Consider this an actively updated document. Please post your suggestions, updates, changes, additions, etc.
My grandma was admitted to the hospital August 19 for cancer surgery. The operation took place Thursday of that week and seemed to go well. However, either during surgery or in recovery she suffered a stroke.
As a result of the stroke, she has had expressive aphasia, meaning she has had difficulty speaking. She initially also had some cognitive issues. In the days since the surgery, she has been recovering slowly but steadily from both the operation and the stroke. We did learn last week that one of 12 lymph nodes that were tested came back positive and she will have to have radiation treatment for this.
Our immediate concern, though, has been dealing with the stroke.
read more of her story here.
...
So it's been a couple months now and she has improved dramatically in her recovery from the stroke, though not fully.
We now must attack this cancer, and I need your help.
One thing we are seriously debating is whether to go through with radiation therapy. We are leaning against it. Any advice on this point would be greatly appreciated. (editted: last we have heard, radiation therapy was recommended, not chemo. I think I have convinced involved parties to push her oncology appt. up ASAP)
The second point is creating an anti-cancer regime. edit: apparently she is taking a whole long list of drugs. Because of that, I'm thinking we are going to have to meet with some kind of holistic doctor of some sort in order to figure out what goes with what and what we can do and can't, etc. I dunno anything about doing that but hopefully we can figure that out. I'll try to document here what she is taking and how everything interacts.
I have done a meta-analysis of DukeNukem and TheFirstImmortal. Here is what I have so far:
--- Cancer ---
Radiation therapy:
.................General info
.................Targeted Radiation Therapy is Successful
.................options?
Chemotherapy:
.................info
.................options?
Multi-Vitamins:
.................options?
Anti-Oxidants:
................black raspberries
................................http://www.sciencedaily.com/releases/2008/08/080827163933.htm
................................Eclectic Institute Black Raspberry | unknown quality | 90 / 3-8 | 300 mg | $10.53 | link
................................Swanson Black Raspberry | unknown quality | 60 / 1 | 425 mg | $3.99 | link
................................other options?
................................best option?
................green/white Tea
................................LEF Mega Green Tea Extract (Lightly Caffeinated) | unknown quality | 100 / 1 | see link for potency | $28.00 | link
................................Now Foods EGCg Green Tea Extract | unknown quality | 180 / 1-2 | see link for potency | $14.27 | link
................................various
................................best option?
................resveratrol
................................10 mg/kg
................................1g daily (dukenukem)
................................170mg/kg 2-3x daily (missminni)
................................I think five or 6 grams in one dose is the maximum dose that would show increased blood levels. However, it could administered twice or even three times a day to result in higher sustained levels. So 15 grams a day in three divided doses is a possibility, as long as there are no intolerable side effects. I would work up to such a dose for myself, doubling dosage every two days. I do not think such a high dose would be needed for more than a few weeks at most, and that a maintenance dose of a few grams a day will be all that is needed. (maxwatt)
................................LEF Resveratrol | unknown quality | 60 / 4-45? | 250 mg | $34.50 | link
................................Vital Prime Resveratrol | unknown quality | 100 / 1-15 | 1 g | $63 | link
................................Vital Prime Resveratrol | unknown quality | 500 / 1-15 | 1 g | $310 | link
................................other options?
................................best option?
................blueberry
................................LEF Blueberry Extract | unknown quality | 60 / 1 | see link for potency | $22.50 | link
................................other options?
................................best option?
................pomegranate
................................LEF Pomegranate Extract | unknown quality | 30 / 1 | see link for potency | $19.50 | link
................................other options?
................................best option?
................cocoa
................................iHerb Cocoa Bean Extract | unknown quality | 1180 / 20 | see link for potency | $8.39 | link
................................other options?
................................best option?
................Intraveneous vitamin C
................................any ideas?
................................other options?
................................high dose vit C interferes with chemotherapy treatments | link
................tomato (lycopene)
................................Now Foods Lycopene | unknown quality | 50 / 1 | 20 mg | $16.78 | link
................................21st Century Health Care Lycopene | unknown quality | 60 / 1 | 25 mg | $7.99 | link
................................best option?
................apple
................................options?
................others?
Supplements:
................Selenium
................................LEF Super Selenium Complex & Vitamin E | unknown quality | 100 / 1 | 200 mcg | $12.00 | link
................................Healthy Origins Seleno Excell Selenium | unknown quality | 180 / 1 | 200 mcg | $3.68 | link
................................various
................................best option?
