2208 replies to this topic

[chairofgold]

I think I am going to try it out because you and some others sound really confident that it nails treatment-resistant depression. I've also found this effect with noopept which acts similarly except way weaker probably. Except I think it fucks up my sleep. Anyway, if cerebrolysin doesn't work I think I'm gonna be done with making purchases for a long ass time lol.

First of all, I would not purchase 400 dollars worth of Cbl, if I were you. I made the mistake a year ago and ended up purchasing Aniracetam, 525 dollars worth, which was something like 2lbs, if I remember correctly and I hardly even use the stuff. It works great, but the taste and reconsumption factor was a big turn off, not considering that it is an actual medication, that may cause damage in the long run. I know for a fact that retail sellers or those that use the medication in hopes, will not want to hear this, so don't be surprised if I get marked with a -1 negative rating. With that being said, I would only buy 2 weeks worth or 10ml x 10, and give it a try.

Cbl, should not cause any damage to your brain such as overusing catecholamines, but rather benefit you for the changes, long-term. Also, every person is conditioned different ( age, gender, height, etc) but yet biologically very similar, so what works well and fast for one person may not work as well and fast for the other person, and vis versa.

Superhumangear would be the lowest price retailer as far as I am aware of. 90 dollars for 10ml x 5 and 16 dollars for shipping, so in total it would cost you 196 dollars. The shipping is the same regardless of the volume, is my understanding.

Second, I can only go by an IV experience, so to speak. I was going to go IM, but changed my mind. The cost for me would be 180 dollars every 8 weeks or like 180 x 6 = $1080 a year minus shipping, so in essence this drug should be considered an investment because of the cost. For some that would cost a lot of money and for others it wouldn't depending on your commitment and finances. I for one, need the medication because of my college studies, and would not be served well without it.

My perception of the drug had changed dramatically in spite of my skepticism, so I know that this for me is the best nootropic out there, hands down in terms of cost vs benefit. In fact Al from superhumangear sent me this email:

Hello,

any update on this order? Sorry for asking but we have a limited stock of this item and the demand is high.

best regards
Al

Third, it takes time and longterm use to work for longterm changes. Be patient.

If you are like me, young, medium build and relatively healthy other than having depression, you should not expect an immediate change for the first week and a half, other than some kind of mild anxiolytic effect, but keep in mind that it is working for you internally. Once the depression goes away, it will of have done it's job.

The making smarter factor is there but you probably wont notice much in the short term, since dendrite extension and branching takes time to grow, like the roots of a plant, if well watered (eating correctly, studying, exercising) , nourished (natural brain supplements such as phosphatidylserine) and fertilize with miracle grow (Cbl) , but are growing in the right condition and environment like receiving higher BDNF, CNTF (again Cbl), etc.

http://www.hypermed....erebrolysin.htm

Last, if you or anyone knows where to get it cheaper, with it being the real mccoy, let us know. We are all into saving money, that is universal.

Edited by chairofgold, 28 August 2012 - 06:04 AM.

[Rior]

I think I am going to try it out because you and some others sound really confident that it nails treatment-resistant depression. I've also found this effect with noopept which acts similarly except way weaker probably. Except I think it fucks up my sleep. Anyway, if cerebrolysin doesn't work I think I'm gonna be done with making purchases for a long ass time lol.

First of all, I would not purchase 400 dollars worth of Cbl, if I were you. I made the mistake a year ago and ended up purchasing Aniracetam, 525 dollars worth, which was something like 2lbs, if I remember correctly and I hardly even use the stuff. It works great, but the taste and reconsumption factor was a big turn off, not considering that it is an actual medication, that may cause damage in the long run. I know for a fact that retail sellers or those that use the medication in hopes, will not want to hear this, so don't be surprised if I get marked with a -1 negative rating. With that being said, I would only buy 2 weeks worth or 10ml x 10, and give it a try.

