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Cerebrolysin


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#1741 SLR2009

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Posted 13 November 2013 - 10:37 PM

I greatly appreciate the advice. Does it reverse brain damage? Will it get my vision back to normal? I'm seeing a Neurologist soon. I'm also looking very strongly into the Hyperbaric Oxygen Chamber. Which do you think would be better?

Thanks again.

Edited by SLR2009, 13 November 2013 - 10:38 PM.


#1742 Braziliandude

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Posted 14 November 2013 - 05:15 PM

cerebrolysin has saved my life..no exageration!
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#1743 dunkiez

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Posted 17 November 2013 - 03:51 PM

Hi all,

I just heard about this drug from a doctor friend, she's a middle aged woman and apparently takes it once a year. She didn't mention the dosage, but i'm assuming its 1 injection ~5ml.

Is this too small a dosage to be effective?

I'm a young healthy man in my early twenties running my own business. It gets mentally draining working long hours and having to make decisions and design strategies on a daily basis. Basically dealing with mentally challenging tasks and stress.

I'm starting piracetam at 1600mg X 2 doses daily too.

Please let me know your thoughts on the recommended cerebrolysin dosage required for healthy individuals and relevant studies if any.

Thanks :laugh:

#1744 Flex

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Posted 17 November 2013 - 05:05 PM

A good reminder to have in mind, by russianBEAR:

Well, if you guys are still interested in hearing all about Cerebrolysine and how it compares to other similar drugs...

I live in Russia so we have the widest possible variety of nootropics available mostly over the counter, and mostly without prescription (pharmacies are all about cash here).

Basically I've done pretty much every "smart drug" you can name both as part of some kind of a "monthly cycle/course" alone, as well as in a variety of combinations.

As far as Cerebrolysine goes, yeah it's expensive as **** and it's also very effective. I've worked an incredibly stressful job where you have to work very very fast under enormous amounts of pressure, and one even small mistake can lead to you being fired or worse. Basically doing something that takes 10-15 minutes in 30 seconds was the absolute norm in the workplace at the time (24-hour television news, working in the directors gallery where the stuff airs from, what can I say it was crazy, glad I moved to a lower-stress department).

I was taking up to 10 ml of cerebrolysine daily at work though I/M injections, easily for a good 6 months if not more. (Usually in 2 injections, although I've shot 10ml straight up before in one large syringe) Since I worked in 4-day shifts, I'd usually go 4 days on and then 4 days off to cool off my neurons Posted Image That easily allowed me to handle all the stresses, and I was one of the best at that particular job. Despite having abused illegal drugs in the past and being a frequent cannabis smoker, I experienced little to no "stoner burnout" and was able to concentrate and perform tasks faster than most of my colleagues at the same experience level. After a long 12-hour work day, after which a normal brain turns to mush, I was still fresh and eager to go out with friends/ see girls etc, while otherwise I'd be drained and only wanting to sleep.

So instead of rambling on further, let me just break down some effects and side-effects, short and long term:

-This stuff has a MARKED anti-depressant effect. You basically feel like back in the happiest moments of your childhood. Everyone has had one of those days when they're just "on fire" and "on top of the game". With Cerebrolysine, pretty much every day is like that - you're not overly happy or vegetated like off standard anti-depressants, but you're "on point" at whatever you do. Stuff like your subconscious and conscious fears all go right out of the window, and it has a bit of a socially-inhibiting effect too.

-If you thought weed gets you the munchies, wait till you try this stuff. When you first start on this cycle, you get hungry as a SAVAGE. I usually eat just enough to be full, not overly gorged, but this stuff had me tearing up huge meals and not even feeling incapacitated by everything I just ate. I'd attribute this to the fact that with all the additional peptides and stuff, your body needs more nutrition. Sort of like adding B-vitamins to stuff like Pyritinol or even good old 5-HTP.

