2 replies to this topic

[s123]

In his book dr. de Grey says that it’s impossible to prevent the formation of AGEs by altering your diet. But it’s possible to change to amount of each AGE individually (by altering your diet you will only form other AGEs not less AGEs). But what if you combine alagebriumchloride with a diet that sifts the kind of AGEs to AGEs that are breakable by alagebriumchloride. For example: MOLD is breakable by alagebriumchloride but glucosepane not. If you digest carbohydrates your body produces more glucosepane and if you digest more fats and proteins your body will produce more MOLD. So if you ate a carbohydrate poor and fat and protein rich diet than your body will produce more AGEs that are breakable by alagebriumchloride. So the best way is combining a diet and alagebriumchloride.

The AGEs (glucosepane and MOLD) are random chosen, I have not had the time to look it up.

What do you think about my idea?

[niner]

Interesting idea, s123. I don't know how much you can shift your AGEs exactly, but I think there's something to the idea. I think that Aubrey is being kind of rigid there, if that's really what he said (or meant), because anything that reduces your average blood sugar is going to reduce glycation. That's why diabetics have such a problem with it. If we eat a low glycemic diet, that has to help, but I think maybe what Aubrey was getting at is there's a certain level of glucose that you need to maintain, so there is always going to be a baseline level of glycation. However, the avoidance of large postprandial glucose spikes will reduce glycation a great deal in non-diabetics.

[John Schloendorn]

One problem with that is that nobody has ever managed to detect the AGE that alagebrium is supposed to break in people...