Cbl, should not cause any damage to your brain such as overusing catecholamines, but rather benefit you for the changes, long-term. Also, every person is conditioned different ( age, gender, height, etc) but yet biologically very similar, so what works well and fast for one person may not work as well and fast for the other person, and vis versa.

Superhumangear would be the lowest price retailer as far as I am aware of. 90 dollars for 10ml x 5 and 16 dollars for shipping, so in total it would cost you 196 dollars. The shipping is the same regardless of the volume, is my understanding.

Second, I can only go by an IV experience, so to speak. I was going to go IM, but changed my mind. The cost for me would be 180 dollars every 8 weeks or like 180 x 6 = $1080 a year minus shipping, so in essence this drug should be considered an investment because of the cost. For some that would cost a lot of money and for others it wouldn't depending on your commitment and finances. I for one, need the medication because of my college studies, and would not be served well without it.

My perception of the drug had changed dramatically in spite of my skepticism, so I know that this for me is the best nootropic out there, hands down in terms of cost vs benefit. In fact Al from superhumangear sent me this email:

Hello,

any update on this order? Sorry for asking but we have a limited stock of this item and the demand is high.

best regards
Al

Third, it takes time and longterm use to work for longterm changes. Be patient.

If you are like me, young, medium build and relatively healthy other than having depression, you should not expect an immediate change for the first week and a half, other than some kind of mild anxiolytic effect, but keep in mind that it is working for you internally. Once the depression goes away, it will of have done it's job.

The making smarter factor is there but you probably wont notice much in the short term, since dendrite extension and branching takes time to grow, like the roots of a plant, if well watered (eating correctly, studying, exercising) , nourished (natural brain supplements such as phosphatidylserine) and fertilize with miracle grow (Cbl) , but are growing in the right condition and environment like receiving higher BDNF, CNTF (again Cbl), etc.

http://www.hypermed....erebrolysin.htm

Last, if you or anyone knows where to get it cheaper, with it being the real mccoy, let us know. We are all into saving money, that is universal.

While I certainly wouldn't recommend anyone spend $400 on a supplement they have yet to try, I also think cerebrolysin is quite different from Aniracetam. I take back what I said earlier, you're right that no other supplements should cause any of the same kind of permanent change as Cerebrolysin. I suppose that's inherent in comparing different mechanisms of action, where regular nootropics only temporarily alter (typically) the AMPA/NMDA system for as long as they're in the body, and cerebrolysin causes actual lasting nerve growth.

That said, I have yet to try cerebrolysin due to lack of funds, though I plan on investing $600 my first time around for the sole sake of taking advantage of the opportunity as much as possible on the first round. 10ml x 30. I've also had about five concussions though, so I've got some real work to do. Pretty excited once I can get enough cash for it. I know I saw a source based in russia that only ships to russia, that I think I remember was selling cerebro for like 10x10ml for $20-30 or something. Pretty unbelievable price. We'd need a re-shipper in russia though, and then the question is whether or not it's the same Ebewe.


Going back to regular nootropics though, although they don't cause permanent change, I still see substantial benefit in their occasional use for regular purposes. For example, I'm in school right now and as I said earlier Pramiracetam is phenomenal for helping me learn. The price isn't too high that it would be a problem either. I am quite a bit surprised you were willing to drop 525 on a supplement you had never tried O.o

[protoject]

I am quite a bit surprised you were willing to drop 525 on a supplement you had never tried O.o

Yeah I know what you guys are saying about not wasting money but cerebrolysin is one of those things where you're instructed to take it for a month while taking weekends off, and if you're gonna do a high dose of 10mL /day you will probably have to shell out a lot of money. I believe some people didn't even feel the benefit until like the 10th day or even longer. So you've got to ask yourself if it's better to waste 400 dollars and have it work or to waste 200 dollars and have it not work. right?