-Cerebrolysine helps alleviate most, if not all symptoms of post-intoxication syndrome for illicit drugs. I once gave my friend a shot after his most recent cocaine binge and he turned from a pale shadow who was about to pass out back to his normal self - energetic, enthusiastic, and motivated. Plus his foul mood and edginess were completely gone. It also seems to ease the alcohol-related hangover better than some other substances (although many nootropics are much better for that IMO since they're GABA-active). My other friend also liked taking it as a "corrector agent" for other nootropics/supplements, claiming it helped alleviate certain unwanted effects of piracetam, while preventing one from overloading on one particular amino acid too much. I personally avoid ALL other substances when doing cerebrolysine. It simply overshadows them all for me.

-They definitely put some kind of a painkiller in there. Shooting cortexin (which is similar, but I like it alot less, as it "vegetates" and sedates me too much to where I'm more mentally capable, but simply don't care) without a novacaine solution is literally a huge pain in the rear, while shooting straight cerebrolysine into my tiny tricep with a huge needle made my whole arm go numb for a short time, like an anastetic would.

-I've measured my blood pressure several times before and after the injections, and there is a slight blood pressure elevation. If you inject too fast, the heart rate jumps and you may sweat profusely. However it gives you a nice sort of a "rush" to where you feel very relaxed, but not incapacitated or drugged by any stretch of imagination. The headaches are there, but are very slight, and usually start about 2-3 hours after the injection.

-The long-term effects aren't so pleasant. There is an increasing feeling of "mounting personal hell" as I like to call it. Basically, all the negative traits of one's character seem to be unnaturally emphasized and underlined in your mind, while the positives seem little and insignificant. It doesn't really manifest itself in a severe form to others, but you may feel "grumpy" and "dissatisfied" even when you seem to be razor-sharp mentally. A good comparision would be some rich spoiled kid who has everything throwing tantrums and breaking stuff, just because he is rich and spoiled. Several of my friends reported very similar mental side effects. This is what initially led me to stop taking it by "tapering down" (I don't think it's a good method by the way, but since I was doin it daily for a while I decided for a slower descent). A .5 ml less every day for several days, then a week at 1ml and then 0.5 and then you're shooting colored water for placebo effects Posted Image

- Some people report a HUGE boost in their sexual activity. I noticed only a slight boost Posted Image

- When you're off the cerebrolysine, you feel like it's a bad day for no reason (see above having a top of your game day for no reason lol). I didn't notice any significant negative long-term effects on my cognitive processes. On the contrary I seem to be able to concentrate better at any time, without taking any substances, or even after smoking a lot of weed. I'm now able to "zone in" on something more completely and do better at focusing.

-This stuff has very strong and powerful overall effects, it is the most effective out of injectable nootropics/smart drugs that I've tried. Cortexin doesn't even come close, and various Cerebrolysine derivatives (we ahve a Cerebrolysate here) are nothin more than cheap imitations.

I've decided for another mini-cycle just now, about 3 years after that last lengthy episode. I'm sticking to what the doctors here recommend: 5ml every OTHER day. Seems to be the correct dosage and schedule.

I hope it doesn't sound too much like promo for the Austrian pharmaceuticals company which makes this stuff. It's really not somethin you want to mess around with if you don't know what you're doing.


Well all this is true as well.



Could please someone explaine me more precisely how or if Cerebrolysin spoils the character ?

Is it severe ?

And could please someone tell their own experiences ?

#1745 Heh

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Posted 17 November 2013 - 09:34 PM

Hi all,

I just heard about this drug from a doctor friend, she's a middle aged woman and apparently takes it once a year. She didn't mention the dosage, but i'm assuming its 1 injection ~5ml.

Is this too small a dosage to be effective?

I'm a young healthy man in my early twenties running my own business. It gets mentally draining working long hours and having to make decisions and design strategies on a daily basis. Basically dealing with mentally challenging tasks and stress.

I'm starting piracetam at 1600mg X 2 doses daily too.

Please let me know your thoughts on the recommended cerebrolysin dosage required for healthy individuals and relevant studies if any.

Thanks :laugh:

Cerebrolysin sounds like it's definitely up your alley (high stress, business owner, etc). I'd say 5ml/day (up to 10ml if really mentally stressed) should be good enough. Once a quarter should work, but you could inject more frequently (up to once every.. other month) if you feel the effect wearing off.

Edited by Joel, 17 November 2013 - 09:36 PM.


