Just speculating when thinking about how the CR effect works in humans.
Let's say we have 2 twins of average size.One consumes the average 3000 calories a day while the other is a obese binge-eater who consumes in the range of 5000-7000 calories a day.However he has good genes and luckily escapes the killers like heart disease etc (just like in the case of the king of Tonga who lived to the age of 88 although weighing over 400 lbs for large parts of his life and never under 300.Wouldn't they have similar lifespans and let's say die of organ failure due to generalized old age weakness or whatever people die of in nursing homes.
Obesity causes a lot of damage as far as I understand but it doesn't "accelerate aging" after all so that you end up frail and wrinkly in nursing homes in your 50's.And since the one eating 3000 calories a day doesn't activate any potential longevity enhancing activities due to cr he would also age normally.
As far as I understand CR works due to the body's response to upgrade itself for maintenance when calories are low and therefore I conclude that an athlete of the same size eating 5000 calories a day during all his life and exercising would live just as long if not even longer than the person eating 3000 calories a day but being sedentary.
Am I thinking right?Comments would be appreciated