[Rior]

I am quite a bit surprised you were willing to drop 525 on a supplement you had never tried O.o

Yeah I know what you guys are saying about not wasting money but cerebrolysin is one of those things where you're instructed to take it for a month while taking weekends off, and if you're gonna do a high dose of 10mL /day you will probably have to shell out a lot of money. I believe some people didn't even feel the benefit until like the 10th day or even longer. So you've got to ask yourself if it's better to waste 400 dollars and have it work or to waste 200 dollars and have it not work. right?

Yeah I mean, I completely agree with cerebro. That's what I was saying earlier, I think its absolutely worth it to drop a ton on cerebro because its different than anything else. Dammit I've been so excited for so long but just can't afford it right now. Sucks.

[chairofgold]

Guys, I know Cbl is not cheap. I knew that going into it, but because I need the extra helper, I have no choice.

Again, if anyone knows where to get it cheaper than the site listed in previous posts. Let us know!

[protoject]

Guys, I know Cbl is not cheap. I knew that going into it, but because I need the extra helper, I have no choice.

Again, if anyone knows where to get it cheaper than the site listed in previous posts. Let us know!

You can send me some of yours for free, right Chairofgold

[Bentonite]

I'm one of the few who felt nothing from CRB (5ml X 10 IM) last year. Now I think is time for second shot, hoping in a better result. Now my problem are doses and for how much money. I've got a prescription, do you know online places that sell at normalized price with pres? Ideally I was thinking for 10 ml X 20 IV, but only if I can buy at the standard price of Austrian pharmacies....

[protoject]

I'm one of the few who felt nothing from CRB (5ml X 10 IM) last year. Now I think is time for second shot, hoping in a better result. Now my problem are doses and for how much money. I've got a prescription, do you know online places that sell at normalized price with pres? Ideally I was thinking for 10 ml X 20 IV, but only if I can buy at the standard price of Austrian pharmacies....

Do you have any pre-existing condition you are trying to treat or were you simply using it for general cognitive/ energy enhancement?

[Bentonite]

I'm one of the few who felt nothing from CRB (5ml X 10 IM) last year. Now I think is time for second shot, hoping in a better result. Now my problem are doses and for how much money. I've got a prescription, do you know online places that sell at normalized price with pres? Ideally I was thinking for 10 ml X 20 IV, but only if I can buy at the standard price of Austrian pharmacies....

Do you have any pre-existing condition you are trying to treat or were you simply using it for general cognitive/ energy enhancement?

I'm pretty lazy and got problems in concentration. That is.

[protoject]

I'm one of the few who felt nothing from CRB (5ml X 10 IM) last year. Now I think is time for second shot, hoping in a better result. Now my problem are doses and for how much money. I've got a prescription, do you know online places that sell at normalized price with pres? Ideally I was thinking for 10 ml X 20 IV, but only if I can buy at the standard price of Austrian pharmacies....

Do you have any pre-existing condition you are trying to treat or were you simply using it for general cognitive/ energy enhancement?

I'm pretty lazy and got problems in concentration. That is.

Come on! Take one for the team! do it! 10 mL for 4 weeks taking breaks on weekends! you might save me hundreds of dollars in failure.. or maybe.. you will be the new inspiration!

edit: ok maybe I'm being kind of immature, but seriously, I want someone else to get dirty this time, I'm sick of spending my money on false hopes. give me some hope man! lol

Edited by protoject, 01 September 2012 - 03:24 AM.

[Rior]

I'm one of the few who felt nothing from CRB (5ml X 10 IM) last year. Now I think is time for second shot, hoping in a better result. Now my problem are doses and for how much money. I've got a prescription, do you know online places that sell at normalized price with pres? Ideally I was thinking for 10 ml X 20 IV, but only if I can buy at the standard price of Austrian pharmacies....

Do you have any pre-existing condition you are trying to treat or were you simply using it for general cognitive/ energy enhancement?

I'm pretty lazy and got problems in concentration. That is.