#1746 Sholrak

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Posted 18 November 2013 - 02:29 AM

I would try 5 ml every 48 hours. Seems the razonable way to me, as a dose's effect lasts almost two days. Definitely the path to go with this. This is not a substance you wanna 'burn' continously like any regular with "daily/weekly routine" schedule, but a one you wanna slowly enjoy and adjust over the time.


It's a big missunderstanding it spoils the character in any form. It doesn't spoils, it enhances it. But long term has it's own contras, ie. you can feel you are aware of almost everything a human mind should/could be. It's oppressing if you do too much of it, how you can see every detail in the picture. Nothing to worry about really as the benefits hugely counter the contras :)

There are two modes: 5 days on/2 off during 4 weeks AND every other day during a month (15 doses). In any case, you'll have to wait two months off before restarting wiht these cycles.

#1747 SLR2009

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Posted 18 November 2013 - 03:49 AM

I appreciate all the info. Does Cerebrolysin regrow brain cells if they were damaged?

#1748 Flex

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Posted 18 November 2013 - 04:37 PM

I would try 5 ml every 48 hours. Seems the razonable way to me, as a dose's effect lasts almost two days. Definitely the path to go with this. This is not a substance you wanna 'burn' continously like any regular with "daily/weekly routine" schedule, but a one you wanna slowly enjoy and adjust over the time.


It's a big missunderstanding it spoils the character in any form. It doesn't spoils, it enhances it. But long term has it's own contras, ie. you can feel you are aware of almost everything a human mind should/could be. It's oppressing if you do too much of it, how you can see every detail in the picture. Nothing to worry about really as the benefits hugely counter the contras :)

There are two modes: 5 days on/2 off during 4 weeks AND every other day during a month (15 doses). In any case, you'll have to wait two months off before restarting wiht these cycles.


Thx :)

#1749 Braziliandude

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Posted 18 November 2013 - 07:44 PM


SLR2009 thats what it looks like...I cant tell you exactly...what I can tell you is that it just fixed a part of my brain that was demaged however its not enough, and i will probably try ibogaine to do that.


#1750 Flex

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Posted 19 November 2013 - 08:35 PM

Thx.

I´m just also a bit concered (dont misunderstand me or take it as a affront) to inject something form an animals brain in mine.

And that someone somewhen would acclaim that Cereborlysine done something irreversible to me like changed my mRNA.

I know how it sounds( this is just all me), but the thought that there is something that I could´nt not reverse it, makes me a bit panic.

could you or somebody may clear my last concerns ?

BTW I have listed my problems here
http://www.longecity...ethylphenidate/

#1751 Braziliandude

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Posted 21 November 2013 - 01:22 AM

you have done cocaine and smoked pot...believe me, cerebrolysin will do nothing but help you to get better.

Edited by Braziliandude, 21 November 2013 - 01:23 AM.


#1752 Perception-Is-Reality

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Posted 21 November 2013 - 02:35 AM

SLR2009 thats what it looks like...I cant tell you exactly...what I can tell you is that it just fixed a part of my brain that was demaged however its not enough, and i will probably try ibogaine to do that.


Do you have a reliable source for ibogaine?

#1753 Braziliandude

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Posted 21 November 2013 - 03:01 AM

it seems like this is a reliable source http://www.ibogaworld.com/ its from holland

#1754 Flex

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Posted 22 November 2013 - 11:50 AM

I´ve ordered once back in 2008 form https://maya-ethnobo...bernanthe-iboga

It is( or was at least then) reliable. It was a powder with little crystals and worked, but was expensive.

I have to warn you! even in therapeutic doses it can cause fatal collapse of the cardiovascular system due overactivation.. or something like that (forgot what exactly it was)

Therefore the Shamans induce a Trance state to make it safe.

Please investigate further information before usage!!

Further: to low dosage wont increase GDNF in the VAT
and too much would be toxic to purkinje cells in the Cerebrum( this is a region who compesates loss of PFC function in cases of e.g. longterm cocaine usage)

Edited by Flex, 22 November 2013 - 11:54 AM.


#1755 SLR2009

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Posted 22 November 2013 - 11:24 PM

What dosage should I take for the brain damage which I have?