................Vitamin D3
................................LEF Vitamin D3 | unknown quality | 250 / 1 | 1000 IU | $12.50 | link
................................Natural Factors Vitamin D3 | unknown quality | 90 / 1 | $5.97 | link
................................various
................................best option?
................IP-6
................................IP-6 is a highly effective metal binder and deprives cancer/tumor cells of iron and copper, two primary growth requirements
................................2-4 grams daily
................................45 minutes away from meals or other supps containing minerals. I'd try to do half early in the day, and half before bed (dukenukem)
................................Jarrow Formulas IP6 Inositol Hexaphosphate | unknown quality | 120 / 1-8 | 500 mg | $7.67 | link
................................various
................................best option?
................Fish oil
................................Jarrow Formulas EPA-DHA Balance | unknown quality | 240 / 2-5 | 420-210 mg | $23.07 | link
................................other options?
................................best option?
................CoQ10 / Ubiquinol
................................is anti-cancer?
................................options?
................Quercetin
................................LEF Quercetin | unknown quality | 100 / 1 | 500mg | $17.95 | link
................................Now Foods Quercetin | unknown quality | 100 / 1 | 500mg | $9.50 | link
................................various
................................best option?
................Melatonin
................................LEF Melatonin | unknown quality | 60 / 1 | 10 mg | $28.00 | link
................................Jarrow Formulas Melatonin Sustain | unknown quality | 120 / 1 | 1 mg | $6.57 | link
................................various
................................best option?
................others?
Combination Formulas:
................options?
Spices:
................Garlic
................................options?
................Curcumin
................................options?
................Turmeric
................................options?
................Capsaicin
................................options?
................Ginger
................................options?
................others?
Dietary and Behavioral Optimization and Other Advice:
................NO DAIRY.
................No sugar, candy, cookies, cake, fruit juice, or other sugary foods.
................................The safest artificial sweetener is saccharine (dukenukem).
................................Stevia is a better sweetener than saccharine (missminni).
................No starches: no rice, bread, potato, or pasta (only raw veggies).
................................Except Ezekiel 4:9® Bread
................No red meat.
................15 minutes of sun per day.
................good fats/oils
................Starved for better chemo
................chronotherapy
................no white egg (methionine=fuel for cancer)
................Reduce stress
................others?
---
--- Stroke (not included above)---
................Low Dose Aspirin
................................options?
................Ginkgo Biloba
................................options?
................Hydergine
................................options?
................Piracetam
................................options?
................others?
---
In addition, I have collected some notes on other points that I haven't reviewed yet. I need some advice on whether these have proven anti-cancer properties and would be worth the effort:
.................high-potency fluoride mouth wash
.................Ave: http://www.avemarusa.com/index.html
.................Lactoferrin mega doses (3 grams daily)
.................I-C-3 mega doses
.................Flax seed lignans
.................Tagamet
.................Boswellia / 5-Loxin
.................Gamma Tocopherol w/Seseame Lignans
.................Grape Seed Extract
.................Phyto-Food (cruciferous vegetable concentrate)
.................Silibinin
.................GLA (gamma-linolenic acid)
.................Silymarin
.................emodin
.................Ellagic acid
.................Metformin
.................St John's Wort extract
.................others?
Non-comprehensive Warnings:
Resveratrol
Cell culture studies suggest that resveratrol is a weak inhibitor of the liver metabolism system P450 3A4, but this interaction is of unknown significance in humans. Ingestion of large amounts of resveratrol may increase blood levels of drugs known to be metabolized via CYP3A4. This would include statins, calcium channel blockers, certain immunosuppressant drugs (e.g. cyclosporine), and drugs for erectile dysfunction (e.g. sildenafil). Caution is advised if used concurrently with anticoagulants or antiplatelet drugs such as Clopidogrel (Plavix).
Curcumin
Do not take curcumin if you have a bile duct obstruction or a history of gallstones. Taking curcumin can stimulate bile production.
Consult your doctor before taking curcumin if you have gastroesophageal reflux disease (GERD) or a history of peptic ulcer disease.
Consult your doctor before taking curcumin if you take warfarin or antiplatelet drugs. Curcumin can have antithrombotic activity.
Always take curcumin with food. Curcumin may cause gastric irritation, ulceration, gastritis, and peptic ulcer disease if taken on an empty stomach.
Curcumin can cause gastrointestinal symptoms such as nausea and diarrhea.
EPA/DHA
Consult your doctor before taking EPA/DHA if you take warfarin (Coumadin). Taking EPA/DHA with warfarin may increase the risk of bleeding.