Come on! Take one for the team! do it! 10 mL for 4 weeks taking breaks on weekends! you might save me hundreds of dollars in failure.. or maybe.. you will be the new inspiration!

edit: ok maybe I'm being kind of immature, but seriously, I want someone else to get dirty this time, I'm sick of spending my money on false hopes. give me some hope man! lol

Well, that's my intent once I can afford it. 10mL for 4 weeks with breaks on weekends. I'll letcha all know how it goes when I'm done should probably be able to afford it within the next four weeks.

[Bentonite]

I'm one of the few who felt nothing from CRB (5ml X 10 IM) last year. Now I think is time for second shot, hoping in a better result. Now my problem are doses and for how much money. I've got a prescription, do you know online places that sell at normalized price with pres? Ideally I was thinking for 10 ml X 20 IV, but only if I can buy at the standard price of Austrian pharmacies....

Do you have any pre-existing condition you are trying to treat or were you simply using it for general cognitive/ energy enhancement?

I'm pretty lazy and got problems in concentration. That is.

Come on! Take one for the team! do it! 10 mL for 4 weeks taking breaks on weekends! you might save me hundreds of dollars in failure.. or maybe.. you will be the new inspiration!

edit: ok maybe I'm being kind of immature, but seriously, I want someone else to get dirty this time, I'm sick of spending my money on false hopes. give me some hope man! lol

Ahaha. Ehy man, I'm not the most indicated for this request, how I said last year try was a failure. Wrote an email to an Austrain pharmacy on if they can ship the stuff to me if I send them my prescription.

[stablemind]

Has anyone with bipolar disorder tested this compound?

[chairofgold]

I'm one of the few who felt nothing from CRB (5ml X 10 IM) last year. Now I think is time for second shot, hoping in a better result. Now my problem are doses and for how much money. I've got a prescription, do you know online places that sell at normalized price with pres? Ideally I was thinking for 10 ml X 20 IV, but only if I can buy at the standard price of Austrian pharmacies....

Do you have any pre-existing condition you are trying to treat or were you simply using it for general cognitive/ energy enhancement?

Any doctor in their practice would need to come up with an approved medical diagnosis in order to formulate a prescription. The insurance company in turn use the diagnosis for reinversement purposes. Unfortunately in the usa, Cbl is not a FDA approved medication and it cant be prescribed. I'm not sure about Canada though. You ought to check to find out if Cbl is FDA approved there, because if it is you can get a prescription thereby saving $$$.

[Maverick32]

Can someone PM me with a reputable source? Thanks

Edited by Maverick32, 01 September 2012 - 05:12 PM.

[Bentonite]

I'm one of the few who felt nothing from CRB (5ml X 10 IM) last year. Now I think is time for second shot, hoping in a better result. Now my problem are doses and for how much money. I've got a prescription, do you know online places that sell at normalized price with pres? Ideally I was thinking for 10 ml X 20 IV, but only if I can buy at the standard price of Austrian pharmacies....

Do you have any pre-existing condition you are trying to treat or were you simply using it for general cognitive/ energy enhancement?

Any doctor in their practice would need to come up with an approved medical diagnosis in order to formulate a prescription. The insurance company in turn use the diagnosis for reinversement purposes. Unfortunately in the usa, Cbl is not a FDA approved medication and it cant be prescribed. I'm not sure about Canada though. You ought to check to find out if Cbl is FDA approved there, because if it is you can get a prescription thereby saving $$$.

I'm Italian and I've got already a prescription. How do I save money?

[sunnyindia]

Hello friends, please help me

I am 27 year old male from India, I want to clear a country level exam and I am preparing for it , in that exam 10,000,00 people compete at first stage and only 1000 get selected finally after many stages. that exam is not really like going at moon but it requires very good memory, cognitive and reasoning skills. I have only 2 attempts left for it, one attempt a year.