Would 10 ml be sufficient or would 20 ml (or more) be what I would need?
I should do this 5 days a week for 1 month? I then stop for 2 months and start the treatment again if I wanted?

I think I feel better going off my anti-depressants before I start this.

I can't do the IV myself, who would be able to do this for me? A hospital?

#1756 jennster

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Posted 22 November 2013 - 11:31 PM

Is there anything similar in effect that does not have to be injected? I really wanted to try this IN but now I see that many are saying it is unsafe so I have reservations with using that method. Any suggestions would be appreciated.

#1757 formergenius

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Posted 23 November 2013 - 09:33 PM

Case summary:
I have HPPD/DP/DR/Anxiety/Depression and cognitive dysfunction (all drug-induced), all of which were exaggerated by (stupid, I know) cocaine use 2~3 months ago
I won't go in to further detail of my situation, but let's just say I (literally) can't do much more than lie on the couch all day.
It took me 12 hours to read through this entire thread.. And even then I barely retained anything from it. (suspecting this is abnormal)
I'll elaborate further, should Cere prove to work for me.

Cerebrolysin:
I've ordered 20 x 10ml from Nootropic.eu. I figured pedal to the metal; 10ml/day 5 days on, 2 off.
I've never done intramuscular injections, and have avoided Cerebrolysin for this reason, but with the recent worsening of my condition, I've become desperate.

As I see it, it should be relatively simple. All I need is the Cerebrolysin, some alcohol swabs, disposable syringes and needles.
Either jab into lower outer thigh, or upper outer buttocks, and cycle injection sites. (and the rest of the steps which I'm aware of)

Questions:
Regarding the needle: I've been very sedentary the last year or so, hence don't have much muscle. Do I have to worry about hitting the bone with a longer needle (1.5 inch)? The website I'm ordering from doesn't have 25G 1.5 inch needles. I can get 24G 1 inch. 22G is the thinnest needle I can get with 1.5 inch length. Please advise me which would be best. Thank you.

EDIT: @jennster: NSI-189 should be similar I presume, though from what I've read it's inferior. There's also the oral Cerebrolysin version, but is much less potent. Noopept could be explored as an alternative as well.

Edited by formergenius, 23 November 2013 - 09:36 PM.


#1758 JASOG888

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Posted 24 November 2013 - 12:09 AM

I would use the 24G 1 inch ones.
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#1759 formergenius

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Posted 24 November 2013 - 09:37 AM

Thank you!

it seems like this is a reliable source http://www.ibogaworld.com/ its from holland

It is; this is where I bought mine I believe. It's paramount to have a proper set, setting, and sitter! I failed in all these regards and had a rather difficult experience. Preferably a person with a little medical background (i.e. able to reaffirm to you that your heart is fine; which may or may not do funny things one Iboga) and do it somewhere where you feel safe.

#1760 Braziliandude

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Posted 24 November 2013 - 06:14 PM

did u actually use the ibogaine? for what? whats the outcome ??

#1761 formergenius

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Posted 24 November 2013 - 08:09 PM

did u actually use the ibogaine? for what? whats the outcome ??

I did. "Reset brain" sounded quite attractive. Didn't work. PM sent. Now back on topic please :)

#1762 Sholrak

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Posted 25 November 2013 - 01:22 AM

There's not 25 G one inch? If not, follow with 24 G 1". With 1.5 inches you'll need to know when to stop the needle, while 1 inch allows you to enter the whole needle without risks.

#1763 dunkiez

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Posted 25 November 2013 - 04:02 AM

Hi all,

I just heard about this drug from a doctor friend, she's a middle aged woman and apparently takes it once a year. She didn't mention the dosage, but i'm assuming its 1 injection ~5ml.

Is this too small a dosage to be effective?

I'm a young healthy man in my early twenties running my own business. It gets mentally draining working long hours and having to make decisions and design strategies on a daily basis. Basically dealing with mentally challenging tasks and stress.

I'm starting piracetam at 1600mg X 2 doses daily too.

Please let me know your thoughts on the recommended cerebrolysin dosage required for healthy individuals and relevant studies if any.

