This topic is locked
^ Storing a sterile syringe in a plastic bag in the fridge is what I've done as well. I've taken 10mL ampules and divided it into two 5mL doses, one per each day, in order to save on costs (considering 10mL ampules cost less money than 5mL per actual mL).
My updated opinion of Cerebrolysin is as follows:
5x5mL Cere dosing in the morning, taking weekends off is ideal for me.
Initial pre-loading dose of 10mL, 5mL in the morning and 5mL at night, for two days, seemed optimal for me to jumpstart the process. When I first started using Cerebrolysin, it was immediately followed by a dramatic clarity of thought, quickening of speech and dramatically increased cleverness that could not possibly be associated with placebo. (After having used cere times in the past and used many other supplements, I can more or less completely rule out placebo when it's happening) It was very, very noticeable. My thoughts felt much more malleable.
HOWEVER.
After about three days of consecutive dosing, the immediate effects fell by the wayside a little bit and led to what I consider to be a multimodal effect of the drug. I remember saying this last time I used cere too, about a year and a half ago. Acute Cere effects (after 3 days of consecutive dosing) include a great anxiolytic effect, accompanied by mild brain fog. The initial acute mental stimulation I received did not last past the 3 day mark, and was instead replaced with mild acute brain fog accompanied by said anxiolytic effect. That said, however, it is multimodal in that after the 3 day mark the acute effect seems very different than the effect 12 hours after dosing. 12 hours after dosing the acute brain fog is lifted, and instead replaced by a very refreshed, clear state of mind quite like the initial brain boosting effects I experienced the first 3 days. Not as strong as the initial effects, but nice and enjoyable nonetheless. This is one of the reasons I suggest two days off for every 5 days on.
My reasoning for this multimodal effect:
The initial boosting response I received was largely due to the flood of amino acids into my brain. That flood of amino acids by itself won't cause dramatic neurogenesis, but it certainly will boost the effect of neurons already present. Neurogenesis isn't very apparent for the first couple days, and that loading phase is the process by which my brain is acclimating to the Cerebrolysin and preparing for neurogenesis to a larger extent. After 3 days, however, is when the neurogenesis really begins. Any neurogenic compounds I've used so far (Lion's mane, Cerebrolysin, NSI-189, others that I can't remember) have all given mild brain fog as a result of what should be increased neurotrophic factors and increased neurogenesis. There are many others who report brain fog as a result of neurogenesis/neurogenic compounds as well. As such, when the actual neurogenesis begins to take full force after 3 days, brain fog becomes apparent during its acute mode of action, and this is later followed by the delayed response of clarity caused partially by the remaining amino acids, as well as relaxation from the exhausting effects of neurogenesis.
Increased neurogenesis increases use of available resources, which is why I might guess it causes brain fog. After the mostly neurogenic/neurotrophic compounds have been used (I believe I remember reading that Cerebrolysin maintains action in your body up to 18 hours. I can't remember the source for this, I'll link it if I find it) then your brain relaxes from building neurons and you are no longer using a higher amount of resources. This is what leads to the clarity, as neurons are built for use and you still probably have some amino acids maintained, but you're no longer in that *extreme* building phase.
I liken it to physical exercise and working out. When you're building your body, it takes a tremendous amount of energy when you're actually working out. You might feel exhausted after you're done exercising. But some time later, after you're no longer using extreme energy expenditure, you feel fantastic in comparison and you've built strength. I hope that makes sense in regards to Cerebrolysin.
Anyway, this is all ultimately conjecture. It's conjecture based on the neuroscience I know and have learned through my University, but it is conjecture nonetheless. If anyone agrees or disagrees with me, obviously feel free to say so as I think it's an important topic for discussion.
