- DMAE pyroglutamate: http://www.ncbi.nlm....pubmed/19756528
- Coffee contains pyroglutamate: http://www.ncbi.nlm....pubmed/16546340
- Activates glutamate binding sites to a lesser degree than glutamate or aspartate. High doses block Adrenal receptors: http://www.ncbi.nlm..../pubmed/1976055
- Massive doses have cholinergic effects in rats: http://www.ncbi.nlm..../pubmed/3448611
- Comparison of Nooglutyl & L-pyroglutamyl-D-alanine: http://www.ncbi.nlm..../pubmed/8704601
- L-pyroglutamyl-D-alanine restores LTP: http://www.ncbi.nlm..../pubmed/7609900
- Possibly Regulates Thyroidism: http://www.ncbi.nlm....pubmed/21330373
My conclusion is that this thing is more or less natural, and it has less toxicity than glutamate or aspartate. You'd get more brain damage from drinking diet soda than taking the supplement.
Edited by devinthayer, 14 November 2011 - 04:11 PM.