Thanks :laugh:

Cerebrolysin sounds like it's definitely up your alley (high stress, business owner, etc). I'd say 5ml/day (up to 10ml if really mentally stressed) should be good enough. Once a quarter should work, but you could inject more frequently (up to once every.. other month) if you feel the effect wearing off.



The schedule recommended by my friend is 10ml/day 5 days on 2 days off for a total of 100ml. She does this once a year and i don't think she will give me more if I ask for it for fear of my well being.

My question is, are there any long term changes in your brain (negative/positive) or is this a kind of drug that fades as soon as you go off it?

Will I end up dumber or go back to baseline if I go off it for a prolonged period (few years)?

Also since this drug is used predominantly in older folks and people with brain damage, what's the long term effect on young healthy individuals as they approach middle- old age without continuing this drug?

Appreciate any input or researches.

#1764 SLR2009

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Posted 25 November 2013 - 05:48 AM

What dosage should I take for the brain damage which I have?

Would 10 ml be sufficient or would 20 ml (or more) be what I would need?
I should do this 5 days a week for 1 month? I then stop for 2 months and start the treatment again if I wanted?

I think I feel better going off my anti-depressants before I start this.

I can't do the IV myself, who would be able to do this for me? A hospital?


Anyone? Please help.

Edited by SLR2009, 25 November 2013 - 05:49 AM.


#1765 Ark

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Posted 25 November 2013 - 09:58 AM

I still am looking for a SAFE/bulk source to do a big cycle of cerebrolysin i had a few sources over the years airseal.com etc... but now i am ready for the big plunge. LETS DO A BULK BUY!!!!

#1766 JASOG888

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Posted 25 November 2013 - 12:22 PM

What dosage should I take for the brain damage which I have?

Would 10 ml be sufficient or would 20 ml (or more) be what I would need?
I should do this 5 days a week for 1 month? I then stop for 2 months and start the treatment again if I wanted?

I think I feel better going off my anti-depressants before I start this.

I can't do the IV myself, who would be able to do this for me? A hospital?


Anyone? Please help.


Why IV? IM should be fine and you would not need to go to a hospital.

#1767 formergenius

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Posted 25 November 2013 - 12:34 PM

@Sholrak: Nope. But I opted for buying both in the end :)
@SLR: It would help if you could specify "brain damage". I also don't know what dose would be best for me, however I feel very damaged, hence have decided to do 10ml a day 5on7off. Indeed a month would be sufficient to gauge efficiency. After that, you can decide how to continue. You don't have to do IV: do IM. It's relatively easy, and much safer. Indeed a hospital or a doctor could do this for you, but would require some effort, time, and finances, to set up. IDK about the AD's.

I've made my own simplified how-to guide for IM injections. I made it because I wanted it to fit 1 page, so that I can print it and place it on the wall. And writing up things in your own words helps you learn, right? Anyway, it was based of off this post and you can download it here (no guarantees of accuracy; this will be my personal method). If anyone can give me some feedback on whether it's more or less the way to go, that would be great :)

#1768 Heh

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Posted 25 November 2013 - 02:25 PM

Hi all,

I just heard about this drug from a doctor friend, she's a middle aged woman and apparently takes it once a year. She didn't mention the dosage, but i'm assuming its 1 injection ~5ml.

Is this too small a dosage to be effective?

I'm a young healthy man in my early twenties running my own business. It gets mentally draining working long hours and having to make decisions and design strategies on a daily basis. Basically dealing with mentally challenging tasks and stress.

I'm starting piracetam at 1600mg X 2 doses daily too.

Please let me know your thoughts on the recommended cerebrolysin dosage required for healthy individuals and relevant studies if any.

Thanks :laugh:

Cerebrolysin sounds like it's definitely up your alley (high stress, business owner, etc). I'd say 5ml/day (up to 10ml if really mentally stressed) should be good enough. Once a quarter should work, but you could inject more frequently (up to once every.. other month) if you feel the effect wearing off.



The schedule recommended by my friend is 10ml/day 5 days on 2 days off for a total of 100ml. She does this once a year and i don't think she will give me more if I ask for it for fear of my well being.

