the AMA Code of Medical Ethics (revised 2001) and the democratic process of the AMA House of Delegates to guide its actions and policies to fulfill its mission as "physicians dedicated to the health of America."
Bibliography
Baker, Robert B., et al. The American Medical Ethics Revolution: How the AMA's Code of Ethics Has Transformed Physicians' Relationships to Patients, Professionals, and Society. Baltimore: Johns Hopkins University Press, 1999.
Duffy, John. From Humors to Medical Science: A History of American Medicine. Chicago: University of Illinois Press, 1993.
Starr, Paul. The Social Transformation of American Medicine: The Rise of a Sovereign Profession and the Making of a Vast Industry. New York: Basic Books, 1982.
Stevens, Rosemary. American Medicine and the Public Interest: A History of Specialization. Berkeley, Calif.: University of California Press, 1998.
Now, here's some information I found August 10, 2007 at Wikipedia that seems to be accurate:
Archives of Dermatology
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Archives of Dermatology is a monthly professional medical journal published by the American Medical Association. Archives of Dermatology publishes original, peer-reviewed reports and discussions that address the effectiveness of diagnosis and treatment in medical and surgical dermatology, pediatric and geriatric dermatology, and oncologic and aesthetic dermatologic surgery.
Here is the study abstract that may be of interest:
Vol. 143 No. 5, May 2007
Study
Improvement of Naturally Aged Skin With Vitamin A (Retinol)
Reza Kafi, MD; Heh Shin R. Kwak, MD; Wendy E. Schumacher, BS; Soyun Cho, MD, PhD; Valerie N. Hanft, MD; Ted A. Hamilton, MS; Anya L. King, MS; Jacqueline D. Neal, BSE; James Varani, PhD; Gary J. Fisher, PhD; John J. Voorhees, MD, FRCP; Sewon Kang, MD
Arch Dermatol. 2007;143:606-612.
Objective To evaluate the effectiveness of topical retinol (vitamin A) in improving the clinical signs of naturally aged skin.
Design Randomized, double-blind, vehicle-controlled, left and right arm comparison study.
Setting Academic referral center.
Patients The study population comprised 36 elderly subjects (mean age, 87 years), residing in 2 senior citizen facilities.
Intervention Topical 0.4% retinol lotion or its vehicle was applied at each visit by study personnel to either the right or the left arm, up to 3 times a week for 24 weeks.
Main Outcome Measures Clinical assessment using a semiquantitative scale (0, none; 9, most severe) and biochemical measurements from skin biopsy specimens obtained from treated areas.
Results After 24 weeks, an intent-to-treat analysis using the last-observation-carried-forward method revealed that there were significant differences between retinol-treated and vehicle-treated skin for changes in fine wrinkling scores (–1.64 [95% CI, –2.06 to –1.22] vs –0.08 [95% CI, –0.17 to 0.01]; P<.001). As measured in a subgroup, retinol treatment significantly increased glycosaminoglycan expression (P = .02 [n = 6]) and procollagen I immunostaining (P = .049 [n = 4]) compared with vehicle.
Conclusions Topical retinol improves fine wrinkles associated with natural aging. Significant induction of glycosaminoglycan, which is known to retain substantial water, and increased collagen production are most likely responsible for wrinkle effacement. With greater skin matrix synthesis, retinol-treated aged skin is more likely to withstand skin injury and ulcer formation along with improved appearance.
Trial Registration clinicaltrials.gov Identifier: NCT00272610
Author Affiliations: Department of Dermatology, University of Michigan Medical School, Ann Arbor. Drs Kafi and Kwak are now with the Department of Dermatology, Stanford Medical School, Palo Alto, Calif, and Dr Cho is now with the Department of Dermatology, Seoul National University, Seoul, South Korea.
Disclosure info:
Correspondence: Sewon Kang, MD, University of Michigan Medical School, Department of Dermatology, 1910 Taubman Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109 (swkang@med.umich.edu).
Accepted for Publication: October 19, 2006.
Author Contributions: Study concept and design: Kafi, Neal, Varani, Fisher, Voorhees, and Kang. Acquisition of data: Kafi, Kwak, Schumacher, Cho, Neal, Varani, Fisher, and Kang. Analysis and interpretation of data: Kafi, Kwak, Hamilton, King, Varani, Fisher, Voorhees, and Kang. Drafting of the manuscript: Kafi, Kwak, Schumacher, Neal, and Kang. Critical revision of the manuscript for important intellectual content: Kafi, Cho, Hamilton, King, Varani, Fisher, Voorhees, and Kang. Statistical analysis: Hamilton and King. Obtained funding: Kafi, Voorhees, and Kang. Administrative, technical, and material support: Kafi, Kwak, Schumacher, Cho, King, Neal, Varani, Fisher, Voorhees, and Kang. Study supervision: Kafi, Voorhees, and Kang.
Financial Disclosure: Drs Fisher, Kang, Varani, and Voorhees are named inventors on an issued patent application concerning methods of treating skin aging. They will receive royalties under the University of Michigan's Intellectual Property Policy in the event that a commercial license is signed and a product is sold. This article describes research that was part of the basis of the approved application.
Funding/Support: This study was supported in part by grants from the Babcock Endowment for Dermatologic Research, the Merck-American Federation for Aging Research (Dr Kafi), Alpha Omega Alpha Student Research Fellowship (Dr Kafi), and the National Institutes of Health (K24, Dr Kang).
Author Affiliations: Department of Dermatology, University of Michigan Medical School, Ann Arbor. Drs Kafi and Kwak are now with the Department of Dermatology, Stanford Medical School, Palo Alto, Calif, and Dr Cho is now with the Department of Dermatology, Seoul National University, Seoul, South Korea.
Thoughts?
Take care.