As I read about various brain suppliments I want to take them because :-

1 I lack in concentration, I cant concentrate at one thing at a time, my mind thinks of several other things at one time when I am doing anything lots of thoughts come to my mind when I read or learn, not stable.
**** I already had 300 softgels 2 softgels per day of fishoil OMEGA 3 1200mg per capsule from naturemade and its results are negligible. ****
2. I need to improve memory once only for clearing exam I dont want to be savant for lifetime.
3. I dont have any or ever had any major mental or physical problem like depression or anything,

My questions are :-
0.Is there any suppliment that really work ? its ok if that nootropic will have any curable side effects
1. is cerebrolysin appropriate for my case ?
2. if you would like to suggest any other nootropic for me then I will be very thankful to you all.

Thanks a lot (waiting for your precious replies)

Edited by sunnyindia, 01 September 2012 - 09:22 PM.

[chairofgold]

First off I would like to say that nootropics such as Cerebrolysin will cause stronger brain cells connections, such as in the branching out of dendrites over a period of time. I notice that I am starting to pick things up faster and my verbal reactions to questions are becoming more quicker and more appropriate. I am surprised of that. I am not really known to be witty, but lately I have been!

As far as taking this before an exam, I would have to say that it will not help. The reason being is because I myself am slowly, but slowly becoming more intellectual. This does not happen overnight, nor in weeks, but in months. I speak for myself.

As far as my depression, why it was gone in about 8 days of the medication, but lately, as of last night, I felt depressed. I though, though there had been a depressing situation occur at my work place, though. So I wouldn't say that you will become 100% depressed free, all of the time. What did I do about the situation when I came home? Why I ran on the treadmill, and afterwards my depression alleviated quickly. With that said, you have to help yourself too. Meds aren't 100% cures. Life is full of ups and downs. The good part is that that depression was caused by a certain element, not under my control, and not for no reason at all.

Edited by chairofgold, 02 September 2012 - 06:12 PM.

[protoject]

One thing I really worry about in concern to taking cerebrolysin is not being able to sleep enough. I know noopept has a similar action that is much weaker, and it does help me, but it really fucks up my sleep [and i have problems to begin with so im very sensitive to that effect]. Is this a valid concern?... I also have sleep disrupting effects from melatonin, and maybe not so strangely- as again this raises bdnf/ngf right? Do you think it's got something to do with that?

Edited by protoject, 03 September 2012 - 01:57 PM.

[Bentonite]

Noopept with Cerebrolysin anyone?

[protoject]

First off I would like to say that nootropics such as Cerebrolysin will cause stronger brain cells connections, such as in the branching out of dendrites over a period of time. I notice that I am starting to pick things up faster and my verbal reactions to questions are becoming more quicker and more appropriate. I am surprised of that. I am not really known to be witty, but lately I have been!

As far as taking this before an exam, I would have to say that it will not help. The reason being is because I myself am slowly, but slowly becoming more intellectual. This does not happen overnight, nor in weeks, but in months. I speak for myself.

I know what you mean here, I noticed the same with noopept. It works better and better as I keep taking it. However the sleep disruption also accumulated and made everything worse. So I hope that in the future when i try cerebrolysin it will not disrupt my sleep in the same way as noopept and melatonin do. I really hope my sleep issue has nothing to do with BDNF or NGF though I really think it does based on my response to these other medications. Sadly I also think my depression problems are stemming from the same area...

[chairofgold]

First off I would like to say that nootropics such as Cerebrolysin will cause stronger brain cells connections, such as in the branching out of dendrites over a period of time. I notice that I am starting to pick things up faster and my verbal reactions to questions are becoming more quicker and more appropriate. I am surprised of that. I am not really known to be witty, but lately I have been!

As far as taking this before an exam, I would have to say that it will not help. The reason being is because I myself am slowly, but slowly becoming more intellectual. This does not happen overnight, nor in weeks, but in months. I speak for myself.