Discontinue using EPA/DHA 2 weeks before any surgical procedure.
Garlic
Garlic has blood-thinning, anticlotting properties.
Discontinue using garlic before any surgical procedure.
Garlic can cause headache, muscle pain, fatigue, vertigo, watery eyes, asthma, and gastrointestinal symptoms such as nausea and diarrhea.
Ingesting large amounts of garlic can cause bad breath and body odor.
Green Tea
Consult your doctor before taking green tea extract if you take aspirin or warfarin (Coumadin). Taking green tea extract and aspirin or warfarin can increase the risk of bleeding.
Discontinue using green tea extract 2 weeks before any surgical procedure. Green tea extract may decrease platelet aggregation.
Green tea extract contains caffeine, which may produce a variety of symptoms including restlessness, nausea, headache, muscle tension, sleep disturbances, and rapid heartbeat.
Vitamin A
Do not take vitamin A if you have hypervitaminosis A.
Do not take vitamin A if you take retinoids or retinoid analogues (such as acitretin, all-trans-retinoic acid, bexarotene, etretinate, and isotretinoin). Vitamin A can add to the toxicity of these drugs.
Do not take large amounts of vitamin A. Taking large amounts of vitamin A may cause acute or chronic toxicity. Early signs and symptoms of chronic toxicity include dry, rough skin; cracked lips; sparse, coarse hair; and loss of hair from the eyebrows. Later signs and symptoms of toxicity include irritability, headache, pseudotumor cerebri (benign intracranial hypertension), elevated serum liver enzymes, reversible noncirrhotic portal high blood pressure, fibrosis and cirrhosis of the liver, and death from liver failure.
Vitamin C
Do not take vitamin C if you have a history of kidney stones or of kidney insufficiency (defined as having a serum creatine level greater than 2 milligrams per deciliter and/or a creatinine clearance less than 30 milliliters per minute.
Consult your doctor before taking large amounts of vitamin C if you have hemochromatosis, thalassemia, sideroblastic anemia, sickle cell anemia, or erythrocyte glucose-6-phosphate dehydrogenase (G6PD) deficiency. You can experience iron overload if you have one of these conditions and use large amounts of vitamin C.
Vitamin D
Do not take vitamin D if you have hypercalcemia.
Consult your doctor before taking vitamin D if you are taking digoxin or any cardiac glycoside.
Only take large doses of vitamin D (2000 international units or 50 micrograms or more daily) if prescribed by your doctor.
See your doctor frequently if you take vitamin D and thiazides or if you take large doses of vitamin D. You may develop hypercalcemia.
Chronic large doses (95 micrograms or 3800 international units or more daily) of vitamin D can cause hypercalcemia.
Individuals consuming more than 2,000 IU/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement. Toxicity is very unlikely in healthy individuals at a dose of less than 10,000 IU. Vitamin D supplementation is contraindicated in individuals with hypercalcemia (high blood calcium levels). People with kidney disease, certain medical conditions (such as hyperparathyroidism, lymphoma, sarcoidosis), and those who use cardiac glycosides (digoxin) or thiazide diurectics should consult a physician before using supplemental vitamin D.
Vitamin E
Consult your doctor before taking vitamin E if you take warfarin (Coumadin).
Consult your doctor before taking high doses of vitamin E if you have a vitamin K deficiency or a history of liver failure.
Consult your doctor before taking vitamin E if you have a history of any bleeding disorder such as peptic ulcers, hemorrhagic stroke, or hemophilia.
Discontinue using vitamin E 1 month before any surgical procedure.
other warnings?
Questions:
................Are there any harmful interactions?
................What am I missing?
................Which are the most important of all the things in this meta-analysis?
................Where can I buy these things in good quality for a low price?
................What is the quantity, frequency, and timing that these things should be taken?
................other questions?
I'm hoping through the combined power of this community we can create a comprehensive cancer fighting information warehouse as an official ImmInst project.
This open-source information warehouse should ideally address everything I've brought up here, and could be kept in a single location and continuously updated for distribution to anybody and everybody who is seriously trying to overcome cancer.
I think this could be a very major achievement for the Immortality Institute.
Anything related to the stroke would also be appreciated- perhaps in addition to a cancer fighting info warehouse we can do one for strokes as well.
Any small piece of individual advice or words of enouragement are of course appreciated.
Thanks.
Edited by Savage, 13 October 2008 - 01:16 AM.