My question is, are there any long term changes in your brain (negative/positive) or is this a kind of drug that fades as soon as you go off it?

Will I end up dumber or go back to baseline if I go off it for a prolonged period (few years)?

Also since this drug is used predominantly in older folks and people with brain damage, what's the long term effect on young healthy individuals as they approach middle- old age without continuing this drug?

Appreciate any input or researches.

I think it would be good to do it for one month. The effect eventually wears off after about 2-3 months, hence the reason for redoing it. I think there is a graph somewhere that shows the steady decline after stopping, but I can't remember where it is or what it was measuring.

#1769 Keizo

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Posted 25 November 2013 - 03:20 PM

Today is the third day of my second five-day cycle. I'm dosing 10ml per day with a 2 day break every five days. The effects range from "extremely noticeable" to "not such a big deal". Here's a breakdown of my experience...

[...]

Any thoughts on these experiences? I read something about CERE depleting glutathione, so I bought some NAC as well as sublingual glutathione and I'm waiting for it in the mail now.

How did you feel before starting this routine?

I started taking 5ml IM 2 days ago, experienced a very noticeable effect. Skipped yesterday, partly because of an allergic reaction (some rashes and slightly tight throat) I didn't want to build up, and today the effects are more mild except for the initial rush if one can call it that. (I didn't get any allergic reaction, though, I took the antihistamine earlier this time.)

I'm experiencing some sort of tired feeling, more today, but this is the same as I have experienced before starting with Cerebrolysin. It's just slightly different, and it seems to go away if I start doing things. Overall the positive energy, concentration, and so forth overshadows anything else. Most interestingly I feel like I did when I was a kid, on some level.


One thing that is concerning and might fit into the "mounting personal hell" description given by russianbear, and some ramblings I saw someone type... Is that I experienced music more as a collection of different parts that I could all discern easily, and their intent and so forth... I.e. it seemed a bit hard to just enjoy it.
Similarly yesterday I experienced this rush of thoughts wherein I lay to much value on the thoughts themselves, I became attached to them and the goal became for a while to follow them wherever they lead.
Well basically I became my old self I guess, only more organized in my thoughts. But so there might be the potential for manic behaviour. However it also seems to have this calming effect that can facilitate empathy and moderation.

By the way I am using it to combat protracted withdrawal from benzodiazepines, or more specifically the cognitive defects. My mind has been fairly blank for a while.

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#1770 Heh

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Posted 25 November 2013 - 03:26 PM

Hi all,

I just heard about this drug from a doctor friend, she's a middle aged woman and apparently takes it once a year. She didn't mention the dosage, but i'm assuming its 1 injection ~5ml.

Is this too small a dosage to be effective?

I'm a young healthy man in my early twenties running my own business. It gets mentally draining working long hours and having to make decisions and design strategies on a daily basis. Basically dealing with mentally challenging tasks and stress.

I'm starting piracetam at 1600mg X 2 doses daily too.

Please let me know your thoughts on the recommended cerebrolysin dosage required for healthy individuals and relevant studies if any.

Thanks :laugh:

Cerebrolysin sounds like it's definitely up your alley (high stress, business owner, etc). I'd say 5ml/day (up to 10ml if really mentally stressed) should be good enough. Once a quarter should work, but you could inject more frequently (up to once every.. other month) if you feel the effect wearing off.



The schedule recommended by my friend is 10ml/day 5 days on 2 days off for a total of 100ml. She does this once a year and i don't think she will give me more if I ask for it for fear of my well being.

My question is, are there any long term changes in your brain (negative/positive) or is this a kind of drug that fades as soon as you go off it?

Will I end up dumber or go back to baseline if I go off it for a prolonged period (few years)?

Also since this drug is used predominantly in older folks and people with brain damage, what's the long term effect on young healthy individuals as they approach middle- old age without continuing this drug?

Appreciate any input or researches.

I think it would be good to do it for one month. The effect eventually wears off after about 2-3 months, hence the reason for redoing it. I think there is a graph somewhere that shows the steady decline after stopping, but I can't remember where it is or what it was measuring.

I should add that some regenerative effects are "permanent."




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