I know what you mean here, I noticed the same with noopept. It works better and better as I keep taking it. However the sleep disruption also accumulated and made everything worse. So I hope that in the future when i try cerebrolysin it will not disrupt my sleep in the same way as noopept and melatonin do. I really hope my sleep issue has nothing to do with BDNF or NGF though I really think it does based on my response to these other medications. Sadly I also think my depression problems are stemming from the same area...

Cbl will disturb sleep if you consume stimulants such as caffeine in conjunction. I actually drink coffee and take Cbl, because the two work synergistic together in giving me brain energy that I need. Albeit, when you are a full time student and need to study 8 plus hrs a day, studying will almost alway make you sleepy and tired. The mental energy expounded during the course of a day makes me sleepy at the end of the day, so hand in hand it works well for me that way. I will warn you that if you do combine coffee with Cbl it will increase your heart rate and blood pressure. Lucky for me, I have a prescription for Lisinopril which is a BP med that I take daily.



i

Edited by chairofgold, 03 September 2012 - 09:50 PM.

[Bentonite]

So what about Noopept and CBL together?

[chairofgold]

So what about Noopept and CBL together?

What is noopept? I've never use it.

[motomatt]

So what about Noopept and CBL together?

What is noopept? I've never use it.

http://en.wikipedia.org/wiki/Noopept




From Wikipedia, the free encyclopedia
Jump to: navigation, search
Noopept Systematic (IUPAC) name N-phenylacetyl-L-prolylglycine ethyl ester Clinical data Pregnancy cat. ? Legal status legal Identifiers CAS number 157115-85-0 ATC code ? PubChem CID 180496 Chemical data Formula C₁₇H₂₂N₂O₄ Mol. mass 318.367 g/mol

SMILES(what is this?) (verify)
Noopept (Russian: Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic remedy. It is derived from the racetam family of drugs and shares similar mechanisms of action,^[1][2] but is, according to studies, 1000 times more potent than the prototypical racetam drug, piracetam.^[3] Animal studies have shown noopept to be neuroprotective and enhance memory in various tests.^{[4][5][6][7][8]} Unusually for a peptide-derived compound, noopept displays both high oral bioavailability^[9] and good blood–brain barrier penetration^[10] in rats (although a previous study concluded that "GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection" and that administration of Noopept only increases the concentration of endogenous nootropic Cyclo-L-prolylglycine^[2]), and human studies have shown promising results, with potential application in the treatment of Alzheimer's disease.^[11] It is also an "immunocorrector" in mice.^[12]
It has been found to stimulate the expression of NGF and BDNF in rat hippocampus. Expression of the studied neurotropic factors in the cerebral cortex was below the control after single administration of Noopept, while chronic administration caused a slight increase in BDNF expression. In the hippocampus, expression of mRNA for both neurotrophins increased after acute administration of Noopept. Chronic treatment with Noopept was not followed by the development of tolerance, but even potentiated the neurotrophic effect.^[7]

[chairofgold]

So what about Noopept and CBL together?

What is noopept? I've never use it.

http://en.wikipedia.org/wiki/Noopept




From Wikipedia, the free encyclopedia
Jump to: navigation, search
Noopept Systematic (IUPAC) name N-phenylacetyl-L-prolylglycine ethyl ester Clinical data Pregnancy cat. ? Legal status legal Identifiers CAS number 157115-85-0 ATC code ? PubChem CID 180496 Chemical data Formula C₁₇H₂₂N₂O₄ Mol. mass 318.367 g/mol

