Macronutrient composition makes a difference as well. Serum saturated fat and inflammation go down on a low carb diet, even while serum O6 goes up. http://www.ncbi.nlm....pubmed/18046594
A follow up showed that, in the context of a low carb diet, varying the amount of saturated fat had little effect on the amount of saturated fat in the blood.
http://www.ncbi.nlm....?report=classic