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Deprenyl finally a nootropic that works!


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124 replies to this topic

#121 Lufega

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Posted 08 September 2016 - 02:46 AM

 

I will report back after the first month. I wanted to comment though, be careful not to take it late in the day. I've been sleeping in lately and take it after Noon. This stuff keeps me up past 4 AM. Yesterday I decided not to use it to try and regulate my sleep pattern. I also did not use any Tyrosine either. What a mistake! I was moody...lashed out at my brother over something petty. I felt tired, down and had no motivation. I was up until the crack of dawn anyways. This morning, I felt horrible! I felt depressed, anxious, tired, moody, you get the idea. I took 2 drops and 1 gram tyrosine and I feel amazing again.

I normally feel the effect of reduced dopaminergic activity. This is something I have to continually tweak to be functional. I wonder if my experience was that, or maybe deprenyl has some kind of rebound effect. But I doubt it. I might stay on two drops for a while. I am 30 years old but I know I have problems with dopaminergic function (i.e. NO motivation, social anxiety, etc.) I hope that's ok.

 

Well, it's almost eight years too late responding to you, but in the literature taking the MAO-B inhibitors like L-deprenyl together with a dopamine enhancer (usually it is L-Dopa) has very bad outcomes.  I believe the research reports have been that this combination shortens life as well.    While I doubt they tested tyrosine specifically, I still think that is cautionary.   I would choose one approach or the other, not both.

 

 

8 years!  Thanks for the response anyway.  I remember this event well.  Deprenyl stopped working after using it a short while and put me in a rut that lasted a while.  I fazed out of it eventually.



#122 X_Danny_X

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Posted 08 September 2016 - 03:05 PM

dude,  what about Raseligine???? 



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#123 Omega 3 Snake Oil

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Posted 25 September 2017 - 04:24 AM

I was on deprenyl for close to four years. Gradually reduced my dose from 10mg to 1.25 daily. I'm thinking of going back on, I need its neuroprotective properties now more than ever. What herbals are unsafe to take with it, assuming I use a low dose of maybe 2.5mg?  St. John's Wort and 5HTP are out. What else?



#124 Ben

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Posted 29 September 2017 - 04:11 PM

 

 

8 years!  Thanks for the response anyway.  I remember this event well.  Deprenyl stopped working after using it a short while and put me in a rut that lasted a while.  I fazed out of it eventually.

 

 

I had exactly the same experience. I experimented with it for about 6 years off and on. 



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#125 John250

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Posted 28 April 2018 - 06:54 PM

What is the current update on this drug? I was diagnosed with borderline personality disorder and my therapist gave me Lexapro,lamictal And trileptal. Was on lexapro for 7 years, lamical and trileptal for about 2 years. I told myself I don’t want to be on any medication as it’s not needed for borderline personality disorder only cognitive therapy is so I weaned myself off The lamical and trileptal over a 3-4mo period. Last dose was about 6mo ago. I weaned off the lexapro over a 6mo period. Last dose about 3mo ago. The only thing I am on now is Adderall since the lethargy was so bad with those he prescribed me adderall. That is by far the one drug I wish I never touch. The first time I took it I realized nothing would ever feel the same without it and I needed more and more. this is the one that I can’t kick. I need it to function and I need more and more and I can see myself getting into a bad path. I have 2 boy toddlers and a demanding wife so I’m exhausted all the time and need this even more now but I don’t want long-term neurotoxicity and even though I supplement with a ton of neuroprotective supplements I’m sure damage will still occur. I know I need to taper off of it so I’m wondering if deprenyl would be good to add to help with the withdrawal? And I need to figure out the dosing of deprenyl while still on adderall. I take more adderall than I should about 60-90mg day. I need to wean to 40-60mg for a few weeks then 20-40 for a few weeks then 10-20 then 5-10 then quit. Would it be fine to start deprenyl now at a low dose say 1mg/day and would it even help with the cravings and withdrawal? Thanks




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