SMILES(what is this?) (verify)
Noopept (Russian: Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic remedy. It is derived from the racetam family of drugs and shares similar mechanisms of action,^[1][2] but is, according to studies, 1000 times more potent than the prototypical racetam drug, piracetam.^[3] Animal studies have shown noopept to be neuroprotective and enhance memory in various tests.^{[4][5][6][7][8]} Unusually for a peptide-derived compound, noopept displays both high oral bioavailability^[9] and good blood–brain barrier penetration^[10] in rats (although a previous study concluded that "GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection" and that administration of Noopept only increases the concentration of endogenous nootropic Cyclo-L-prolylglycine^[2]), and human studies have shown promising results, with potential application in the treatment of Alzheimer's disease.^[11] It is also an "immunocorrector" in mice.^[12]
It has been found to stimulate the expression of NGF and BDNF in rat hippocampus. Expression of the studied neurotropic factors in the cerebral cortex was below the control after single administration of Noopept, while chronic administration caused a slight increase in BDNF expression. In the hippocampus, expression of mRNA for both neurotrophins increased after acute administration of Noopept. Chronic treatment with Noopept was not followed by the development of tolerance, but even potentiated the neurotrophic effect.^[7]

It could be a winning combination in conjunction with Cbl, then maybe not. The problem with the racetams is it's overuse on glutamine and the receptors of glutamine. I in particular am not fond of nootropics of that nature, but who am I to say. I'll leave that up to the noopept users.

Long-term dendrite braching is at question here.

[Maverick32]

Has anyone had a problem with IAS' stuff?

[stablemind]

So what about Noopept and CBL together?

What is noopept? I've never use it.

http://en.wikipedia.org/wiki/Noopept




From Wikipedia, the free encyclopedia
Jump to: navigation, search
Noopept Systematic (IUPAC) name N-phenylacetyl-L-prolylglycine ethyl ester Clinical data Pregnancy cat. ? Legal status legal Identifiers CAS number 157115-85-0 ATC code ? PubChem CID 180496 Chemical data Formula C₁₇H₂₂N₂O₄ Mol. mass 318.367 g/mol

SMILES(what is this?) (verify)
Noopept (Russian: Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic remedy. It is derived from the racetam family of drugs and shares similar mechanisms of action,^[1][2] but is, according to studies, 1000 times more potent than the prototypical racetam drug, piracetam.^[3] Animal studies have shown noopept to be neuroprotective and enhance memory in various tests.^{[4][5][6][7][8]} Unusually for a peptide-derived compound, noopept displays both high oral bioavailability^[9] and good blood–brain barrier penetration^[10] in rats (although a previous study concluded that "GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection" and that administration of Noopept only increases the concentration of endogenous nootropic Cyclo-L-prolylglycine^[2]), and human studies have shown promising results, with potential application in the treatment of Alzheimer's disease.^[11] It is also an "immunocorrector" in mice.^[12]
It has been found to stimulate the expression of NGF and BDNF in rat hippocampus. Expression of the studied neurotropic factors in the cerebral cortex was below the control after single administration of Noopept, while chronic administration caused a slight increase in BDNF expression. In the hippocampus, expression of mRNA for both neurotrophins increased after acute administration of Noopept. Chronic treatment with Noopept was not followed by the development of tolerance, but even potentiated the neurotrophic effect.^[7]

It could be a winning combination in conjunction with Cbl, then maybe not. The problem with the racetams is it's overuse on glutamine and the receptors of glutamine. I in particular am not fond of nootropics of that nature, but who am I to say. I'll leave that up to the noopept users.

Long-term dendrite braching is at question here.

Are there other drugs like this? Or is this the only one of its kind?

[chairofgold]

Has anyone taken Cerebrolysin for years, like one year and over on a consistent basis?

Do you feel your memory, mood, and cognitive thinking has improved significantly?

I'll tell my recent experiences after 4 weeks of treatment soon!

[protoject]

Hey I am wondering if anyone would recommend 10 mL over 5 mL / d. I'm asking because originally, I figured I should take 5mL, but then after some consideration thought if 10mL gives a stronger effect and quicker, then I would rather use that. I was also paranoid that perhaps 5mL wouldn't give me any effect whereas 10mL would more surely give me an effect so that I couldn't doubt it if it were there. However on second though I've been thinking maybe I should play it moderate, not jump into things too quickly, just try the regular 5mL for a month instead, save some money, and maybe get a good effect without needing more, what do you peeps think?